bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 17, 2024
Abstract
Objective
Environmental
factors
have
long
been
shown
to
influence
brain
structure
and
adolescent
psychopathology.
However,
almost
no
research
has
included
environmental
spanning
micro-to-macro-systems,
structure,
psychopathology
in
an
integrated
framework.
Here,
we
assessed
the
ways
degree
which
multi-system
during
late
childhood
predict
subcortical
volume
early
adolescence.
Method
We
used
baseline
2-year
follow-up
data
from
Adolescent
Brain
Cognitive
Development
SM
Study
(
N
=
2,766).
A
Bayesian
latent
profile
analysis
was
applied
obtain
distinct
profiles
childhood.
The
were
a
path
their
direct
indirect
effects
on
Results
revealed
nine
profiles.
Two
predicted
greater
externalizing
problems
adolescents:
(i)
adversity
across,
family,
school,
neighborhood
systems
(ii)
family
conflict
low
school
involvement.
In
contrast,
of
affluence
fewer
difficulties.
Further,
higher
volume,
turn,
problems;
whereas,
economic
lower
Conclusion
captured
influences
across
multiple
Specifying
equifinal
pathways
serves
provide
evidence
base
for
establishing
different
types
interventions
based
needs
risk
youth.
Diversity
Inclusion
Statement
current
study
is
part
ongoing
(ABCD
Study®)
youth
are
recruited
elementary
schools
United
States
that
informed
by
gender,
race,
ethnicity,
socioeconomic
status,
urbanicity.
ABCD
Study®
aims
recruit
longitudinally
sampling
sociodemographic
makeup
US
population.
authors
self-identifies
as
member
one
or
more
historically
underrepresented
racial
and/or
ethnic
groups
science.
One
identifies
gender
group
also
representative
communities
collected
contributed
design,
analysis,
interpretation
work.
Finally,
every
effort
made
cite
work
minoritized
academic
research.
Journal of the American Heart Association,
Journal Year:
2024,
Volume and Issue:
13(22)
Published: Nov. 11, 2024
Pediatric
hypertension
is
linked
to
environmental
factors
like
neighborhood
noise
disrupting
sleep,
which
crucial
for
health.
The
specific
interaction
between
and
sleep
health
in
causing
still
needs
be
explored.
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: July 31, 2024
Racism
is
embedded
in
the
fabric
of
society
at
structural,
disciplinary,
hegemonic,
and
interpersonal
levels,
working
as
a
mechanism
that
drives
health
disparities.
In
particular,
stigmatized
views
substance
use
get
entangled
with
racialization,
serving
tool
to
uphold
oppressive
systems.
While
national
institutions
have
made
commitments
dismantle
these
systems
United
States,
anti-racism
has
not
been
integrated
into
biomedical
research
practice.
The
ways
which
researchers
interpret
race
data-without
engaging
structural
racism
inequity-can
only
be
described
inadequate.
Drawing
upon
concepts
from
Public
Health
Critical
Race
praxis,
QuantCrit,
an
framework,
we
recommend
set
guidelines
help
conceptualize
engage
more
responsibly
research.
Purpose:
The
Adolescent
Brain
Cognitive
DevelopmentSM
(ABCD)
Study
is
the
largest
longitudinal
study
on
brain
development
and
adolescent
health
in
United
States.
includes
a
sociodemographically
diverse
cohort
of
nearly
12,000
youth
born
2005-2009,
with
an
open
science
model
making
data
rapidly
available
to
scientific
community.
ABCD
Study®
has
been
used
over
1,100
peer-reviewed
publications
since
its
first
release
2018.
dataset
contains
broad
scope
comprehensive
set
measures
youths’
behavioral,
health,
outcomes,
as
well
extensive
contextual
environmental
that
map
onto
social
determinants
(SDOH).
Understanding
impact
SDOH
developmental
trajectories
youthwill
help
address
early
lifecourse
inequities
lead
disparities
later
life.
However,
use
highlight
need
for
guidance
appropriate,
responsible,
equitable
data.Design
Methods:
Our
conceptual
framework
integrates
National
Institute
Minority
Health
Disparities
Research
Framework
strength-based
equity
perspectives.
We
this
articulate
best
practices
methods
investigations
aim
identify
multilevel
pathways
by
which
structural
systemic
trajectories.Results:
Using
our
model,
we
provide
recommendations
research
using
data.
fifty
can
encompass
across
five
levels
influence:
individual,
interpersonal,
school,
community,
societal.
expand
societal
level
acknowledge
discrimination
root
cause
resulting
among
marginalized
youth.
apply
methodological
example
analysis
approach
perspectives
elucidate
may
influence
cognitive
decision
conclude
strengthening
utility
now
future.Conclusion:
Adolescence
critical
period
subsequent
ramifications
outcomes
lifespan.
Thus,
understanding
inform
prevention
interventions
before
emergence
adulthood.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 17, 2024
Abstract
Objective
Environmental
factors
have
long
been
shown
to
influence
brain
structure
and
adolescent
psychopathology.
However,
almost
no
research
has
included
environmental
spanning
micro-to-macro-systems,
structure,
psychopathology
in
an
integrated
framework.
Here,
we
assessed
the
ways
degree
which
multi-system
during
late
childhood
predict
subcortical
volume
early
adolescence.
Method
We
used
baseline
2-year
follow-up
data
from
Adolescent
Brain
Cognitive
Development
SM
Study
(
N
=
2,766).
A
Bayesian
latent
profile
analysis
was
applied
obtain
distinct
profiles
childhood.
The
were
a
path
their
direct
indirect
effects
on
Results
revealed
nine
profiles.
Two
predicted
greater
externalizing
problems
adolescents:
(i)
adversity
across,
family,
school,
neighborhood
systems
(ii)
family
conflict
low
school
involvement.
In
contrast,
of
affluence
fewer
difficulties.
Further,
higher
volume,
turn,
problems;
whereas,
economic
lower
Conclusion
captured
influences
across
multiple
Specifying
equifinal
pathways
serves
provide
evidence
base
for
establishing
different
types
interventions
based
needs
risk
youth.
Diversity
Inclusion
Statement
current
study
is
part
ongoing
(ABCD
Study®)
youth
are
recruited
elementary
schools
United
States
that
informed
by
gender,
race,
ethnicity,
socioeconomic
status,
urbanicity.
ABCD
Study®
aims
recruit
longitudinally
sampling
sociodemographic
makeup
US
population.
authors
self-identifies
as
member
one
or
more
historically
underrepresented
racial
and/or
ethnic
groups
science.
One
identifies
gender
group
also
representative
communities
collected
contributed
design,
analysis,
interpretation
work.
Finally,
every
effort
made
cite
work
minoritized
academic
research.