The ABCD and HBCD Studies: Longitudinal Studies to Inform Prevention Science DOI
Gayathri J. Dowling, Eric A. Hoffman, Katherine M. Cole

et al.

FOCUS The Journal of Lifelong Learning in Psychiatry, Journal Year: 2024, Volume and Issue: 22(4), P. 449 - 457

Published: Oct. 1, 2024

Increasing rates of overdose among U.S. adolescents and young adults, along with rising emotional distress in these groups, are renewing the urgency for developmentally targeted personalized substance use other mental health prevention interventions. Most programs recognize unique vulnerability childhood adolescence target parents youths, addressing modifiable environmental risk protective factors that affect behavior during periods when brain is most susceptible to change. Until recently, a scarcity comprehensive studies has limited full understanding complexity may neurodevelopment, including exposure pregnancy and/or subsequent adolescence, alongside their dynamic interactions genetics. Two large longitudinal cohort funded by National Institutes Health-the Adolescent Brain Cognitive Development (ABCD) Study HEALthy Child (HBCD) Study-are collecting data on neurodevelopment wide range biological across first two decades life build databases will allow researchers study how individual neurodevelopmental trajectories influenced drugs, adverse experiences, genetics, factors. These already deepening resilience could identify critical windows where interventions can have impact an individual's trajectory. This article describes what being learned from ABCD expected HBCD might inform as children grow more gathered.

Language: Английский

Remote Data Collection of Infant Activity and Sleep Patterns via Wearable Sensors in the HEALthy Brain and Child Development Study (HBCD) DOI Creative Commons
Nicolò Pini, William P. Fifer, Jinseok Oh

et al.

Developmental Cognitive Neuroscience, Journal Year: 2024, Volume and Issue: 69, P. 101446 - 101446

Published: Sept. 13, 2024

Language: Английский

Citations

3
Assessing prenatal and early childhood social and environmental determinants of health in the HEALthy Brain and Child Development Study (HBCD) DOI Creative Commons
Leigh‐Anne Cioffredi, Lea G. Yerby, Heather H. Burris

et al.

Developmental Cognitive Neuroscience, Journal Year: 2024, Volume and Issue: 69, P. 101429 - 101429

Published: Aug. 23, 2024

Language: Английский

Citations

2
Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents DOI Creative Commons
Elysia Poggi Davis,

Bianca T. Leonard,

Robert J. Jirsaraie

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 23, 2024

Abstract Background Unpredictable childhood experiences are an understudied form of early life adversity that impacts neurodevelopment in a sex-specific manner. The neurobiological processes by which exposure to early-life unpredictability development and vulnerability psychopathology remain poorly understood. present study investigates the consequences on limbic network, focusing hippocampus amygdala. Methods Participants included 150 youth (54% female). Early was assessed using Questionnaire Unpredictability Childhood (QUIC). engaged task-fMRI scan between ages 8 17 (223 total observations) measuring BOLD responses novel familiar scenes. Results Exposure associated with contrast (novel vs. familiar) For males, but not females, higher QUIC scores were lower activation response stimuli hippocampal head Secondary psychophysiological interaction (PPI) analyses revealed complementary associations condition-specific functional connectivity right left amygdala, as well amygdala bilaterally. Conclusion has persistent implications for operations circuits. Importantly, consistent emerging experimental animal human studies, differ males females. Further, independent other risk factors including household income negative events, indicating distinct over above more commonly studied types adversity.

Language: Английский

Citations

1
Applying Cognitive Neuroscience to Juvenile Justice: The Role of Brain Development in Decision-Making DOI
Lara Gülten Şentürk

Next frontier., Journal Year: 2024, Volume and Issue: 8(1), P. 105 - 105

Published: Nov. 11, 2024

The intersection of cognitive neuroscience and juvenile justice offers profound insights into understanding the role brain development in decision-making among adolescents. This research explores implications neurodevelopmental processes, particularly prefrontal cortex limbic system, which govern impulse control, risk assessment, emotional regulation. Adolescents are at a stage heightened neuroplasticity, significantly influences their responses. study examines how these developmental factors impact susceptibility to external influences, such as peer pressure. By integrating neuroscientific findings with legal frameworks, highlights importance adopting rehabilitative over punitive approaches systems. underscore need for tailored interventions policies that account neurobiological underpinnings adolescent behavior, fostering balance between accountability opportunity growth rehabilitation.

Language: Английский

Citations

0
The ABCD and HBCD Studies: Longitudinal Studies to Inform Prevention Science DOI
Gayathri J. Dowling, Eric A. Hoffman, Katherine M. Cole

et al.

FOCUS The Journal of Lifelong Learning in Psychiatry, Journal Year: 2024, Volume and Issue: 22(4), P. 449 - 457

Published: Oct. 1, 2024

Increasing rates of overdose among U.S. adolescents and young adults, along with rising emotional distress in these groups, are renewing the urgency for developmentally targeted personalized substance use other mental health prevention interventions. Most programs recognize unique vulnerability childhood adolescence target parents youths, addressing modifiable environmental risk protective factors that affect behavior during periods when brain is most susceptible to change. Until recently, a scarcity comprehensive studies has limited full understanding complexity may neurodevelopment, including exposure pregnancy and/or subsequent adolescence, alongside their dynamic interactions genetics. Two large longitudinal cohort funded by National Institutes Health-the Adolescent Brain Cognitive Development (ABCD) Study HEALthy Child (HBCD) Study-are collecting data on neurodevelopment wide range biological across first two decades life build databases will allow researchers study how individual neurodevelopmental trajectories influenced drugs, adverse experiences, genetics, factors. These already deepening resilience could identify critical windows where interventions can have impact an individual's trajectory. This article describes what being learned from ABCD expected HBCD might inform as children grow more gathered.

Language: Английский

Citations

0