The Outputs of Molecular Sensors Detectable by Human Senses
Chemical Communications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Molecular
sensors
respond
to
the
presence
of
biological
analytes
by
producing
signals
that
are
either
directly
perceivable
human
sensory
systems
or
converted
into
electric
signals,
which
require
electronic
devices
for
communicating
humans.
Here,
we
review
outputs
molecular
detectable
senses.
According
literature,
with
visual
dominate.
Undeservedly
unnoticed,
release
gases
might
be
particularly
useful
since
gas
output
can
detected
several
senses
in
a
quantifiable
format.
Relatively
new
tactile
accessed
visually
impaired
people.
their
bypassing
may
contribute
development
point-of-care
testing
technologies,
as
well
providing
direct
communication
nanorobots
Language: Английский
Nanolevel of detection of ascorbic acid using horse-radish peroxidase inhibition assay
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(10), P. e30715 - e30715
Published: May 1, 2024
Ascorbic
acid
plays
a
significant
role
in
regulation
of
various
bodily
functions
with
high
concentrations
immune
cells
and
being
involved
connective
tissue
maintenance.
Commonly
it
is
detected
through
colorimetric
methods.
In
this
study,
we
propose
one-step
simple
method
based
on
the
inhibitory
activity
ascorbic
horseradish
peroxidase
hydrogen
peroxide.
The
detection
observed
by
changes
to
TMB
(3,3',5,5'
tetramethylbenzidine).
enzyme
inhibition
unit
was
optimized
level
linearity
(r
Language: Английский
Painting cell-cell interactions by horseradish peroxidase and endogenously generated hydrogen peroxide
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 13, 2024
ABSTRACT
Cell-Cell
interactions
are
fundamental
in
biology
for
maintaining
physiological
conditions,
with
direct
contact
being
the
most
straightforward
mode
of
interaction.
Recent
advancements
have
led
to
development
various
chemical
tools
detecting
or
identifying
these
interactions.
However,
use
exogenous
cues,
such
as
toxic
reagents,
bulky
probes,
and
light
irradiations,
can
disrupt
normal
cell
physiology.
For
example,
toxicity
hydrogen
peroxide
(H
2
O
)
limits
applications
peroxidases
proximity
labeling
field.
In
this
study,
we
aimed
address
limitation
by
demonstrating
that
membrane-localized
Horseradish
Peroxidase
(HRP-TM)
efficiently
utilizes
endogenously
generated
extracellular
H
.
By
harnessing
endogenous
,
observed
HRP-TM-expressing
cells
effectively
label
contacting
without
need
treatment.
Furthermore,
confirmed
HRP-TM
labels
proximal
an
interaction-dependent
manner.
These
findings
offer
a
novel
approach
studying
cell-cell
under
more
confounding
effects
stimuli.
Our
study
contributes
elucidating
interaction
networks
model
organisms,
providing
valuable
insights
into
dynamic
interplay
between
their
native
network.
Language: Английский
Painting Cell–Cell Interactions by Horseradish Peroxidase and Endogenously Generated Hydrogen Peroxide
ACS Chemical Biology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 18, 2024
Cell-cell
interactions
are
fundamental
in
biology
for
maintaining
physiological
conditions
with
direct
contact
being
the
most
straightforward
mode
of
interaction.
Recent
advancements
have
led
to
development
various
chemical
tools
detecting
or
identifying
these
interactions.
However,
use
exogenous
cues,
such
as
toxic
reagents,
bulky
probes,
and
light
irradiation,
can
disrupt
normal
cell
physiology.
For
example,
toxicity
hydrogen
peroxide
(H
Language: Английский
From Rainforest to Lab: Electrochemical Biosensing with Colombian Plant Peroxidases
Revista Colombiana de Biotecnología,
Journal Year:
2024,
Volume and Issue:
26(2), P. 77 - 96
Published: Dec. 11, 2024
The
peroxidases
are
a
class
of
enzymes
found
in
various
species
Colombian
tropical
plants.
These
belong
to
the
larger
group
peroxidases,
which
heme-containing
proteins
involved
catalysing
wide
range
reactions
living
organisms.
Peroxidases
have
emerged
as
promising
biocatalysts
with
versatile
biotechnological
applications.
This
paper
aims
provide
detailed
analysis
plants
and
their
potential
electrochemical
sensing.
review
begins
by
elucidating
structural
functional
characteristics
plants,
exploring
classification,
highlighting
catalytic
mechanisms.
It
then
delves
into
substrate
specificity
affinity
plant
its
comparison
other
peroxidases.
Furthermore,
diverse
techniques
relevant
biosensing
applications
biosensor
development
thoroughly
examined.
challenges
prospects
utilizing
critically
evaluated.
In
summary,
this
study
highlights
significance
valuable
bioanalytical
tool.
Their
multifaceted
environmental,
agricultural,
food,
pharmaceutical
bioanalysis
sectors
make
them
indispensable
addressing
contemporary
challenges.
insights
provided
herein
serve
foundation
for
future
research
endeavours
aimed
at
harnessing
full
construction
biosensors.
Language: Английский