Multifunctional Mesoporous Polydopamine Nanoplatforms for Synergistic Photothermal-Chemotherapy and Enhanced Immunotherapy in Breast Cancer Treatment DOI

Siqiong Wu,

Yongjun Chen,

Ke Wang

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 248, P. 114483 - 114483

Published: Dec. 27, 2024

Language: Английский

Self-Assembled Gd/Cyanine Nanoplatform for Magnetic Resonance Imaging Guided Photothermal Therapy of Thyroid Cancer DOI

Changzhi Guo,

Fulin Li, Shuang Wu

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Language: Английский

Citations

0
A ZIF-8 nano drug delivery system that inhibits protective autophagy in cancer cells for enhancing photothermal antitumor therapy DOI

Yu Sun,

Jianfang Cen,

Liyun Yang

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106954 - 106954

Published: April 1, 2025

Language: Английский

Citations

0
Application of zeolitic imidazolate frameworks-8 in drug delivery and disease therapy: A review DOI
Sihan Ma,

Heyi Gong,

Mengyuan Jiang

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: unknown, P. 113835 - 113835

Published: Dec. 1, 2024

Language: Английский

Citations

2
Halogen atom regulation of acceptor–donor–acceptor type conjugated molecules for photothermal antibacterial and antibiofilm therapy DOI
Yue Zhao, Yuanyuan Cui,

Shijie Xie

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(17), P. 4386 - 4392

Published: Jan. 1, 2024

Drug-resistant bacteria and biofilm have caused serious public health problems. It is necessary to develop a treatment that highly effective against drug-resistant without inducing drug resistance. Herein, we prepare series of nanoparticles based on three conjugated molecules (BTP-BrCl, BTP-ClBr, BTP-ClmBr) with acceptor-donor-acceptor (A-D-A) structure. By adjusting the position halogen atoms, photothermal properties can be effectively regulated. In particular, these BTP-ClmBr NPs) exhibited conversion efficiencies (PCE) up 57.4%, 60.3%, 75.9%, respectively. Among nanoparticles, NPs chlorine atom close carbonyl bromine away from in acceptor highest PCE. Due their excellent properties, all achieved more than 99.9% antibacterial activity AmprE. coli, S. aureus MRSA. When was treated under light irradiation, little formation observed. Moreover, they could kill biofilm. summary, this study provides strategy for preparation high-performance nano-photothermal agents application field anti-drug resistant prevention cure.

Language: Английский

Citations

1
Recent Progress in Photothermal, Photodynamic and Sonodynamic Cancer Therapy: Through the cGAS-STING Pathway to Efficacy-Enhancing Strategies DOI Creative Commons

Kelan Fang,

Huiling Zhang, Qinghong Kong

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3704 - 3704

Published: Aug. 5, 2024

Photothermal, photodynamic and sonodynamic cancer therapies offer opportunities for precise tumor ablation reduce side effects. The cyclic guanylate adenylate synthase-stimulator of interferon genes (cGAS-STING) pathway has been considered a potential target to stimulate the immune system in patients achieve sustained response. Combining photothermal, with cGAS-STING agonists represents newly developed treatment demonstrating noticeable innovation its impact on system. Recent reviews have concentrated diverse materials their function therapy. In this review, we focus molecular mechanism connected role treating cancer.

Language: Английский

Citations

1
Precise Photothermal Treatment of Bacterial Infection Mediated by Charge-Switchable Nanoplatform with Acylsulfonamide Betaine Surface DOI

Wenyuan Sun,

Shumin Hu,

Binzhong Lu

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 245, P. 114362 - 114362

Published: Nov. 5, 2024

Language: Английский

Citations

1
NIR-induced antimicrobial efficacy of TPA-BOIMPY conjugate through photothermal and photodynamic synergy DOI
Worakrit Saiyasombat,

Sineenat Sripattanakul,

Sastiya Kampaengsri

et al.

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 460, P. 116136 - 116136

Published: Nov. 12, 2024

Language: Английский

Citations

1
Fabrication of acorn-shaped Janus C-SiO2 carrier and their application in DOX release DOI
Yan Wang, Jiaqi Lu,

Menghui Wan

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 100, P. 106137 - 106137

Published: Aug. 29, 2024

Language: Английский

Citations

0
Polydopamine-Functionalized Calcium-Deficient Hydroxyapatite 3D-printed Scaffold with Sustained Doxorubicin Release for Synergistic Chemo-Photothermal Therapy of Osteosarcoma and Accelerated Bone Regeneration DOI Creative Commons
Lu Wang, Zihan Dai,

Jianqiang Bi

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101253 - 101253

Published: Sept. 25, 2024

Interior bone-tissue regeneration and rapid tumor recurrence post-resection are critical challenges in osteosarcoma other bone cancers. Conventional tissue engineering scaffolds lack inhibitory effects on recurrence. Herein, multifunctional (named DOX/PDA@CDHA) were designed through the spontaneous polymerization of Dopamine (PDA) surface Calcium Deficient Hydroxyapatite (CDHA) scaffolds, followed by situ loading chemotherapeutic drug Doxorubicin (DOX). The PDA coating endowed with significant photothermal properties, while gradual release DOX provided an effective effect. on-demand at sites, triggered dual stimulation (near-infrared (NIR) light acidic pH typical microenvironments), specifically targets cancer cells, thereby mitigating systemic side effects. These unique characteristics facilitated eradication both vitro vivo. Moreover, scaffold's composition, which mimics mineral phase natural is enhanced PDA's biocompatibility, promotes osteogenic angiogenic processes. This facilitates not only but also healthy tissue. Collectively, this study presents a potent candidate for defects induced osteosarcoma.

Language: Английский

Citations

0
Drug-Delivery Based on Encapsulation for Photodynamic Therapy and Photothermal Therapy DOI Creative Commons
María Paulina Romero, Michel Gonzalez

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 16, 2024

Photodynamic therapy (PDT) and photothermal (PTT) have shown significant promise in treating cancer other illnesses. Photosensitizers (PSs) agents (PTAs) play crucial roles PDT PTT to enhance treatment efficiently. The stability, solubility, toxicity of PSs PTAs are the main challenges improving effectiveness these agents. This chapter examines several encapsulation techniques PS reduce limitations. Liposomes, hydrogels, inorganic particles, metal-organic frameworks, covalent organic frameworks offer diverse important strategies for PS, agents’ delivery. These nanocarrier systems unique advantages such as high efficiency, sustained drug release, enhanced cytotoxicity against cells, biocompatibility. Moreover, nanocapsules create a localized depot at target site present specific benefits tailored requirements different therapeutic applications, making them valuable tools developing advanced targeted delivery diseases. Overall, encapsulating photosensitizers enhancing efficacy safety PTT, promising candidates applications.

Language: Английский

Citations

0