Enhanced Osteogenic Activity of a Titanium Mesh Modified with Magnesium-Doped Nanowires for Peri-Implant Guided Bone Regeneration: In Vitro and In Vivo DOI

Zhe Shen,

Yawen Zhu,

Yu-wen Wei

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Titanium mesh is a promising barrier membrane for the reconstruction of alveolar bone defects, with quality and volume being critical factors impacting initial stability success rate implants. The objective this study to integrate bioactive magnesium ions nanowire structures into titanium surface (Mg-NW-Ti) further investigate its characteristics osteogenic bioactivity in vitro vivo. Mg-NW-Ti was effectively synthesized through series chemical reactivity tests, morphology, roughness, hydrophilicity, elemental composition, ion release were characterized. biological effects on MC3T3-E1 cells assessed compared commercially pure (CP-Ti) nanowire-modified (NW-Ti). In addition, peri-implant defect model rabbit mandibular constructed evaluate regeneration osseointegration implant. resultant Ti appeared as structure under scanning electron microscopy higher roughness hydrophilicity CP-Ti. X-ray photoelectron spectroscopy analysis demonstrated successful loading onto effective surroundings. exhibited good biocompatibility significantly enhanced proliferation differentiation MC3T3-E1, while results vivo that beneficial impact implant osseointegration. conclusion, novel modification may serve an strategy optimizing functionality harnessing potential increased application value.

Language: Английский

Study of Impact Behavior of Glass-Fiber-Reinforced Aluminum Composite Sandwich Panels at Constant Energy Levels DOI Open Access
Ercan Şi̇mşi̇r

Coatings, Journal Year: 2025, Volume and Issue: 15(3), P. 299 - 299

Published: March 4, 2025

In this investigation, we assessed the potential of aluminum composite panels (ACPs) in sustainable engineering applications, focusing on effects different glass fiber weights impact resistance and energy absorption capacity. Aluminum are an attractive option for applications due to their lightweight high-strength properties. study, low-velocity tests were conducted with 200 g/m2 400 equal numbers layers. The performed using a constant 55 joules, force–time, force–displacement, energy–time, energy–displacement behaviors ACP, ACP samples analyzed. results showed that exhibited highest strength, capacity, least damage. contrast, other two lower breaks, delaminations, core material damage surfaces. used study contributed increases Positive correlations found between weight, layer thickness, strength. These findings provide new insights into how materials can be designed optimize mechanical properties by adjusting coatings. also offer valuable information development next-generation various fields, such as automotive vehicle technology.

Language: Английский

Citations

2
Advances in osteoimmunomodulation of biomaterials after intrabone implantation: Focus on surface hydrophilicity DOI
Xinpeng Wei,

Linshan Lei,

Ling Luo

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Biomaterials intended for intrabone implantation are extensively utilized in orthopedic and dental applications. Their surface properties, particularly hydrophilicity, significantly influence the biological interactions surrounding implant, ultimately determining implant's

Language: Английский

Citations

5
Enhanced Osteogenic Activity of a Titanium Mesh Modified with Magnesium-Doped Nanowires for Peri-Implant Guided Bone Regeneration: In Vitro and In Vivo DOI

Zhe Shen,

Yawen Zhu,

Yu-wen Wei

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Titanium mesh is a promising barrier membrane for the reconstruction of alveolar bone defects, with quality and volume being critical factors impacting initial stability success rate implants. The objective this study to integrate bioactive magnesium ions nanowire structures into titanium surface (Mg-NW-Ti) further investigate its characteristics osteogenic bioactivity in vitro vivo. Mg-NW-Ti was effectively synthesized through series chemical reactivity tests, morphology, roughness, hydrophilicity, elemental composition, ion release were characterized. biological effects on MC3T3-E1 cells assessed compared commercially pure (CP-Ti) nanowire-modified (NW-Ti). In addition, peri-implant defect model rabbit mandibular constructed evaluate regeneration osseointegration implant. resultant Ti appeared as structure under scanning electron microscopy higher roughness hydrophilicity CP-Ti. X-ray photoelectron spectroscopy analysis demonstrated successful loading onto effective surroundings. exhibited good biocompatibility significantly enhanced proliferation differentiation MC3T3-E1, while results vivo that beneficial impact implant osseointegration. conclusion, novel modification may serve an strategy optimizing functionality harnessing potential increased application value.

Language: Английский

Citations

0