Various Antibacterial Strategies Utilizing Titanium Dioxide Nanotubes Prepared via Electrochemical Anodization Biofabrication Method DOI Creative Commons

Wuzhi Wang,

Hanpeng Liu,

Zilin Guo

et al.

Biomimetics, Journal Year: 2024, Volume and Issue: 9(7), P. 408 - 408

Published: July 5, 2024

Currently, titanium and its alloys have emerged as the predominant metallic biomaterials for orthopedic implants. Nonetheless, relatively high post-operative infection rate (2-5%) exacerbates patient discomfort imposes significant economic costs on society. Hence, urgent measures are needed to enhance antibacterial properties of alloy The dioxide nanotube array (TNTA) is gaining increasing attention due topographical photocatalytic properties. Moreover, pores within TNTA serve excellent carriers chemical ion doping drug loading. fabrication surface can be achieved through various methods. Studies demonstrated that electrochemical anodization method offers numerous advantages, such simplicity, cost-effectiveness, controllability. This review presents development process applications in synthesizing TNTA. Additionally, this article systematically discusses topographical, chemical, delivery, combined strategies. It widely acknowledged implants should possess a range favorable biological characteristics. Clearly, addressing multiple needs with single strategy challenging. proposes systematic research into strategies further mitigate risks implant success rates future.

Language: Английский

Titanium-Based alloys and composites for orthopedic implants Applications: A comprehensive review DOI Creative Commons
Walaa Abd‐Elaziem, Moustafa A. Darwish, Atef Hamada

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: 241, P. 112850 - 112850

Published: March 13, 2024

The increasing demand for orthopedic implants has driven the search materials that combine strength, biocompatibility, and long lifetime. Compared to stainless steel Co-Cr-based alloys, titanium (Ti) its alloys are favored biomedical because of their high corrosion resistance, biocompatibility. This comprehensive review delivers a wide overview field titanium-based biomaterials applications, focusing on types, mechanical chemical surface modifications, innovations in fabrication techniques, matrix composites, machine learning advancements. Titanium different crystalline phases, including α, near-α, (α + β), β, shape memory offer diverse options applications. Strengthening properties, wear, fatigue, resistance crucial factors influencing performance reliability implants. Moreover, this discussed challenges biomaterial durability through modifications enhance biofunction, wear antibacterial properties. Recent developments techniques also discussed. Eventually, investigated how (ML) revolutionized by providing insights into behavior new aiding manufacturing optimization, allowing real-time quality control, advancing development personalized, biocompatible, reliable

Language: Английский

Citations

111

Towards load-bearing biomedical titanium-based alloys: From essential requirements to future developments DOI Creative Commons

Yuwei Cui,

Liqiang Wang, Lai‐Chang Zhang

et al.

Progress in Materials Science, Journal Year: 2024, Volume and Issue: 144, P. 101277 - 101277

Published: March 8, 2024

The use of biomedical metallic materials in research and clinical applications has been an important focus a significant area interest, primarily owing to their role enhancing human health extending lifespan. This article, particularly on titanium-based alloys, explores exceptional properties that can address bone issues amid the growing challenges posed by aging population. Although stainless steel, magnesium-based cobalt-based other are commonly employed medical applications, limitations such as toxic elements, high elastic modulus, rapid degradation rates limit widespread applications. Therefore, alloys have emerged top-performing materials, gradually replacing counterparts various article extensively examines highlights along with in-depth discussion currently utilized inherent limitations. To begin with, essential requirements for load-bearing biomaterials introduced. Then, summarized compared. Afterward, microstructure, properties, preparations explored. Furthermore, surface modification methods discussed enhance biocompatibility, wear resistance corrosion resistance. Finally, proposes development path conjunction additive manufacturing novel alloy nitinol.

Language: Английский

Citations

81

Emerging Strategies to Prevent Bacterial Infections on Titanium‐Based Implants DOI Creative Commons
Martin Villegas, Fereshteh Bayat, Taylor Kramer

et al.

Small, Journal Year: 2024, Volume and Issue: 20(46)

Published: Aug. 19, 2024

Titanium and titanium alloys remain the gold standard for dental orthopedic implants. These materials are heavily used because of their bioinert nature, robust mechanical properties, seamless integration with bone. However, implant-associated infections (IAIs) one leading causes implant failure. Eradicating an IAI can be difficult since bacteria form biofilms on medical implant, protecting bacterial cells against systemic antibiotics host's immune system. If infection is not treated promptly aggressively, device failure inevitable, to costly multi-step revision surgeries. To circumvent this dire situation, scientists engineers continue develop novel strategies protect surface implants from bacteria. In review, details emerging prevent in reported. include anti-adhesion properties provided by polymers, superhydrophobic, superhydrophilic, liquid-infused coatings, as well coatings employed lyse Additionally, commercially available technologies those under preclinical trials examined while discussing current future trends.

Language: Английский

Citations

11

Microstructure and anti-ablation of laser cladding Ti-Zr-B-C coating on TC11 titanium alloy DOI
Xiaojun Zhao,

Shanfeng Fang,

Peisheng Lyu

et al.

Journal of Alloys and Compounds, Journal Year: 2024, Volume and Issue: 990, P. 174498 - 174498

Published: April 12, 2024

Language: Английский

Citations

10

Growth factor-functionalized titanium implants for enhanced bone regeneration: A review DOI

Zhenjia Che,

Qi Sun, Zhenyu Zhao

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 274, P. 133153 - 133153

Published: June 17, 2024

Language: Английский

Citations

9

Effects of Shot Peening and Electropolishing Treatment on the Properties of Additively and Conventionally Manufactured Ti6Al4V Alloy: A Review DOI Open Access
Wojciech Okuniewski, Mariusz Walczak, Mirosław Szala

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(4), P. 934 - 934

Published: Feb. 17, 2024

This literature review indicates that the basic microstructure of Ti6Al4V is bimodal, consisting two phases, namely α + β, and it occurs after fabrication using conventional methods such as casting, plastic forming or machining processes. The components via an additive manufacturing process significantly changes properties Ti6Al4V. Due to rapid heat exchange during treatment, bimodal transforms into a lamellar microstructure, which consists phases: α' β. Despite application optimum printing parameters, 3D printed products exhibit typical surface defects discontinuities, in turn, finishing shot peening recommended. A signalizes electropolishing processes positively impact corrosion behavior, mechanical condition layer conventionally manufactured titanium alloy. On other hand, there lack studies combining one hybrid for additively alloys, could synthesize benefits both Therefore, this paper clarifies effects treatment on alloys shows effect

Language: Английский

Citations

8

Effect of Al/Cu Ratio on Microstructure and High-Temperature Oxidation Resistance of AlxCoCrCuyFeNi High-Entropy Alloy Coatings DOI Creative Commons
Ling Zhou, Hongxi Liu, Qinghua Zhang

et al.

Journal of Manufacturing and Materials Processing, Journal Year: 2025, Volume and Issue: 9(1), P. 13 - 13

Published: Jan. 5, 2025

To improve high-temperature oxidation resistance for Ti6Al4V alloy, AlxCoCrCuyFeNi (x = 0, 0.3, 0.5, 0.7, 1.0; y 1.0, x + 1.0) high-entropy alloy (HEA) coatings were prepared on the substrate by a laser cladding technique. The results show that mainly composed of FCC, BCC, and Ti-rich phases. Severe segregation Cu element occurred in CoCrCuFeNi HEA as Cu-rich phase (FCC2). phases decreased with decreasing content completely disappeared until Al reached 1.0. microhardnesses Cu1.0, Cu0.7Al0.3, Cu0.5Al0.5, Cu0.3Al0.7, Al1.0 2.01, 2.06, 2.08, 2.09, 2.11 times substrate, compared those rates 55%, 51%, 47%, 42%, 35%, respectively. surface oxides five CuO, TiO2, Fe3O4, Cr2O3, Al2O3. increase promoted generation Al2O3 film Cr2O3 surfaces coatings, which significantly improved antioxidant performance 50 h at 800 °C. When coating showed best performance.

Language: Английский

Citations

1

Surface-modified titanium and titanium-based alloys for improved osteogenesis: A critical review DOI Creative Commons
Jingling Li, Yaxin Zheng,

Zihe Yu

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 10(1), P. e23779 - e23779

Published: Dec. 18, 2023

Language: Английский

Citations

21

A functional mineralized collagen hydrogel to promote angiogenic and osteogenic for osseointegration of 3D-printed titanium alloy microporous scaffolds DOI

Xiao Min Sheng,

Zhenjia Che,

Hongqing Qiao

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 133806 - 133806

Published: July 10, 2024

Language: Английский

Citations

7

Construction of strain responsive Ti-containing carboxymethyl cellulose hydrogel with transitional coordination precursor DOI
Congcong Wang, Jingjing Zhang,

Qian Fu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129865 - 129865

Published: Jan. 30, 2024

Language: Английский

Citations

6