A biocompatible drug controlled release system based on β-cyclodextrin crosslinked magnetic lactose/ZIF-8 metal-organic frameworks for cancer treatment

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: 703, P. 135227 - 135227

Published: Aug. 30, 2024

Language: Английский

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Enhancement of stability and activity of zinc carbonate nanoparticles using chitosan, hydroxyethyl cellulose, methyl cellulose and hyaluronic acid for multifaceted applications in medicine

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139768 - 139768

Published: Jan. 1, 2025

Language: Английский

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Functionalized ZIF-8 as a versatile platform for drug delivery and cancer therapy: strategies, challenges and prospects

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review discusses the functionalization strategies of ZIF-8 and challenges future developments in ZIF-8-based platforms for drug delivery cancer therapy.

Language: Английский

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Enhanced Cancer Therapy Using Modified Magnetic α-FeO/FeO Nanorods: Dual Role in Curcumin Delivery and Ferroptosis Induction

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114689 - 114689

Published: April 1, 2025

Language: Английский

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Highly efficient MnOX/TiO2@NH2-ZIF-8 composite for the removal of toxic textile dyes from water

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136882 - 136882

Published: April 1, 2025

Language: Английский

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Hyaluronic Acid‐Mediated Ge_0.5Fe_2.5O₄ Nanoparticles: In Relation to Photocatalytic Performance for Organic Dye Degradation

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(16)

Published: April 1, 2025

Abstract The present study reports the systematic synthesis, characterization, and photocatalytic evaluation of germanium‐substituted iron oxide (Ge 0.5 Fe 2.5 O 4 ) nanoparticles with varying concentrations hyaluronic acid (HA). synthesized were characterized using X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) analysis. XRD confirmed formation Ge a crystallite size 19 nm. FTIR SEM analysis verified successful incorporation HA into lattice. BET revealed increased porosity upon addition, indicating potential benefits for catalytic applications. efficiency was assessed methylene blue dye degradation as model reaction. Surprisingly, pristine exhibited an impressive 89.11% rate, greater than (6% 12%) HA‐modified photocatalysts. These findings highlight complex interaction between surface chemistry, porosity, activity.

Language: Английский

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Self-assembly of phosphorylated capsaicin and curcumin for treatment of triple-negative breast cancer via combination of chemotherapy and photodynamic therapy

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 137108 - 137108

Published: May 1, 2025

Language: Английский

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Surface Coating of ZIF‐8 Nanoparticles with Polyacrylic Acid: A Facile Approach to Enhance Chemical Stability for Biomedical Applications

Macromolecular Bioscience, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 3, 2024

Abstract Nanoparticles of zeolitic imidazole framework‐8 (ZIF‐8 NPs), which are the subclass metal‐organic frameworks consisting Zn ion and 2‐methylimidazole, have been identified as promising drug carriers since their large microporous structure is suited for encapsulating hydrophobic molecules. However, one limitations ZIF‐8 NPs low stability in physiological solutions, especially presence water phosphate anions. These molecules can interact with coordinatively unsaturated sites at external surface to induce degradation NPs. In this study, herein a facile approach reported enhance chemical by coating polyacrylic acid (PAA). The PAA‐coated (PAA‐ZIF‐8) prepared mixing PAA water. inhibits well phosphate‐buffered saline over 6 days, seems be due coordination carboxyl groups reactive sites. Furthermore, PAA‐ZIF‐8 loaded anticancer doxorubicin (Dox) show cytotoxicity human colon cancer cells. results clearly feasibility improve without impairing delivery capability.

Language: Английский

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Rationally Designed Porous Self-Assembled Nanoparticles for Combinational Chemo-Photodynamic Therapy

Dalton Transactions, Journal Year: 2024, Volume and Issue: 53(43), P. 17465 - 17479

Published: Jan. 1, 2024

Zinc-coordinated quercetin-based self-assembled nanoparticles (ZnQ NPs) further loaded with Ce6 enhance cancer treatment efficacy through combined chemotherapy and photodynamic therapy.

Language: Английский

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A systematic review on hyaluronic acid coated nanoparticles: recent strategy in breast cancer management

Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 42

Published: Oct. 21, 2024

Hyaluronic acid, a non-sulphated glycosaminoglycan has attracted its usage in the management of breast cancer. Drug-loaded nanoparticles with hyaluronic acid surface modifications show potential as promising method for targeting and delivering drugs to tumor site. The aim this study was conduct systematic review articles assess impact coated on various database were used comprehensive review. inclusion exclusion criteria selected according PRISMA guidelines. Studies associated characterization, vitro, vivo studies collected subjected further analysis. According criteria, 41 literature From all studies, it observed that produced better particle size, shape, zeta potential, increased vitro cytotoxicity, cellular uptake, cell apoptosis, anti-tumor effect vivo. Research shown exhibits higher affinity CD44 receptors, resulting enhanced targeted nanoparticle activity cancer cells while sparing normal cells.

Language: Английский

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