ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(43), P. 58072 - 58099
Published: Oct. 21, 2024
Atherosclerosis-induced
coronary
artery
disease
is
a
major
cause
of
cardiovascular
mortality.
Clinically,
conservative
treatment
strategies
for
atherosclerosis
still
focus
on
lifestyle
interventions
and
the
use
lipid-lowering
anticoagulant
medications.
Despite
achieving
some
therapeutic
effects,
these
approaches
are
limited
by
low
bioavailability,
long
intervention
periods,
significant
side
effects.
With
advancement
nanotechnology,
nanomaterials
have
demonstrated
extraordinary
potential
in
biomedical
field.
Their
excellent
biocompatibility,
surface
modifiability,
high
targeting
capability
not
only
enable
efficient
diagnosis
plaque
progression
but
also
allow
precise
drug
delivery
within
atherosclerotic
plaques,
significantly
enhancing
bioavailability
reducing
systemic
Here,
we
systematically
review
current
research
progress
field
to
summarize
types
their
applications
both
atherosclerosis.
Notably,
context
therapy,
provide
comprehensive
overview
nanomaterial
based
targeted
systems
different
cell
plaques.
Additionally,
address
persistent
challenge
clinical
translation
summarizing
issues
providing
directions
innovation
improvement
design.
Overall,
believe
that
this
summarizes
challenges
thereby
offering
insights
references
development
materials
Materials Today Electronics,
Journal Year:
2023,
Volume and Issue:
5, P. 100055 - 100055
Published: Aug. 11, 2023
As
personal
portable
devices,
wearable
sensors
supply
a
leading-edge
pathway
to
diagnose
various
diseases
through
actuating
biological,
physical,
and
chemical
sensing
capabilities.
This
could
be
commonly
carried
out
via
recording
continuous
real-time
of
the
patient's
physiological
statuses,
as
well
pathophysiological
information.
Although
sensor
technology
is
in
infancy
stage,
tremendous
attempts
have
been
devoted
approaching
flexible
polymeric
sensors.
Among
polymer
candidates
applicable
for
synthesizing
sensors,
bio-based
ones
piqued
more
interest
due
their
biocompatibility,
biodegradability,
eco-friendly
features,
cost-effectiveness.
Additionally,
several
fabrication
techniques
professed
architect
efficient
frameworks,
such
films,
hydrogels,
aerogels,
ferrogels,
3D
layers,
electrospun
mats,
textiles.
In
this
review,
different
mechanisms
declared
engineer
are
overviewed.
Then,
regarding
advantages
observed
polymers,
focused
studies
on
natural-based
described.
Notably,
cellulose,
chitosan,
silk,
gelatin,
alginate's
role
functionality
highlighted.
Accordingly,
review
has
opened
new
window
ahead
opportunities
based
natural
polymers.
It
hoped
that
generation
will
launched
by
combining
emerging
achievements
obtained
from
employing
sustainable
green
elements
miniaturized
structures.
Biomass Conversion and Biorefinery,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Sept. 15, 2023
Abstract
Many
research
papers
are
currently
being
written
about
various
methodologies
for
the
green
synthesis
of
ZnO
nanoparticles.
In
this
study,
nanoparticles
were
prepared
by
method
using
baker’s
yeast
(
Saccharomyces
cerevisiae
).
The
characterization
produced
involved
utilization
XRD,
FTIR,
SEM,
and
TEM.
investigation
assessment
antimicrobial
potential
photocatalytic
degradation
efficacy
synthesized
materials
through
Eriochrome
Black
T
(EBT).
results
indicate
that
exhibit
a
spherical
morphology,
exhibiting
diameters
ranging
from
13.0
to
20.0nm,
with
an
average
particle
size
15.0nm.
against
S.
aureus
)
gram-positive
E.
coli
gram-negative
bacteria
was
tested
conduction
zone
inhibition
(ZOI)
minimum
inhibitory
concentration
(MIC)
tests.
This
focused
on
study
photocatalytic-degradation
EBT
in
presence
ultraviolet
light.
experiments
impact
factors,
such
as
pH
levels,
initial
concentration,
nanocatalyst
dosage,
observed
efficiency.
vitro
ZOI
MIC
assay,
it
(NPs)
exhibited
greater
,
measuring
23.1
mm
0.625
μg/ml.
contrast,
effectiveness
ZnO-NPs
comparatively
lower,
indicated
17.0
1.250μg/ml.
greatest
elimination,
which
achieved
83.0%
equilibrium,
found
employing
20.0mg
NPs
at
3.0,
according
activity
results.
synthetic
powerful
antibacterial
agents
effective
may
be
used
treatment
wastewater.
Foods,
Journal Year:
2023,
Volume and Issue:
12(14), P. 2709 - 2709
Published: July 15, 2023
While
recognizing
the
gaps
in
pesticide
regulations
that
impact
consumer
safety,
public
health
concerns
associated
with
contamination
of
foods
are
pointed
out.
The
strategies
and
research
directions
proposed
to
prevent
and/or
reduce
adverse
effects
on
human
environment
discussed.
Special
attention
is
paid
organophosphate
pesticides,
as
widely
applied
insecticides
agriculture,
veterinary
practices,
urban
areas.
Biotic
abiotic
for
degradation
discussed
from
a
food
safety
perspective,
indicating
challenges
potential
further
improvements.
As
systems
endangered
globally
by
unprecedented
challenges,
there
an
urgent
need
harmonize
improve
methodologies
area
protect
health.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(9), P. 4469 - 4494
Published: Sept. 9, 2024
Lung
cancer
remains
a
global
health
concern,
demanding
the
development
of
noninvasive,
prompt,
selective,
and
point-of-care
diagnostic
tools.
Correspondingly,
breath
analysis
using
nanobiosensors
has
emerged
as
promising
noninvasive
nose-on-chip
technique
for
early
detection
lung
through
monitoring
diversified
biomarkers
such
volatile
organic
compounds/gases
in
exhaled
breath.
This
comprehensive
review
summarizes
state-of-the-art
breath-based
diagnosis
employing
chemiresistive-module
supported
by
theoretical
findings.
It
unveils
fundamental
mechanisms
biological
basis
biomarker
generation
associated
with
cancer,
technological
advancements,
clinical
implementation
nanobiosensor-based
analysis.
explores
merits,
challenges,
potential
alternate
solutions
implementing
these
settings,
including
standardization,
biocompatibility/toxicity
analysis,
green
sustainable
technologies,
life-cycle
assessment,
scheming
regulatory
modalities.
highlights
nanobiosensors'
role
facilitating
precise,
real-time,
on-site
leading
to
improved
patient
outcomes,
enhanced
management,
remote
personalized
monitoring.
Additionally,
integrating
biosensors
artificial
intelligence,
machine
learning,
Internet-of-things,
bioinformatics,
omics
technologies
is
discussed,
providing
insights
into
prospects
intelligent
sniffing
nanobiosensors.
Overall,
this
consolidates
knowledge
on
breathomic
biosensor-based
screening,
shedding
light
its
significance
applications
advancing
medical
diagnostics
reduce
burden
hospitals
save
human
lives.
ECS Journal of Solid State Science and Technology,
Journal Year:
2024,
Volume and Issue:
13(4), P. 047004 - 047004
Published: April 1, 2024
Early
diagnosis
through
noninvasive
tools
is
a
cornerstone
in
the
realm
of
personalized
and
medical
healthcare,
averting
direct/indirect
infection
transmission
directly
influencing
treatment
outcomes
patient
survival
rates.
In
this
context,
optical
biochip
breathomic
sensors
integrated
with
nanomaterials,
microfluidics,
artificial
intelligence
exhibit
potential
to
design
next-generation
intelligent
diagnostics.
This
cutting-edge
tool
offers
variety
advantages,
including
being
economical,
compact,
smart,
point
care,
highly
sensitive,
noninvasive.
makes
it
an
ideal
avenue
for
screening,
diagnosing,
prognosing
various
high-risk
diseases/disorders
by
detecting
associated
breath
biomarkers.
The
underlying
detection
mechanism
relies
on
interaction
biomarkers
sensors,
which
causes
modulations
fundamental
attributes,
such
as
surface
plasmon
resonance,
fluorescence,
reflectance,
absorption,
emission,
phosphorescence,
refractive
index.
Despite
these
remarkable
commercial
development
faces
challenges,
insufficient
support
from
clinical
trials,
concerns
about
cross-sensitivity,
challenges
related
production
scalability,
validation
issues,
regulatory
compliance,
contrasts
conventional
perspective
article
sheds
light
state
disease
diagnosis,
addresses
proposes
alternative
solutions,
explores
future
avenues
revolutionize
healthcare
Current Opinion in Environmental Science & Health,
Journal Year:
2024,
Volume and Issue:
unknown, P. 100532 - 100532
Published: Jan. 1, 2024
Proper
vigilance
on
the
levels
of
various
gases
concern,
especially
toxic
ones,
is
vital
for
reducing
risk
environmental
damage.
This
impels
demand
highly
accurate
and
adequate
gas
sensing
systems
which
are
in
but
not
practice.
gap
can
be
filled
by
5th-generation
nano-enabled
sensors
offer
room-temperature
sensing,
flexibility,
high
selectivity,
low
cost,
self-powered
operation,
humidity
resistance,
portable
size.
These
features
key
requirements
integrating
into
modern
Internet-of-things
(IoT)
systems.
perspective
highlights
trends
progressions
(2020-2023)
developing
tailored
nanomaterials
to
fabricate
cutting-edge
performance
desired
manner
conditions,
example,
point-of-care
(POC),
point-of-location
testing.
The
challenges
associated
with
such
materials
scientific
endeavors
address
issues
have
also
been
discussed.
