Water modulated influence of intramolecular hydrogen-bonding on the conformational properties of Canabidiol (CBD)
Journal of Molecular Liquids,
Journal Year:
2025,
Volume and Issue:
unknown, P. 127033 - 127033
Published: Jan. 1, 2025
Language: Английский
High-Pressure Dielectric Spectroscopic Studies of Amorphous CBD: Investigating Molecular Dynamics and Physical Stability Under Manufacturing Conditions of the Pharmaceuticals
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(3), P. 358 - 358
Published: March 11, 2025
Objectives:
This
study
highlighted
the
key
role
played
by
high-pressure
(HP)
dielectric
spectroscopic
measurements
of
amorphous
CBD
to
probe
molecular
dynamics
in
order
examine
physical
stability
drug.
The
pharmacological
properties
assure
that
this
can
be
a
promising
drug
for
pharmaceutical
industry.
Hence,
it
is
important
check
under
elevated
temperature
and
pressure
conditions
understand
behavior
manufacturing
conditions.
Methods:
research
investigated
at
various
temperatures
pressures.
We
utilized
HP
studies
which
are
considered
as
an
advanced
sensitive
tool
determine
both
phase
transformations.
Results:
paper
discusses
analyzing
structural
relaxation
crystallization
tendencies
ambient
verified
highly
physically
stable
storage
pressure.
Conclusions:
Accordingly,
we
examined
pressures
temperature,
observed
compression
induced
CBD.
breaking
weak
hydrogen
bonds
present
might
reason
destabilization
least
was
also
confirmed
broadening
α-relaxation
peak
high
Language: Английский
Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, and functionality
Critical Reviews in Food Science and Nutrition,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 23
Published: Dec. 9, 2024
Cannabidiol
(CBD)
in
industrial
hemp
is
a
promising
functional
food
ingredient
with
multifarious
health
benefits,
including
anticancer
activity,
antioxidant
anti-inflammatory
properties,
and
anxiolytic
effects.
In
recent
years,
the
application
of
CBD
industry
has
been
emerging
several
fortified
products
are
available
across
globe.
Currently,
scientific
information
associated
segregated,
there
lack
connectivity
between
their
explorations.
Therefore,
this
review,
findings
that
crucial
for
extending
its
applications
comprehensively
discussed.
It
begins
by
exploring
global
regulatory
landscape
CBD.
Followingly,
factors
affect
production
field,
isolation
techniques
from
flowers,
properties
detailed.
Importantly,
review
examines
reported
delivery
systems
enhancing
physicochemical
bioavailability
CBD,
thus
broadening
potential
industry.
Overall,
would
connect
patches
field
to
be
resourceful
scientists,
agencies,
farmers.
Language: Английский