Adult Vaccine Coadministration Is Safe, Effective, and Acceptable: Results of a Survey of the Literature

Influenza and Other Respiratory Viruses, Journal Year: 2025, Volume and Issue: 19(3)

Published: March 1, 2025

Coadministration of vaccines in children is a long-standing practice that has proven to be safe and effective improving the efficiency vaccine administration, thereby increasing immunization coverage rates. As number routinely recommended for adults increases, with limited opportunities have preventive health touchpoints providers, adult coadministration should considered as routine improve vaccination rates public health. A review existing literature was conducted examine potential reactogenicity impact on effectiveness when co-administering adults. Medline searched research articles search term "influenza vaccine" or "vaccination," combined terms "simultaneous," "concomitant," "concurrent," "combination." Another "vaccination" following individual terms: "RSV," "COVID," "Tdap." The references extracted were also examined other relevant articles. Adult all combinations we assessed. Most adverse events (AEs) generally mild moderate short duration. Some studies showed slightly more but few no serious AEs safety signals. Nearly every study confirmed had significant effect immune response either vaccine. benefits outweigh risks. It increases convenience vaccinees, reduces missed vaccinate, contributes efficient use healthcare resources.

Language: Английский

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Co-Administration of BNT162b2 COVID-19 and Influenza Vaccines in Adults: A Global Systematic Review

Vaccines, Journal Year: 2025, Volume and Issue: 13(4), P. 381 - 381

Published: April 2, 2025

Background/Objectives: Co-administration of BNT162b2 with licensed seasonal influenza vaccines (SIVs) is recommended by health authorities. We provide a comprehensive summary the data supporting this practice in adults. Methods: This systematic review consolidates available evidence on prevalence, safety, immunogenicity, efficacy, and effectiveness co-administering SIVs. Searches were conducted for English studies adults ≥ 18 years age between January 2021 August 2024, no geographic restriction. Study quality was assessed using Cochrane RoB 2.0 Newcastle–Ottawa Scale. Results: Twenty (15 observational 5 clinical trials) included, mainly seven countries Europe North America. Eight reported twelve safety/reactogenicity, six three evaluated efficacy/effectiveness. Reported co-administration SIVs increased over time. Of persons receiving BNT162b2, proportion that co-administered from 2.7% to 34.1% 2023. Although variability outcomes observed, consistent pattern indicating negative impact immunogenicity same-day identified. Effectiveness not observed change when BNT162B2 The incidence systemic local adverse events comparable individuals separately those them co-administered. Conclusions: findings indicate both safe effective. highlights value co-administration, which could enhance vaccine uptake streamlining immunization protocols reducing visits.

Language: Английский

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COVID-19 Vaccination Strategies in the Endemic Period: Lessons from Influenza

Vaccines, Journal Year: 2024, Volume and Issue: 12(5), P. 514 - 514

Published: May 9, 2024

Coronavirus disease 2019 (COVID-19) is a highly contagious zoonotic respiratory with many similarities to influenza. Effective vaccines are available for both; however, rapid viral evolution and waning immunity make them virtually impossible eradicate vaccines. Thus, the practical goal of vaccination reduce incidence serious illnesses death. Three years after introduction COVID-19 vaccines, optimal strategy in endemic period remains elusive, health authorities worldwide have begun adopt various approaches. Herein, we propose based on data until early 2024 discuss aspects that require further clarification better decision making. Drawing from comparisons between influenza strategies, our proposed prioritizes high-risk groups, emphasizes seasonal administration aligned campaigns, advocates co-administration increase coverage.

Language: Английский

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Simultaneous vaccination against seasonal influenza and COVID-19 among the target population in Italy

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Aug. 6, 2024

Annual influenza and COVID-19 vaccinations are effective tools for reducing the disease burden. The goals of present cross-sectional survey were to investigate attitudes behaviors toward simultaneous vaccination against seasonal factors associated.

Language: Английский

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