ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: 17(18), P. 26178 - 26190
Published: April 28, 2025
In the field of wound exudate management, Janus dressings with unidirectional fluid transport capabilities have garnered extensive attention. However, hydrophilic layer tends to be saturated during application, which often leads significant declines in drainage efficiency. To address this issue, study constructed a dressing hydrophilic-hydrophobic wettability gradient that could continuously evaporate layer. The nanofibers poly(vinyl alcohol)-MXene (PVA-MXene) were deposited onto hydrophobic nanofiber polyurethane-MXene (PU-MXene) by sequential electrospinning form asymmetric wettability. can enable from bed effectively prevent rewetting expelled biological fluid. incorporation MXene endows photothermal responsiveness, allowing it expel at stable evaporation rate and maintain moisture-unsaturated state. addition, effect imparts antibacterial activity infections. application using rat infection model under NIR irradiation, demonstrated anti-inflammatory effects, promoted collagen deposition angiogenesis, thus significantly accelerated healing process. Our offered an innovative approach development structure provided effective solution for management.
Language: Английский