What are biopharmaceuticals?

Published: Jan. 10, 2025

Throughout history, biopharmaceuticals have been essential in addressing health crises and enhancing human well-being. With advancements genetic engineering, biotechnology, bioinformatics, the development approval rates of new surged, placing them at forefront pharmaceutical field. Modern manufacturing processes streamlined regulatory pathways further expedited timelines, providing hope for previously untreatable conditions significantly improving patients’ quality life worldwide. However, despite these advancements, ambiguity persists regarding definition due to use varied terms a lack standardized definitions. This article addresses this confusion by proposing clear comprehensive biopharmaceuticals. Additionally, we present reclassification into seven distinct verticals based on their functions. We assert that not only offer superior therapeutic benefits but also contribute environmental sustainability, promoting healthier planet. Thus, aims clarify scope advocate broader adoption pursuit global integrity.

Language: Английский

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Hepatobiliary Cancers in Saudi Arabia From 2000 to 2025

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Language: Английский

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Marine L-Arginase encapsulated in Poly (lactic-co-glycolic acid) Nanoparticles: A Novel Anti-Tumor Strategy for Effective Hepatocellular carcinoma Treatment In Vitro and In Vivo

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106980 - 106980

Published: April 1, 2025

Language: Английский

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The Role of Metabolic Reprogramming in the Tumor Immune Microenvironment: Mechanisms and Opportunities for Immunotherapy in Hepatocellular Carcinoma

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5584 - 5584

Published: May 21, 2024

As one of the emerging hallmarks tumorigenesis and tumor progression, metabolic remodeling is common in microenvironment. Hepatocellular carcinoma (HCC) third leading cause global tumor-related mortality, causing a series alterations response to nutrient availability consumption fulfill demands biosynthesis carcinogenesis. Despite efficacy immunotherapy treating HCC, rate remains unsatisfactory. Recently, research has focused on reprogramming its effects immune state microenvironment, rate. In this review, we delineate observed HCC influence We discuss strategies aimed at enhancing rates overcoming resistance through interventions, focusing targeting glucose, lipid, or amino acid metabolism, as well systemic regulation.

Language: Английский

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Comprehensive insight into exploring the potential of microbial enzymes in cancer therapy: Progress, challenges, and opportunities: A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134535 - 134535

Published: Aug. 5, 2024

Language: Английский

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Methanolic extracts of litchi (Litchi chinensis Sonn.): A novel approach of targeting glucose-6-phosphate dehydrogenase for liver cancer therapy

Toxicon, Journal Year: 2024, Volume and Issue: 248, P. 108047 - 108047

Published: July 26, 2024

Language: Английский

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A novel nanocomposite fabrication of chitosan with tungstate oxide nanoplatform doped with bovine lactoperoxidase: characterizations and diverse biological assessments

Biomass Conversion and Biorefinery, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 17, 2024

Language: Английский

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A New Fluorescent Probe with Large Stokes Shift for Selective and Sensitive Detection of Arginine

Published: Jan. 1, 2024

Language: Английский

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A New Fluorescent Probe with Large Stokes Shift for Selective and Sensitive Detection of Arginine

Published: Jan. 1, 2024

Language: Английский

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A new fluorescent probe with large Stokes shift for selective and sensitive detection of arginine

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 458, P. 115942 - 115942

Published: Aug. 10, 2024

Language: Английский

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