Neurology Clinical Practice, Journal Year: 2025, Volume and Issue: 15(3)

Published: April 3, 2025

Functional motor disorder (FMD), a motor-dominant variant of functional neurologic disorder, is disabling condition associated with high health and social care resource use poor employment outcomes. Specialist physiotherapy presents possible treatment option, but there limited evidence for clinical effectiveness cost-effectiveness. Physio4FMD multicenter randomized controlled trial specialist FMD compared as usual (TAU). The aim the analysis was to conduct based on economic evaluation TAU. Eleven centers in England Scotland participants 1:1 or TAU (referral community physiotherapy). Participants completed EuroQoL EQ-5D-5L, Client Service Receipt Inventory, Work Productivity Activity Impairment Questionnaire at baseline, 6 months, 12 months. mean incremental cost per quality-adjusted life year (QALY) over months calculated from wider societal perspective. probability cost-effectiveness 95% CIs were using bootstrapping. included 247 (n = 141 physiotherapy, n 106 TAU). participant £646 (SD 72) £272 374) Including costs treatment, adjusted £3,814 (95% CI £3,194-£4,433) £3,670 £2,931-£4,410) TAU, £143 £-825 £1,112). There no significant difference QALYs 12-month duration (0.030, -0.007 0.067). QALY £4,133 an 86% being cost-effective £20,000 threshold. When broader such loss productivity taken into consideration, dominant (incremental cost: £-5,169, £-15,394 £5,056). costs. that particularly when are account. International Standard Randomised Controlled Trial registry, ISRCTN56136713.

Language: Английский