Cysteine
(Cys),
homocysteine
(Hcy)
and
glutathione
(GSH)
act
as
significant
roles
in
many
physiological
processes,
their
abnormal
proliferation
will
cause
multiple
diseases
including
Alzheimer's
disease,
Parkinson's
Cardiovascular
atherosclerosis,
soft
tissue
damage.
However,
It
is
challenging
work
to
develop
a
efficient
method
for
differentiating
detecting
GSH,
Cys
Hcy
because
of
similarity
structures
functions.
In
this
work,
smart
fluorescent
probe
FBCN
based
on
curcumin
was
rationally
devised
developed
by
etherifying
the
phenol
hydroxyl
group
FBC
with
NBD-Cl,
which
emitted
strong
green
at
516
nm.
distinguished
from
Cys/GSH
naked
eyes
color
variation
solution
sunlight.
Meanwhile,
GSH
induced
powerful
fluorescence
quenching
solution,
but
transformed
luminous
yellow
accompanied
emission
wavelength
redshifted
nm
540
or
553
existence
Cys,
respectively.
Probe
had
outstanding
sensitivity
anti-interference,
low
detection
limit
(61.6
nM,
77.7
0.29
µM
corresponded
Hcy,
respectively),
short
response
time
(the
1
min,
2
min
5
respectively).
The
DFT
calculation
HRMS
verified
sensing
mechanism
biothiols.
addition,
successfully
utilized
detect
three
biothiols
levels
living
cell
zebrafish.
Chemical Science,
Journal Year:
2024,
Volume and Issue:
15(11), P. 3920 - 3927
Published: Jan. 1, 2024
Stimuli-responsive
aggregation-induced
emission
(AIE)
materials
are
highly
sensitive
and
rapidly
responsive
to
external
signals,
making
them
ideal
solid
for
anti-counterfeiting
encryption.
However,
the
limited
conformational
packing
variations
resulting
from
regio-isomerization
with
a
single
substituent
restricts
stimuli-responsive
behavior
of
these
materials.
In
this
work,
several
AIE-active
regio-structural
isomers
based
on
salicylaldehyde
Schiff
base
scaffold
have
been
straightforwardly
obtained
through
multiple
substitutions
bromide
triphenylamine
moieties.
Solvent-effect
experiments
demonstrate
their
different
orders
charge-transfer
excited-state
intramolecular
proton
transfer
upon
photoexcitation,
indicating
regulation
processes
via
multi-site
isomerization.
These
also
mechanochromism
acidichromism,
allowing
adjustable
effects.
As
demonstration,
p-Br-TPA
both
acidichromism
can
be
synergistically
utilized
multi-level
decryption.
This
study
successfully
regulates
evolution
excited
states
isomerization,
offering
general
approach
achieving
tunable
properties
in
bases
toward
Inorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
63(10), P. 4697 - 4706
Published: Feb. 26, 2024
Benefiting
from
the
unique
photoluminescence
behavior
of
lanthanide(III)
ions
and
organic
ligands,
a
metal-organic
framework
(Ln-MOF)
material
can
simultaneously
demonstrate
cations
molecules
endow
its
superior
applications
fluorescence
sensing
behaviors.
Herein,
we
present
europium(III)
MOF
{[Eu
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(6), P. 3479 - 3487
Published: Jan. 1, 2024
A
new
strategy
for
multi-component
synthesis
of
functionalized
carbazole-based
AIEgens
from
lignin
phenolic
β-O-4
model
linkages
was
developed
by
a
one-pot,
two-step
method
with
low-cost
CuCl
2
as
catalyst.
Advanced Science,
Journal Year:
2023,
Volume and Issue:
11(9)
Published: Dec. 15, 2023
Abstract
Artificial
aggregation‐induced
emission
luminogens
(AIEgens)
have
flourished
in
bio‐applications
with
the
development
of
synthetic
chemistry,
which
however
are
plagued
by
issues
like
singularity
structures
and
non‐renewability.
The
unique
renewability
biomass
moieties
can
compensate
for
these
drawbacks,
but
their
properties
hard
to
design
regulate
due
confined
structures.
Therefore,
it
appears
be
a
reasonable
approach
derive
AIEgens
from
abundant
(BioAIEgens),
integrating
bilateral
advantages
both
natural
AIEgens.
In
this
work,
blue‐violet
emissive
coumarin
its
lactone
structure
serving
as
rare
acceptor,
is
utilized
construct
donor‐π‐acceptor
typed
BioAIE
isomers
incorporating
propeller‐like
electron‐donating
triphenylamine
(TPA)
unit.
results
show
that
Cm‐
p
‐TPA
undergoes
charge
transfer
keto
form,
emitting
red
light
at
600
nm,
applied
monitor
Cu
2+
concentration
during
mitophagy
using
fluorescence
lifetime
imaging
microscopy
because
excellent
biocompatibility,
photostability,
specific
recognition
.
This
work
not
only
demonstrates
feasibility
utilizing
positional
isomerization
modulate
excited‐state
evolutions
resultant
optical
properties,
also
provides
evidence
rationality
constructing
biologically‐active
BioAIEgens
via
biomass‐derivatization
concept.
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(1)
Published: Jan. 1, 2025
Abstract
Hydrazine
had
important
applications
in
medicine,
the
chemical
industry,
and
agriculture,
but
hydrazine
pollution
was
also
very
harmful
to
human
beings.
Chemists
have
reported
many
types
of
fluorescent
probes.
However,
it
still
challenging
continuously
improve
selectivity
sensitivity
Here,
we
designed
synthesized
a
novel
NH
2
probe
based
on
neighboring
group
participation
(NGP).
We
choose
bromine
chlorine
as
respectively.
The
good
anti‐interference
ability.
detection
limits
were
0.027
µM
(probe
A)
0.054
B).
sensing
mechanism
confirmed
by
1
H
NMR,
13
C
FT‐IR.
Theoretical
calculation
showed
that
energy
barrier
could
be
reduced
NGP.
In
terms
application,
has
function
quantitative
actual
water
samples.
