Continuous integration of heading and goal directions guides steering DOI Creative Commons
Anthony M. Crown,

Annie H. Wu,

Lindsey Hofflander

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 26, 2024

Navigating animals must integrate a diverse array of sensory cues into single locomotor decision. Insects perform intricate navigational feats using brain region termed the central complex in which an animal's heading direction is transformed through several layers circuitry to elicit goal-directed locomotion. These transformations occur mostly fan-shaped body (FB), major locus multi-sensory integration complex. Key aspects these sensorimotor computations have been extensively characterized by functional studies, leveraging genetic tools available fruit fly. However, our understanding how neuronal activity FB dictates behaviors during navigation remains enigmatic. Here, we manipulate two key populations that input FB-the PFN

Language: Английский

Organization of an ascending circuit that conveys flight motor state in Drosophila DOI Creative Commons
Han SJ Cheong,

Kaitlyn Nicole Boone,

Marryn M. Bennett

et al.

Current Biology, Journal Year: 2024, Volume and Issue: 34(5), P. 1059 - 1075.e5

Published: Feb. 22, 2024

Language: Английский

Citations

15
Theory of morphodynamic information processing: Linking sensing to behaviour DOI Creative Commons
Mikko Juusola, Jouni Takalo, Joni Kemppainen

et al.

Vision Research, Journal Year: 2025, Volume and Issue: 227, P. 108537 - 108537

Published: Jan. 4, 2025

The traditional understanding of brain function has predominantly focused on chemical and electrical processes.However, new research in fruit fly (Drosophila) binocular vision reveals ultrafast photomechanical photoreceptor movements significantly enhance information processing, thereby impacting a fly's perception its environment behaviour.The coding advantages resulting from these mechanical processes suggest that similar physical motion-based strategies may affect neural communication ubiquitously.The theory morphodynamics proposes rapid biomechanical microstructural changes at the level neurons synapses speed efficiency sensory intrinsic thoughts, actions by regulating phasic manner.We propose morphodynamic processing evolved to drive predictive coding, synchronising cognitive across networks match behavioural demands hand effectively.

Language: Английский

Citations

1
Taking flight, the use of Drosophila melanogaster for neuroscience research in Uruguay DOI
Gonzalo Budelli, M.J. Ferreiro, Carmen Bolatto

et al.

Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
A rotational velocity estimate constructed through visuomotor competition updates the fly’s neural compass DOI Creative Commons
Brad K. Hulse, Angel Stanoev, Daniel B. Turner‐Evans

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 26, 2023

Abstract Navigating animals continuously integrate velocity signals to update internal representations of their directional heading and spatial location in the environment. How neural circuits combine sensory motor information construct these estimates how self-motion signals, turn, that support navigational computations are not well understood. Recent work Drosophila has identified a circuit performs angular path integration compute fly’s head direction, but nature signal is unknown. Here we identify pair neurons necessary for encode rotational with high accuracy using both visual optic flow information. This estimate does rely on moment-to-moment Rather, when congruent, prioritize over information, two conflict, reciprocal inhibition selects either or signal. Together, our results suggest flies direction representation by constructing an relies primarily only incorporates specific sensorimotor contexts, such as absent.

Language: Английский

Citations

10
Editorial overview: Computational neuroscience as a bridge between artificial intelligence, modeling and data DOI
Pietro Verzelli, Tatjana Tchumatchenko, Jeanette Hellgren Kotaleski

et al.

Current Opinion in Neurobiology, Journal Year: 2024, Volume and Issue: 84, P. 102835 - 102835

Published: Jan. 6, 2024

Language: Английский

Citations

3
Sexual dimorphism and the impact of aging on ball rolling associated locomotor behavior in Drosophila DOI Creative Commons

Gupta Soyam,

Nisha N. Kannan

Biology Open, Journal Year: 2024, Volume and Issue: 13(11)

Published: Oct. 22, 2024

ABSTRACT Insects exhibit a remarkable ability to interact with inanimate objects facilitate essential behaviors such as foraging, reproduction, shelter building, and defense. In this study, we assessed whether Drosophila interacted when they were suspended on their wings provided thermocol ball (foam ball). indeed exhibited rolling behavior. We further examined the sexual dimorphism in rolling-associated locomotor carried out assay using 3-day-old male female w1118 flies measured duration for which could roll without dropping it within 10 min period. The was returned whenever dropped it, calculated number of times duration. Females longer holding than males. also observed decrease an increase by 15-day-old younger counterparts. These results suggest age-dependent alterations

Language: Английский

Citations

2
Continuous integration of heading and goal directions guides steering DOI Creative Commons
Anthony M. Crown,

Annie H. Wu,

Lindsey Hofflander

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 26, 2024

Navigating animals must integrate a diverse array of sensory cues into single locomotor decision. Insects perform intricate navigational feats using brain region termed the central complex in which an animal's heading direction is transformed through several layers circuitry to elicit goal-directed locomotion. These transformations occur mostly fan-shaped body (FB), major locus multi-sensory integration complex. Key aspects these sensorimotor computations have been extensively characterized by functional studies, leveraging genetic tools available fruit fly. However, our understanding how neuronal activity FB dictates behaviors during navigation remains enigmatic. Here, we manipulate two key populations that input FB-the PFN

Language: Английский

Citations

0