First Characterization of a Cyanobacterial Xi-Class Glutathione S-Transferase in Synechocystis PCC 6803 DOI Creative Commons

Fanny Marceau,

Marlène Lamothe‐Sibold,

Sandrine Farci

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1577 - 1577

Published: Dec. 20, 2024

Glutathione S-transferases (GSTs) are evolutionarily conserved enzymes crucial for cell detoxication. They viewed as having evolved in cyanobacteria, the ancient photosynthetic prokaryotes that colonize our planet and play a role its biosphere. Xi-class GSTs, characterized by their specific glutathionyl–hydroquinone reductase activity, have been observed prokaryotes, fungi plants, but not yet studied cyanobacteria. In this study, we analyzed presumptive GST, designated Slr0605, of unicellular model cyanobacterium Synechocystis PCC 6803. We report Slr0605 is homodimeric protein has genuine activity. Though essential growth under standard photoautotrophic conditions, it plays prominent protection against only benzoquinone, also cobalt-excess stress. Indeed, acts defense cobalt-elicited disturbances iron homeostasis, iron–sulfur cluster repair, catalase activity level reactive oxygen species, which all life.

Language: Английский

The diversity of physiology and metabolism in chlorophototrophic bacteria DOI
I. White, Daniel P. Canniffe, Andrew Hitchcock

et al.

Advances in microbial physiology/Advances in Microbial Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
New tools for effective production and long-term stabilization of microcystinase (MlrA) - a biotechnological perspective towards hepatotoxic microcystins remediation DOI Creative Commons
Jason Dexter, Barbara Klimczak, Antonia Łobodzińska

et al.

Biocatalysis and Agricultural Biotechnology, Journal Year: 2024, Volume and Issue: 61, P. 103347 - 103347

Published: Sept. 6, 2024

Language: Английский

Citations

0
Editorial overview: Plant synthetic biology DOI
Andrew D. Hanson, Cătălin Voiniciuc

Current Opinion in Biotechnology, Journal Year: 2024, Volume and Issue: 90, P. 103211 - 103211

Published: Sept. 27, 2024

Language: Английский

Citations

0
First Characterization of a Cyanobacterial Xi-Class Glutathione S-Transferase in Synechocystis PCC 6803 DOI Creative Commons

Fanny Marceau,

Marlène Lamothe‐Sibold,

Sandrine Farci

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1577 - 1577

Published: Dec. 20, 2024

Glutathione S-transferases (GSTs) are evolutionarily conserved enzymes crucial for cell detoxication. They viewed as having evolved in cyanobacteria, the ancient photosynthetic prokaryotes that colonize our planet and play a role its biosphere. Xi-class GSTs, characterized by their specific glutathionyl–hydroquinone reductase activity, have been observed prokaryotes, fungi plants, but not yet studied cyanobacteria. In this study, we analyzed presumptive GST, designated Slr0605, of unicellular model cyanobacterium Synechocystis PCC 6803. We report Slr0605 is homodimeric protein has genuine activity. Though essential growth under standard photoautotrophic conditions, it plays prominent protection against only benzoquinone, also cobalt-excess stress. Indeed, acts defense cobalt-elicited disturbances iron homeostasis, iron–sulfur cluster repair, catalase activity level reactive oxygen species, which all life.

Language: Английский

Citations

0