Early-life stress sensitizes response to future stress: Evidence and mechanisms DOI Creative Commons
Catherine J. Peña

Neurobiology of Stress, Journal Year: 2025, Volume and Issue: 35, P. 100716 - 100716

Published: March 1, 2025

Early-life stress sensitizes individuals to additional stressors and increases lifetime risk for mood anxiety disorders. Research in both human populations rodent models of early-life have sought determine how different types contribute vulnerability, whether there are developmental sensitive periods such effects. Although differences the type timing paradigms led specific behavioral outcomes, this complexity is present among humans as well. Robust research now shows sensitivity future at behavioral, neural circuit, molecular levels. These recent discoveries laying foundation translation more effective interventions relevant those who experienced childhood trauma.

Language: Английский

Early-life stress sensitizes response to future stress: Evidence and mechanisms DOI Creative Commons
Catherine J. Peña

Neurobiology of Stress, Journal Year: 2025, Volume and Issue: 35, P. 100716 - 100716

Published: March 1, 2025

Early-life stress sensitizes individuals to additional stressors and increases lifetime risk for mood anxiety disorders. Research in both human populations rodent models of early-life have sought determine how different types contribute vulnerability, whether there are developmental sensitive periods such effects. Although differences the type timing paradigms led specific behavioral outcomes, this complexity is present among humans as well. Robust research now shows sensitivity future at behavioral, neural circuit, molecular levels. These recent discoveries laying foundation translation more effective interventions relevant those who experienced childhood trauma.

Language: Английский

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