High-level RNA editing diversifies the coleoid cephalopod brain proteome DOI
Gjendine Voss, Joshua J. C. Rosenthal

Briefings in Functional Genomics, Journal Year: 2023, Volume and Issue: 22(6), P. 525 - 532

Published: Aug. 9, 2023

Abstract Coleoid cephalopods (octopus, squid and cuttlefish) have unusually complex nervous systems. The coleoid system is also the only one currently known to recode majority of expressed proteins through A-to-I RNA editing. deamination adenosine by deaminase acting on (ADAR) enzymes produces inosine, which interpreted as guanosine during translation. If this occurs in an open reading frame, case for tens thousands editing sites coleoids, it can encoded protein. Here, we describe recent findings aimed at deciphering mechanisms underlying high-level recoding its adaptive potential. We complement ADAR cephalopods, including a recently discovered novel domain sqADAR1. further summarize current evidence supporting role review studies showing that large proportion temperature-sensitive. Despite these new findings, governing high level remain poorly understood. Recent advances using genome may provide useful tools study animals.

Language: Английский

Dynamic skin behaviors in cephalopods DOI Creative Commons

Erica N. Shook,

George Thomas Barlow,

Daniella Garcia-Rosales

et al.

Current Opinion in Neurobiology, Journal Year: 2024, Volume and Issue: 86, P. 102876 - 102876

Published: April 22, 2024

The coleoid cephalopods (cuttlefish, octopus, and squid) are a group of soft-bodied mollusks that exhibit wealth complex behaviors, including dynamic camouflage, object mimicry, skin-based visual communication, body patterns during sleep. Many these behaviors visually driven engage the animals' color changing skin, pixelated display is directly controlled by neurons projecting from brain. Thus, cephalopod skin provides direct readout neural activity in During recreate on their an approximation what they see, providing window into perceptual processes Additionally, communicate internal state social encounters using innate patterns, create waves pigmentation periods arousal. leveraging displays cephalopods, we can gain insight how external world represented brain this representation transformed recapitulation skin. Here, describe rich known about neuroanatomy, advancements gene editing, machine learning, optical imaging, electrophysiological tools may provide opportunity to explore bases fascinating behaviors.

Language: Английский

Citations

7
Creation of an albino squid line by CRISPR-Cas9 and its application for in vivo functional imaging of neural activity DOI
Namrata Ahuja, Ernie Hwaun, Judit R. Pungor

et al.

Current Biology, Journal Year: 2023, Volume and Issue: 33(13), P. 2774 - 2783.e5

Published: June 20, 2023

Language: Английский

Citations

15
A brain atlas for the camouflaging dwarf cuttlefish, Sepia bandensis DOI Creative Commons
Tessa G. Montague, Isabelle J. Rieth,

Sabrina Gjerswold-Selleck

et al.

Current Biology, Journal Year: 2023, Volume and Issue: 33(13), P. 2794 - 2801.e3

Published: June 20, 2023

The coleoid cephalopods (cuttlefish, octopus, and squid) are a group of soft-bodied marine mollusks that exhibit an array interesting biological phenomena, including dynamic camouflage, complex social behaviors, prehensile regenerating arms, large brains capable learning, memory, problem-solving.1Turchetti-Maia A. Shomrat T. Hochner B. vertical lobe cephalopods: brain structure ideal for exploring the mechanisms forms learning memory.in: J.H. Byrne Oxford Handbook Invertebrate Neurobiology. University Press, 2019: 559-574Google Scholar,2Fiorito G. von Planta C. Scotto P. Problem solving ability Octopus vulgaris Lamarck (Mollusca, Cephalopoda).Behav. Neural. Biol. 1990; 53: 217-230Crossref PubMed Google Scholar,3Richter J.N. Kuba M.J. Pull or push? Octopuses solve puzzle problem.PLoS One. 2016; 11: e0152048Crossref Scopus (30) Scholar,4Reiter S. Hülsdunk Woo Lauterbach M.A. Eberle J.S. Akay L.A. Longo Meier-Credo J. Kretschmer F. Langer J.D. et al.Elucidating control development skin patterning in cuttlefish.Nature. 2018; 562: 361-366Crossref (49) Scholar,5Schnell A.K. Clayton N.S. Cephalopod cognition.Curr. 2019; 29: R726-R732Abstract Full Text PDF (22) Scholar,6Imperadore Fiorito tissue regeneration: consolidating over century knowledge.Front. Physiol. 9: 593Crossref (28) Scholar,7Amodio Boeckle M. Schnell Ostojíc L. Grow smart die young: why did evolve intelligence.Trends Ecol. Evol. 34: 45-56Abstract (0) Scholar,8Hanlon R.T. Messenger J.B. Behaviour. Cambridge 2018Crossref Scholar,9Osorio D. Ménager Tyler C.W. Darmaillacq A.S. Multi-level adaptive camouflage by European cuttlefish.Curr. 2022; 32: 2556-2562.e2Abstract (3) Scholar,10How Norman M.D. Finn Chung W.S. Marshall N.J. Dynamic patterns cephalopods.Front. 2017; 8: 393Crossref (26) Scholar dwarf cuttlefish, Sepia bandensis, is promising model cephalopod species due to its small size, substantial egg production, short generation time, behaviors.11Montague T.G. Rieth I.J. Axel R. Embryonic camouflaging bandensis.Dev. Dyn. 2021; 250: 1688-1703Crossref Cuttlefish dynamically their surroundings changing color, pattern, texture skin. Camouflage optically driven achieved expanding contracting hundreds thousands pigment-filled saccules (chromatophores) skin, which controlled motor neurons emanating from brain. We generated cuttlefish atlas using magnetic resonance imaging (MRI), deep histology, we built interactive web tool (https://www.cuttlebase.org/) host data. Guided observations other cephalopods,12Young J.Z. Anatomy Nervous System Vulgaris. 1971Google Scholar,13Young central nervous system Loligo. I. optic lobe.Philos. Trans. Soc. Lond. B Sci. 1974; 267: 263-302Crossref (114) Scholar,14Young II. Suboesophageal centres.Philos. 1976; 274: 101-167Crossref Scholar,15Young Loligo, III. Higher centres: basal supraoesophageal lobes.Philos. 1977; 276: 351-398Crossref Scholar,16Young V. complex.Philos. 1979; 285: 311-354Crossref Scholar,17Messenger Loligo IV. peduncle olfactory 275-309Crossref Scholar,18Boycott B.B. functional organization officinalis.Proc. Royal 1961; 153: 503-534Crossref Scholar,19Chung Kurniawan N.D. Toward MRI-based mesoscale connectome squid brain.iScience. 2020; 23: 100816Abstract (18) Scholar,20Young lobes vulgaris.Philos. 1962; 245: 19-58Crossref identified 32 lobes, two (75% total volume brain), chromatophore whose directly innervate chromatophores color-changing has been implicated memory. largely conforms anatomy observed provides valuable neural basis behavior experimentally facile cuttlefish.

Language: Английский

Citations

12
The neural basis of visual processing and behavior in cephalopods DOI Creative Commons
Judit R. Pungor, Cristopher M. Niell

Current Biology, Journal Year: 2023, Volume and Issue: 33(20), P. R1106 - R1118

Published: Oct. 1, 2023

Coleoid cephalopods (octopuses, squids and cuttlefishes) are the only branch of animal kingdom outside vertebrates to have evolved both a large brain camera-type eyes. They highly dependent on vision, with majority their devoted visual processing. Their excellent vision supports range advanced visually guided behaviors, from navigation prey capture, ability camouflage based surroundings. However, organization is radically different that vertebrates, as well other invertebrates, providing unique opportunity explore how novel neural architecture for organized functions. Relatively few studies examined cephalopod system using current neuroscience approaches, extent there has not even been measurement single-cell receptive fields in central system. Therefore, remains tremendous amount unknown about basis these extraordinary animals. Here, we review existing knowledge function provide framework examining circuits computational mechanisms mediating remarkable capabilities.

Language: Английский

Citations

7
A perspective on neuroethology: what the past teaches us about the future of neuroethology DOI Creative Commons
M. Jerome Beetz

Journal of Comparative Physiology A, Journal Year: 2024, Volume and Issue: 210(2), P. 325 - 346

Published: Feb. 27, 2024

Abstract For 100 years, the Journal of Comparative Physiology-A has significantly supported research in field neuroethology. The celebration journal’s centennial is a great time point to appreciate recent progress neuroethology and discuss possible avenues field. Animal behavior main source inspiration for neuroethologists. This illustrated by huge diversity investigated behaviors species. To explain at mechanistic level, neuroethologists combine neuroscientific approaches with sophisticated behavioral analysis. rapid technological neuroscience makes highly dynamic exciting research. summarize scientific neuroethology, I went through all abstracts last six International Congresses Neuroethology (ICNs 2010–2022) categorized them based on sensory modalities, experimental model species, topics. highlights gives us perspective field’s future. At end, highlight three topics that may, among others, influence future hope sharing my roots may inspire other scientists follow neuroethological approaches.

Language: Английский

Citations

2
Neural control of cephalopod camouflage DOI Creative Commons
Tessa G. Montague

Current Biology, Journal Year: 2023, Volume and Issue: 33(20), P. R1095 - R1100

Published: Oct. 1, 2023

Language: Английский

Citations

4
High-level RNA editing diversifies the coleoid cephalopod brain proteome DOI
Gjendine Voss, Joshua J. C. Rosenthal

Briefings in Functional Genomics, Journal Year: 2023, Volume and Issue: 22(6), P. 525 - 532

Published: Aug. 9, 2023

Abstract Coleoid cephalopods (octopus, squid and cuttlefish) have unusually complex nervous systems. The coleoid system is also the only one currently known to recode majority of expressed proteins through A-to-I RNA editing. deamination adenosine by deaminase acting on (ADAR) enzymes produces inosine, which interpreted as guanosine during translation. If this occurs in an open reading frame, case for tens thousands editing sites coleoids, it can encoded protein. Here, we describe recent findings aimed at deciphering mechanisms underlying high-level recoding its adaptive potential. We complement ADAR cephalopods, including a recently discovered novel domain sqADAR1. further summarize current evidence supporting role review studies showing that large proportion temperature-sensitive. Despite these new findings, governing high level remain poorly understood. Recent advances using genome may provide useful tools study animals.

Language: Английский

Citations

2