<strong>Dystonia, Tremor, and Dystonic Tremor</strong>

Published: March 22, 2024

Dystonia and tremor are distinct movement disorders, but they overlap in certain circumstances. First, dystonia may co-exist the same individual, or different regions of body. Second, dystonic movements sometimes rapid repetitive, mimic tremor. The term first appeared literature to describe a repetitive that mimicked could be discriminated from essential With consensus statement on tremor, was instead used any combination with body region, definition retained latest statement. Both definitions continue modern literature. To address this problem, group specialists met review problem develop recommendations for more consistent approach. agreed terminology applied clinic essential, even though laboratory-based measures required. also should exclusively refer rhythmic movements, establishment boundaries rhythmicity is needed. grossly arrhythmic context dystonia, called jerky rather than terms imply Moreover, when both coexist, described according affected given labels.

Language: Английский

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The Application of Transcranial Electrical Stimulation in Sports Psychology

Computational and Mathematical Methods in Medicine, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 11

Published: July 13, 2022

The problem of sports psychological fatigue has become one the focal points common concern among scholars at home and abroad. Athletes will face many problems challenges in competition or training, if they are not handled properly, have negative experiences, which affect training benefits develop fatigue. Transcranial electrical stimulation (TES), contains transcranial direct current stimulation, alternating random noise is a noninvasive brain method. By applying specific patterns low-intensity currents to regions through electrodes different sizes, it modulates cortical neural activity and/or excitability enhances connections between nerves muscles achieve improved motor performance. TES technology currently making transition from laboratory research applied science. In this paper, we first describe mechanisms action on cerebral cortex, including five aspects body balance, endurance performance, exercise fatigue, muscle strength, learning ability; then, review relevant studies application functional connectivity networks explore importance field for improve athletic This provides machine learning-based model locomotor rock climbers since climbing sport that places great demands athletes' quality. factors influencing intervention measures beneficial early diagnosis prevention it.

Language: Английский

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Tremor Phenomenology and Pathophysiology

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

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Response of neuronal populations to phase-locked stimulation: model-based predictions and validation

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

Abstract Background Modulation of neuronal oscillations holds promise for the treatment neurological disorders. Nonetheless, stimulating populations in a continuous open-loop manner can lead to side effects and suboptimal efficiency. Closed-loop strategies such as phase-locked stimulation aim address these shortcomings by offering more targeted modulation. While theories have been developed understand neural response stimulation, their predictions not thoroughly tested using experimental data. Objective We aimed test mathematical model regarding stimulation. Methods Using coupled oscillator model, we expanded on two key describing function phase amplitude ongoing activity. To investigate predictions, analyzed electrocorticogram (ECoG) recordings from previously conducted study Parkinsonian rats, extracted corresponding curves. Results demonstrated that is strongly correlated derivative ( ρ > 0.8) all animals except one, thereby validating prediction. The second prediction postulated becomes ineffective when network synchrony high, trend appeared missing Our analysis explained this discrepancy showing rats did reach level which theory would predict Conclusions results highlight potential fine-tuning paradigms informed models consider both oscillation.

Language: Английский

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Towards phenotype-specific, non-invasive therapeutic interventions for tremor

Clinical Neurophysiology, Journal Year: 2022, Volume and Issue: 140, P. 169 - 170

Published: May 11, 2022

Language: Английский

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Phase-specific Deep Brain Stimulation revisited: effects of stimulation on postural and kinetic tremor

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: June 21, 2022

Abstract Background In Essential tremor (ET), involuntary shaking of the upper limbs during isometric muscle contraction closely reflects patterns neural activity measured in thalamus - a key element tremorgenic circuit. Phase-specific deep brain stimulation (DBS) builds upon this observation while using accelerometery trembling limb to trigger repetitive electrical perturbations and surrounding areas at specific time within cycle. This closed-loop strategy has been shown induce clinically significant postural relief delivering less than half energy conventional DBS. Objective The main aim study was evaluate treatment efficacy across different contexts movement states. Methods We used digitizing tablet record peripheral dynamics 4 DBS implanted ET patients alternating strategies (no stimulation, continuous open-loop phase-specific) states (intermittent posture holding spiral drawing). Results addition observing suppressive effect phase-specific on both kinetic tremor, our results reinforce role phase-specificity achieve control motor highlight difficulty quantifying phase-dependent effects movement. Moreover, supports hypothesis that with more stable characteristics benefit most from Conclusions By creating better understanding dynamic relationship between central activity, provides important insights for development effective patient context-specific therapeutic approaches ET.

Language: Английский

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