Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: March 3, 2025

Objectives This study aims to systematically evaluate the efficacy of acupuncture on stroke-associated pneumonia (SAP). Methods English and Chinese databases were searched from their inception until 15 March 2024 collect randomized controlled trials (RCTs). The risk bias was assessed using Cochrane collaboration tools. RevMan 5.4.0 software used analyze included studies, Grades Recommendations, Assessment, Development, Evaluation (GRADE) assessment quality outcomes. Results 16 studies involving 1,125 patients in this meta-analysis. Compared with control group, results showed that significantly improved effective rate [RR = 1.20, 95% CI (1.13, 1.27), P < 0.00001] reduced level white blood cells (WBC) [MD −6.52, (−8.31, −4.73), 0.00001], C reactive protein (CRP) −6.50, (−9.97, −3.03), 0.0002], neutrophil percentage (Neu%) −6.66, (−8.96, −4.36), procalcitonin (PCT) −0.81, (−1.21, −0.40), 0.0001]. Additionally, therapy shortened duration coughing −3.22, (−4.73, −1.72), 0.0001], disappearance rales −3.99, (−6.44, −1.54), 0.001], antibiotic use −4.51, (−5.46, −3.57), 0.00001]. It also clinical pulmonary infection score (CPIS) −1.71, (−2.71, −0.71), 0.0008] National Institute Health Stroke Scale (NIHSS) −3.93, (−5.78, −2.09), Moreover, increased forced vital capacity (FVC) 0.46, (0.02, 0.89), 0.04] Forced Expiratory Volume One Second (FEV 1 ) 0.49, (0.14, 0.84), 0.006]. Conclusion found has a positive effect treating SAP. However, owing low-quality evidence, more rigorous are needed coming years confirm these findings. Systematic review registration https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462846, identifier CRD42023462846.

Language: Английский

Association between nutritional status and pneumonia in patients with spontaneous intracerebral hemorrhage

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 12, 2025

Background Stroke-associated pneumonia (SAP) is a common and serious complication in patients with spontaneous intracerebral hemorrhage (SICH), contributing to prolonged hospital stays poor outcomes. Nutritional status has been linked the development of SAP ischemic stroke, but its role SICH remains understudied. This study aims evaluate predictive value Risk Screening-2002 (NRS-2002) score for compare it other nutritional assessment tools. Methods retrospective observational included 404 consecutive admitted Dongyang People’s Hospital from January 2023 May 2024. risk was assessed using NRS-2002 upon admission, diagnosed within first 7 days hospitalization. Univariate multivariate logistic regression analyses identified factors SAP, receiver operating characteristic (ROC) curves were used accuracy NRS-2002, Controlling Status (CONUT) score, Prognostic Index (PNI) SAP. Results Among patients, 97 developed A higher significantly associated an increased (OR: 1.575, 95% CI: 1.134–2.186, p = 0.007). ROC analysis showed that (AUC: 0.768, 0.716–0.820) outperformed CONUT 0.597, 0.530–0.663) PNI 0.588, 0.519–0.657) predicting ( < 0.05). Subgroup revealed ≥ 3 particularly weight loss, severe those without hypertension or diabetes. Conclusion The valuable predictor scores correlating highlights importance early identifying high-risk potentially guiding clinical interventions reduce incidence.

Language: Английский