Neuropsychiatric drug development: Perspectives on the current landscape, opportunities and potential future directions DOI Creative Commons
Simon Loïodice, Fulvio D’Acquisto,

Pim Drinkenburg

et al.

Drug Discovery Today, Journal Year: 2024, Volume and Issue: 30(1), P. 104255 - 104255

Published: Nov. 29, 2024

Language: Английский

Naturalistic computational psychiatry: How to get there? DOI Open Access
Lena Palaniyappan, Alban Voppel, Holly Wei

et al.

Journal of Psychiatry and Neuroscience, Journal Year: 2025, Volume and Issue: 50(1), P. E67 - E72

Published: Feb. 7, 2025

> Consider the practical effects of objects your conception. Then, conception those is whole object. — Charles Sanders Peirce[1][1] Each us has an individual mental phenomenon that defines us. Some our differences and similarities

Language: Английский

Citations

0
What can neuroimaging of neuromodulation reveal about the basis of circuit therapies for psychiatry? DOI
S Hashimoto, Atsushi Fujimoto, Catherine Elorette

et al.

Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 50(1), P. 184 - 195

Published: Aug. 28, 2024

Language: Английский

Citations

2
From palm to practice: prescription digital therapeutics for mental and brain health at the National Institutes of Health DOI Creative Commons

Michele Ferrante,

Layla Esposito,

Luke E. Stoeckel

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 10, 2024

Prescription Digital Therapeutics (PDTs) are emerging as promising tools for treating and managing mental brain health conditions within the context of daily life. This commentary distinguishes PDTs from other Software Medical Devices (SaMD) explores their integration into treatments. We focus on research programs support National Institutes Health (NIH), discussing PDT supported by NIH's Institute Child Development (NICHD), Mental (NIMH), Aging (NIA). present a hierarchical natural language processing topic analysis NIH-funded digital therapeutics projects. delineate landscape across different disorders while highlighting opportunities challenges. Additionally, we discuss foundation PDTs, unique therapeutic approaches they employ, potential strategies to improve validity, reliability, safety, effectiveness. Finally, address collaborations necessary propel field forward, ultimately enhancing patient care through innovative solutions.

Language: Английский

Citations

0
Characterizing Behavioral Dynamics in Bipolar Disorder with Computational Ethology DOI Creative Commons
Zhanqi Zhang, Chien Chou,

Holden Rosberg

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

New technologies for the quantification of behavior have revolutionized animal studies in social, cognitive, and pharmacological neurosciences. However, comparable understanding human behavior, especially psychiatry, are lacking. In this study, we utilized data-driven machine learning to analyze natural, spontaneous open-field behaviors from people with euthymic bipolar disorder (BD) non-BD participants. Our computational paradigm identified representations distinct sets actions (

Language: Английский

Citations

0
Neuropsychiatric drug development: Perspectives on the current landscape, opportunities and potential future directions DOI Creative Commons
Simon Loïodice, Fulvio D’Acquisto,

Pim Drinkenburg

et al.

Drug Discovery Today, Journal Year: 2024, Volume and Issue: 30(1), P. 104255 - 104255

Published: Nov. 29, 2024

Language: Английский

Citations

0