The generalizability of cortical area parcellations across early childhood DOI
Jiaxin Cindy Tu, Michael J. Myers, Wei Li

et al.

Cerebral Cortex, Journal Year: 2025, Volume and Issue: 35(5)

Published: May 1, 2025

Abstract The cerebral cortex consists of distinct areas that develop through intrinsic embryonic patterning and postnatal experiences. Accurate parcellation these in neuroimaging studies improves statistical power cross-study comparability. Given significant brain changes volume, microstructure, connectivity during early life, we hypothesized cortical 1- to 3-year-olds would differ markedly from neonates increasingly resemble adult patterns as development progresses. Here, parcellated the into putative using local functional (FC) gradients 92 toddlers at 2 years old. We demonstrate high reproducibility across two independent datasets. area boundaries were more similar those adults than neonates. While age-specific group better fits underlying FC individuals first 3 years, parcellations still have utility developmental studies, especially children older 6 years. Additionally, provide connectivity-based community assignments parcels, showing fragmented anterior posterior components based on strongest connectivity, yet alignment with systems when weaker was included.

Language: Английский

Highlights of the 2023 Fetal, Infant, and Toddler Neuroimaging Group Annual Meeting DOI Creative Commons
Chad M. Sylvester, Marta Korom,

M. Catalina Camacho

et al.

Developmental Cognitive Neuroscience, Journal Year: 2025, Volume and Issue: unknown, P. 101573 - 101573

Published: May 1, 2025

Language: Английский

Citations

0
The generalizability of cortical area parcellations across early childhood DOI
Jiaxin Cindy Tu, Michael J. Myers, Wei Li

et al.

Cerebral Cortex, Journal Year: 2025, Volume and Issue: 35(5)

Published: May 1, 2025

Abstract The cerebral cortex consists of distinct areas that develop through intrinsic embryonic patterning and postnatal experiences. Accurate parcellation these in neuroimaging studies improves statistical power cross-study comparability. Given significant brain changes volume, microstructure, connectivity during early life, we hypothesized cortical 1- to 3-year-olds would differ markedly from neonates increasingly resemble adult patterns as development progresses. Here, parcellated the into putative using local functional (FC) gradients 92 toddlers at 2 years old. We demonstrate high reproducibility across two independent datasets. area boundaries were more similar those adults than neonates. While age-specific group better fits underlying FC individuals first 3 years, parcellations still have utility developmental studies, especially children older 6 years. Additionally, provide connectivity-based community assignments parcels, showing fragmented anterior posterior components based on strongest connectivity, yet alignment with systems when weaker was included.

Language: Английский

Citations

0