Zooming in and Out of Programmed Cell Death in Osteoarthritis: A Scientometric and Visualized Analysis

Journal of Inflammation Research, Journal Year: 2024, Volume and Issue: Volume 17, P. 2479 - 2498

Published: April 1, 2024

During the past decade, mounting evidence has increasingly linked programmed cell death (PCD) to progression and development of osteoarthritis (OA).There is a significant need for thorough scientometric analysis that recapitulates relationship between PCD OA.This study aimed collect articles reviews focusing on in OA, extracting data from January 1st, 2013, October 31st, 2023, using Web Science.Various tools, including VOSviewer, CiteSpace, Pajek, Scimago Graphica, R package, were employed visualization analyses.Notably, China, USA, South Korea emerged as major contributors, collectively responsible more than 85% published papers significantly influencing research this field.Among different institutions, Shanghai Jiao Tong University, Xi'an Zhejiang University exhibited highest productivity.Prolific authors included Wang Wei, Jing, Zhang Li

Language: Английский

---

Targeting ferroptosis unveils a new era for traditional Chinese medicine: a scientific metrology study

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Feb. 14, 2024

In the past 11 years, there has been a surge in studies exploring regulatory effect of Traditional Chinese Medicine (TCM) on ferroptosis. However, significant gap persists comprehensive scientometric analysis and scientific mapping research, especially tracking evolution, primary contributors, emerging research focal points. This study aims to comprehensively update advancements targeting ferroptosis with various TCMs during previous years. The data, covering period from 1 January 2012, 30 November 2023, were retrieved Web Science database. For in-depth visualized analyses, series advanced analytical instruments employed. findings highlight China’s predominant role, accounting for 71.99% total publications significantly shaping this domain. Noteworthy productivity was observed at institutions, including Guangzhou University Medicine, Chengdu Zhejiang University. Thomas Efferth emerged as foremost author within field, while Frontiers Pharmacology boasted highest publication count. pinpointed hepatocellular carcinoma, chemical drug-induced liver injury, mitochondrial diseases, acute kidney failure most critical disorders addressed realm. offers bibliometric evaluation, enhancing our understanding present status TCM therapy managing ferroptosis-related diseases. Consequently, it aids both seasoned researchers newcomers by accelerating access vital information fostering innovative concept extraction specialized field.

Language: Английский

---

A bibliometric worldview of breast-conserving surgery for breast cancer from 2013 to 2023

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: July 19, 2024

Over the last decade, significant advancements have been made in breast-conserving surgery (BCS) for breast cancer. However, there is a lack of analytical and descriptive investigations on trajectory, essential research directions, current scenario, pivotal investigative focuses, forthcoming perspectives. The objective this to provide thorough update progress BCS cancer over preceding decade. Retrieved from Web Science database, data span January 1, 2013, November 30, 2023. Utilizing set advanced instruments, we conducted comprehensive bibliometric visual analyses. findings underscore predominant influence USA, representing 35.77% overall publications playing role shaping within field. Notable productivity was evident at various institutions, including Memorial Sloan Kettering Cancer Center, University Texas MD Anderson Toronto.

Language: Английский

---

Uncovering the Scientific Landscape: A Bibliometric and Visualized Analysis of Artificial Intelligence in Traditional Chinese Medicine

Heliyon, Journal Year: 2024, Volume and Issue: unknown, P. e37439 - e37439

Published: Sept. 1, 2024

Language: Английский

---

Mapping the evolution and research landscape of ferroptosis-targeted nanomedicine: insights from a scientometric analysis

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 25, 2024

Notable progress has been made in "ferroptosis-based nano drug delivery systems (NDDSs)" over the past 11 years. Despite ongoing absence of a comprehensive scientometric overview and up-to-date scientific mapping research, especially regarding evolution, critical research pathways, current landscape, central investigative themes, future directions.

Language: Английский

---

A scientometric and visualization analysis of 3D printing scaffolds for vascularized bone tissue engineering over the last decade

Regenerative Therapy, Journal Year: 2024, Volume and Issue: 26, P. 1099 - 1116

Published: June 1, 2024

Language: Английский

---

Bioactive MgO/MgCO3/Polycaprolactone Multi-gradient Fibers Facilitate Peripheral Nerve Regeneration by Regulating Schwann Cell Function and Activating Wingless/Integrase-1 Signaling

Advanced Fiber Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 8, 2024

Abstract Peripheral nerve defects present complex orthopedic challenges with limited efficacy of clinical interventions. The inadequate proliferation and dysfunction Schwann cells within the scaffold impede effectiveness repair. Our previous studies suggested a magnesium-encapsulated bioactive hydrogel in repairing defects. However, its rapid release magnesium ions to long-term regeneration, molecular mechanism remains unclear. This study utilized electrospinning technology fabricate MgO/MgCO 3 /polycaprolactone (PCL) multi-gradient nanofiber membrane for peripheral regeneration. findings indicated that by carefully adjusting concentration or proportion rapidly degradable MgO slowly MgCO , as well number electrospun layers, effectively sustained Mg 2+ over period 6 weeks. Additionally, this provided insight into -induced regeneration confirmed promoted cell proliferation, migration, transition repair phenotype. By employing transcriptome sequencing technology, identified Wingless/integrase-1 (Wnt) signaling pathway crucial influencing function during After implantation 10 mm critically sized rats, /PCL combined 3D-engineered PCL conduit showed enhanced axonal remyelination, reinnervation muscle tissue 12 weeks post-surgery. In conclusion, successfully developed an innovative long-acting tunable property, which underscored biomaterials treating nervous system diseases established robust theoretical foundation future translation. Graphical abstract

Language: Английский

---

Multilabel classification for defect prediction in software engineering

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 13, 2025

With advancements in software development and artificial intelligence, defect prediction has gradually become an essential component of the lifecycle. Historically, been considered a multiclass classification problem because classes are mutually exclusive. However, defects can belong to multiple categories simultaneously, making multilabel more appropriate approach. A report typically contains title, body, comments from developers testers, code snippets. We used these data items performed wrangling on create holistic summary report, which all vital information that is useful for predictions. In this study, we investigated dimension using machine learning deep techniques while considering class imbalance correlations between labels. traditional methods, three classifiers: Multinomial Naive Bayes, Logistic Regression, Random Forest. Multilayer Perceptron (MLP) Convolutional Neural Network (CNN) with Classifier Chains learning. To check dataset quality, feature selection, dimensionality reduction, chi-square test. handle imbalance, Non-Negative Least Squares (NNLS). Our experimental investigations showed significant improvements model performance across once was balanced before training models. Visual plots evaluation metrics, such as Hamming loss, Recall, Precision, F1-score, clearly demonstrated analysis outcome.

Language: Английский

---

The stealth effect from a medicinal chemist perspective: definition and updates

Frontiers in Drug Delivery, Journal Year: 2025, Volume and Issue: 5

Published: April 28, 2025

In recent years, there has been a significant increase in literature on emerging nanotechnologies, including nanoparticles, nanorobots, and exosomes, for various therapeutic applications. Additionally, politically driven research initiatives aimed at accelerating COVID-19 vaccine development have further amplified interest nanoparticles as drug delivery systems. This article provides personal perspective the scientific claims surrounding by: (i) analyzing historical evolution of their terminology, (ii) reviewing most cited publications field, (iii) offering professional assessment to guide next-generation medicinal chemists. A key aspect this discussion is stealth effect, which refers ability evade recognition clearance by immune system, thereby prolonging circulation time bloodstream. property essential enhancing efficacy nanoparticle-based therapeutics improving bioavailability ensuring targeted diseased tissues. Furthermore, continuing improvement ligand-molecules other functional tools developed novel strategies brand-new definition systems, such Trojan Horse Nanorobots.

Language: Английский

---

Global research trends on the links between prostate cancer and postoperative urinary incontinence between 2014 and 2024: a bibliometrics and visualized study

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: May 24, 2025

In recent years, the incidence of prostate cancer (PC) has increased. For patients suitable for surgery, surgical treatment is undoubtedly first-choice. However, radical prostatectomy often leads to postoperative urinary incontinence. As a result, issue incontinence following also come into focus. comprehensive and objective research on overall state UI after PC remains scarce. This article aims utilize bibliometrics summarize quantify dynamic trends in PC. We retrieved relevant literature from Web Science Core Collection database, spanning January 1, 2014, September 8, 2024, analyzed bibliometric indicators such as number articles, journals, countries, institutions, authors, keywords. A total 2060 articles were included, study shows continuous growth publications related UI, with United States leading this field. The Memorial Sloan Kettering Cancer Center institution highest output, journal "Urology" published most author Matthew R Cooperberg output. recommend active collaboration between authors conduct clinical basic research. Keyword analysis indicates that current primarily focused side effects treatment, application artificial sphincters, multiparametric magnetic resonance imaging field UI. anticipate caused by will continue be hot topic future It admitted our only included English there may some selection bias.

Language: Английский

---