Body roundness index trajectories in Chinese bariatric surgery patients: a retrospective longitudinal study DOI Creative Commons
Kang Zhao, Wenbing Shi, Xinyi Xu

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: May 6, 2025

To investigate the body roundness index (BRI) trajectory categories 12 months post-bariatric surgery and to explore association between BRI metabolic abnormalities. Subject data were pooled from a tertiary hospital at baseline, 3 post-surgery. Anthropometric measurements included mass (BMI). Metabolic biomarkers comprised triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density (LDL-C), glucose (GLU), uric acid (UA). The level was categorized using growth mixture model, multilevel logistic regression model employed relationship risk. A total of 669 patients in this study, comprising 286 males (42.8%) 383 females (57.2%), with an average age 31.70 ± 9.53 years (range 18 65 years). Patients classified into three categories. Compared Low-gradual decline group, High-rapid group had increased risk abnormal HDL-C (OR = 2.84 [95% CI, 1.73 ~ 4.67]), highest proportion sleeve gastrectomy plus jejunojejunal bypass (SG + JJB) single anastomosis duodeno-ileal (SADI-S) (P < 0.001); while High-gradual TG 3.28 [95%CI,1.67-6.42]), 4.30 [95%CI, 2.31 8.00]), LDL-C 2.10 1.12 3.93]), UA 2.33 1.33 4.10]). After adjusting for demographics, lifestyle factors, surgical procedures, distribution outcomes remained primarily consistent. Sleeve (SG) procedures could potentially be associated improvements abdominal obesity status high BRI. trajectories based on may offer insights levels Chinese bariatric patients, but further research is needed confirm these findings.

Language: Английский

Associations of body roundness index with cardiovascular disease and mortality among patients with metabolic syndrome DOI
Ziqi Chen, Iokfai Cheang, Xu Zhu

et al.

Diabetes Obesity and Metabolism, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract Aims The prevalence of metabolic syndrome (MetS) is increasing due to ageing populations and lifestyle changes, making it crucial understand the relationship between body fat distribution cardiovascular outcomes. Traditional measures such as mass index (BMI) have limitations in assessing abdominal obesity. roundness (BRI), a novel anthropometric measure combining waist circumference height, has shown promise evaluating this risk. This study aims explore association BRI disease (CVD) mortality nationally representative sample US adults with MetS. Materials Methods retrospective used data from National Health Nutrition Examination Surveys (NHANES) 2001–2016, including 10 527 MetS‐diagnosed participants. was calculated cohort divided into quartiles. Logistic regression Cox proportional hazards models assessed CVD prevalence, all‐cause cardiovascular‐specific mortality. Kaplan–Meier curves restricted cubic spline analyses visualized survival patterns non‐linear relationships, sensitivity analysis for validation. Results Higher quartiles were significantly associated increased (odds ratio [OR]: 1.56 [1.32–1.84], p < 0.001). In fully adjusted model, demonstrated U‐shaped mortality, threshold value 6.89 ( ≤0.001). Above threshold, each additional unit linked 9% increase risk (hazard [HR]: 1.09 [1.02–1.15], = 0.006) an 8% rise overall (HR: 1.08 [1.04–1.12], Conversely, BMI showed paradoxical reduced unadjusted models, which became insignificant after adjusting confounders 0.195; 0.144). Conclusions might be more reliable predictor outcomes MetS patients than BMI. identified can assist clinicians accurate prognostic evaluations. However, findings may vary by age gender, underscoring need further research diverse populations.

Language: Английский

Citations

0
Association between abdominal obesity and cognitive decline among Chinese middle-aged and older adults: a 10-year follow-up from CHARLS DOI Creative Commons
Qiong Wu, Zhu Xu, Dan Feng

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: April 15, 2025

Introduction The relationship between abdominal obesity and cognitive decline has controversial results, the mediating effect of high-density lipoprotein cholesterol (HDL-C) them remains uncertain. This study aims to explore association in middle-aged older adults, including dose-response age differences, as well HDL-C. Methods Data were obtained from China Health Retirement Longitudinal Study (CHARLS), involving 3,807 participants aged 45 above 2010 2020. TICS-10 was used assess function, group-based trajectory model (GBTM) potential heterogeneity changes. Abdominal measured by baseline waist circumference (WC) a sequentially adjusted unordered multinomial logistic regression investigate adults. Restricted cubic spline (RCS) adopted analyze WC risk decline. HDL-C mediator examine causal chain Results Among participants, total 1,631 individuals (42.84%) had obesity. GBTM identified 3 function trajectories: rapid (11.0%), slow (41.1%) stable groups (47.9%). After controlling for confounders, with less likely experience ( OR : 0.67, 95% CI 0.51–0.8) 0.81, 0.69–0.95) compared those normal WC. RCS analysis showed decreased increasing In subgroup analysis, protective significant only population 50 above. mediated 19.15% P &lt; 0.05) Conclusion on Chinese playing role

Language: Английский

Citations

0
Joint association of triglyceride glucose index (TyG) and body roundness index (BRI) with stroke incidence: a national cohort study DOI Creative Commons

Bingxue Wang,

Liying Li, Nelson L.S. Tang

et al.

Cardiovascular Diabetology, Journal Year: 2025, Volume and Issue: 24(1)

Published: April 16, 2025

Abstract Background Insulin resistance (IR), as quantified by the triglyceride glucose (TyG) index, and visceral obesity, assessed body roundness index (BRI), have been identified pivotal risk factors for stroke. However, combined impact of these two indicators on stroke has not thoroughly investigated. This study aims to investigate both separate associations, well potential interactions, between TyG and/or BRI with respect incidence. Methods cohort encompassed 6621 respondents who were free at baseline from China Health Retirement Longitudinal Study (CHARLS). Participants categorized based median values or/and BRI. Cox proportional hazards regression models employed examine associations alone, their effects Both additive multiplicative interaction further estimated. Results Among participants aged 45 years or older, mean (SD) age was 58.06 (8.57) years, 2951 (44.6%) being male. During a follow-up period up 9 743 individuals experienced events. Compared low BRI, adjusted hazard ratios (HRs) follows: 1.36 (95% confidence interval [CI] 1.05–1.75) high 1.61 CI 1.27–2.05) 1.78 1.40–2.26) Neither nor interactions incident statistically significant. The combination enhanced predictive capability compared either biomarker alone. Conclusion We discovered that are strongly associated joint assessment enhances stroke, underscoring critical role IR adiposity in identification screening risk. Graphical abstract

Language: Английский

Citations

0
The Relationship between Visceral Fat Accumulation and Risk of Cardiometabolic Multimorbidity: The Roles of Accelerated Biological Aging DOI Open Access
Tianyu Zhu, Yixing Tian,

Jinqi Wang

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1397 - 1397

Published: April 21, 2025

Objectives: To investigate the association between visceral fat accumulation and risk of cardiometabolic multimorbidity (CMM) potential roles accelerated biological aging in this relationship. Methods: Using data from UK Biobank, a nationwide cohort study was conducted using available baseline body roundness index (BRI) measurement. Biological assessed Klemera–Doubal method for age phenotypic algorithms. The BRI CMM estimated Cox proportional hazards regression model, while were examined through interaction mediation analyses. Results: During median follow-up 14.52 years, 6156 cases identified. A significant observed CMM. hazard ratio (HR) 3.72 (95% confidence interval [CI]: 3.35–4.13) individuals highest quartile compared with those lowest BRI. More importantly, (AUC, 0.701; 95% CI, 0.694–0.707) demonstrated superior predictive performance relative to mass 0.657; 0.650–0.664). Furthermore, exhibited additive interactions on CMM, partially mediated Conclusions: These findings provide evidence application as novel readily accessible screening tool associated suggesting that effective management deceleration may hold promise reducing risk.

Language: Английский

Citations

0
Body roundness index trajectories in Chinese bariatric surgery patients: a retrospective longitudinal study DOI Creative Commons
Kang Zhao, Wenbing Shi, Xinyi Xu

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: May 6, 2025

To investigate the body roundness index (BRI) trajectory categories 12 months post-bariatric surgery and to explore association between BRI metabolic abnormalities. Subject data were pooled from a tertiary hospital at baseline, 3 post-surgery. Anthropometric measurements included mass (BMI). Metabolic biomarkers comprised triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density (LDL-C), glucose (GLU), uric acid (UA). The level was categorized using growth mixture model, multilevel logistic regression model employed relationship risk. A total of 669 patients in this study, comprising 286 males (42.8%) 383 females (57.2%), with an average age 31.70 ± 9.53 years (range 18 65 years). Patients classified into three categories. Compared Low-gradual decline group, High-rapid group had increased risk abnormal HDL-C (OR = 2.84 [95% CI, 1.73 ~ 4.67]), highest proportion sleeve gastrectomy plus jejunojejunal bypass (SG + JJB) single anastomosis duodeno-ileal (SADI-S) (P < 0.001); while High-gradual TG 3.28 [95%CI,1.67-6.42]), 4.30 [95%CI, 2.31 8.00]), LDL-C 2.10 1.12 3.93]), UA 2.33 1.33 4.10]). After adjusting for demographics, lifestyle factors, surgical procedures, distribution outcomes remained primarily consistent. Sleeve (SG) procedures could potentially be associated improvements abdominal obesity status high BRI. trajectories based on may offer insights levels Chinese bariatric patients, but further research is needed confirm these findings.

Language: Английский

Citations

0