A survey of brain functional network extraction methods using fMRI data

Trends in Neurosciences, Journal Year: 2024, Volume and Issue: 47(8), P. 608 - 621

Published: June 20, 2024

Language: Английский

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Stimulus Selection Influences Prediction of Individual Phenotypes in Naturalistic Conditions

Human Brain Mapping, Journal Year: 2025, Volume and Issue: 46(3)

Published: Feb. 15, 2025

While the use of naturalistic stimuli such as movie clips for understanding individual differences and brain-behaviour relationships attracts increasing interest, influence stimulus selection remains largely unclear. By using machine learning to predict traits (phenotypes) from brain activity evoked during various clips, we show that different can result in distinct prediction performances. In regions related lower-level processing stimulus, a certain degree benefits stronger synchronisation across subjects. contrast, better predictions frontoparietal are mainly associated with larger inter-subject variability. Furthermore, demonstrate while rich social content general achieve predictions, importance specific features highly depends on phenotype under investigation. Overall, our findings underscore careful provide novel insights into conditions, opening new avenues future research.

Language: Английский

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Functional brain network dynamics mediate the relationship between female reproductive aging and interpersonal adversity

Nature Mental Health, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Abstract Premature reproductive aging is linked to heightened stress sensitivity and psychological maladjustment across the life course. However, brain dynamics underlying this relationship are poorly understood. Here, address issue, we analyzed multimodal data from female participants in Adolescent Brain Cognitive Development (longitudinal, N = 441; aged 9–12 years) Human Connectome-Aging (cross-sectional, 130; 36–60 studies. Age-specific intrinsic functional network mediated link between perceptions of greater interpersonal adversity. The adolescent profile overlapped areas glutamatergic dopaminergic receptor density, middle-aged was concentrated visual, attentional default mode networks. two profiles showed opposite relationships with patterns neural variability cortical atrophy observed psychosis versus major depressive disorder. Our findings underscore divergent maturation senescence, which may explain developmentally specific vulnerabilities distinct disorders.

Language: Английский

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The Adolescent Functional Connectome is Dynamically Controlled by a Sparse Core of Cognitive and Topological Hubs

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: March 15, 2025

Abstract Fundamental mechanisms that control the brain’s ability to dynamically respond cognitive demands are poorly understood, especially during periods of accelerated neural and maturation, such as adolescence. Using a sparsity-promoting feedback framework we investigated controllability adolescence functional connectome. Critical costs associated with region’s action on itself rest brain were estimated using resting-state fMRI data from an early longitudinal sample in Adolescent Brain Cognitive Development (ABCD) study (n = 1394; median (IQR) age 10.1 (1.1) years at baseline 12.1 follow-up). A highly reproducible, core set predominantly connected regions retained their over connectome under high costs. They included posterior visual areas, retrosplenial cortex, cuneus precuneus, superior parietal lobule, temporal ventral cortex dorsolateral lateral prefrontal cortices, i.e., both developed developing regions. These central topological organization connectome, consistently engaged spontaneous coordination networks, overlapped hubs play ubiquitous roles function Also, most received (integrated) distributed approximately equal amounts information. regions’ was developmentally stable, critical did not change significantly puberty, suggesting that, despite ongoing maturation changes adolescent brain, fundamental system may be well facilitate information processing response demands.

Language: Английский

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Editorial: Shared responses and individual differences in the human brain during naturalistic stimulations

Frontiers in Human Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: May 5, 2023

EDITORIAL article Front. Hum. Neurosci., 05 May 2023Sec. Brain Imaging and Stimulation Volume 17 - 2023 | https://doi.org/10.3389/fnhum.2023.1201728

Language: Английский

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