Insomnia, Poor Sleep Quality and Sleep Duration, and Risk for COVID-19 Infection and Hospitalization

The American Journal of Medicine, Journal Year: 2023, Volume and Issue: 136(8), P. 780 - 788.e5

Published: April 17, 2023

Language: Английский

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Multidimensional Sleep Health Prior to SARS-CoV-2 Infection and Risk of Post–COVID-19 Condition

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(5), P. e2315885 - e2315885

Published: May 30, 2023

Importance The association of multiple healthy sleep dimensions with post–COVID-19 condition (PCC), also known as long COVID, has not been investigated. Objective To examine whether multidimensional health before and during the COVID-19 pandemic, prior to SARS-CoV-2 infection, was associated risk PCC. Design, Setting, Participants This prospective cohort study (2015-2021) included Nurses’ Health Study II participants who reported testing positive (n = 2303) for infection in a substudy series COVID-19–related surveys 32 249) between April 2020 November 2021. After exclusion incomplete information about nonresponse question PCC, 1979 women were analysis. Exposures Sleep measured both (June 1, 2015, May 31, 2017) early (April 1 August 2020) pandemic. Prepandemic score defined according 5 dimensions: morning chronotype (assessed 2015), 7 8 hours per day, low insomnia symptoms, no snoring, frequent daytime dysfunction (all assessed 2017). On first survey (returned 2020), average daily duration quality past days queried. Main Outcomes Measures PCC (≥4 weeks symptoms) self-reported year follow-up. Comparisons examined June 8, 2022, January 9, 2023, using Poisson regression models. Results Of reporting (mean [SD] age, 64.7 [4.6] years; [100%] female; 1924 [97.2%] White vs 55 [2.8%] other races ethnicities), 845 (42.7%) frontline care workers, 870 (44.0%) developed Compared had prepandemic 0 or (least healthy), those scored (most healthy) 30% lower developing (multivariable-adjusted relative risk, 0.70; 95% CI, 0.52-0.94; P trend <.001). Associations did differ by worker status. No little good pandemic independently (relative 0.83 [95% 0.71-0.98] 0.82 0.69-0.99], respectively). similar when having more symptoms ongoing at time assessment. Conclusions Relevance findings indicate that may be protective against Future research should investigate interventions on prevent improve symptoms.

Language: Английский

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Sleep During the COVID-19 Pandemic

Current Psychiatry Reports, Journal Year: 2022, Volume and Issue: 24(11), P. 635 - 643

Published: Oct. 4, 2022

Language: Английский

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Kognitive Störungen und Schlafstörungen bei Long-COVID

Der Nervenarzt, Journal Year: 2022, Volume and Issue: 93(8), P. 779 - 787

Published: May 16, 2022

Language: Английский

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Sleep disturbance increases the risk of severity and acquisition of COVID-19: a systematic review and meta-analysis

European journal of medical research, Journal Year: 2023, Volume and Issue: 28(1)

Published: Oct. 18, 2023

Abstract Background Understanding the association between sleep quality and COVID-19 outcomes is crucial for effective preventive strategies patient management. This systematic review aims to evaluate impact of as a risk factor acquiring infection severity disease. Methods A comprehensive search electronic databases was conducted identify relevant studies published from inception pandemic which 31 st December 2019 until 30 April 2023. Studies investigating relationship infection, or disease were included. Random effect meta-analysis performed with odds ratios (OR) their 95% confidence intervals (95% CI) measures. Results Out initial 1,132 articles identified, 12 met inclusion criteria. All observational (cohort, case–control, cross-sectional). The examined in 6 studies, results our showed that participants poor 16% increase regarding acquisition (OR 1.16; CI 1.03, 1.32; I 2 = 65.2%, p 0.02). Our 51% incidence primary composite outcome 1.51; 1.25, 1.81; 57.85%, < 0.001). result subgroup analysis also significantly increased mortality (RR 0.67; 0.50, 0.90; 31%, 0.008), 1.47; 1.19, 1.80; 3.21%, 0.001) when comparing group those good quality. Conclusion study highlights significant an well worse clinical outcomes.

Language: Английский

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Sleep quality during and after severe acute respiratory syndrome coronavirus 2 (COVID‐19) lockdowns in the UK: Results from the SleepQuest study

Journal of Sleep Research, Journal Year: 2024, Volume and Issue: 33(6)

Published: April 23, 2024

Summary Sleep is fundamental to health. The aim of this study was analyse and determine factors predicting sleep quality during after national lockdowns due severe acute respiratory syndrome coronavirus 2 (COVID‐19) in the UK. A longitudinal online survey‐based (SleepQuest) involving UK adults administered Spring 2020, Winter 2022 including questionnaires probing quality, depression, anxiety, beliefs about sleep, demographics, COVID‐19 status, exercise. primary outcome (Pittsburgh Quality Index). linear mixed‐effects model evaluated associated with baseline quality. Complete data were provided by 3306 participants 2196 1193 2022. Participants mostly female (73.8%), white (97.4%), aged over 50 years (81.0%). On average, reported poor 2020 (mean [SD] Pittsburgh Index score = 6.59 [3.6]) 6.44 [3.6]), improved but still 6.17 [3.5]). Improved driven better subjective reduced daytime dysfunction latency. Being female, older, having caring responsibilities, working nightshifts, reporting higher levels unhelpful worse PSQI scores. Better more days exercising per week at baseline. Interventions focusing on improving mental health, exercise, attitudes towards particularly at‐risk groups, may improve sleep‐related outcomes future pandemics.

Language: Английский

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Healthy sleep patterns and risk of hospitalization for infection: a large community-based cohort study

Translational Psychiatry, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 27, 2025

Sleep behaviours are potentially modifiable risk factors for infectious disease. However, little is known about the combined effects of multiple sleep on infections. We investigated prospective associations healthy patterns with hospitalization infection in 397,523 participants (mean (SD) age: 56.3 (8.1) years) from UK Biobank. Healthy were defined by scores according to a combination adequate duration (7–8 h/day), early chronotype, no insomnia, and excessive daytime sleepiness. During median follow-up 13.5 (interquartile range: 12.4–14.2) years, 60,377 cases any documented. A score was inversely associated various subtypes dose-dependent manner (P trend < 0.001). The between one-point increment infections ranged 9% lower sepsis (HR = 0.91; 95% CI, 0.89–0.93) 20% liver 0.80; 0.74–0.87). More than 10% hospitalizations could have been prevented if all adhered four low-risk behaviours. Adherence pattern decreased infections, especially individuals <65 years age females interaction 0.00045). Our findings highlight potential behaviour interventions primary prevention diseases.

Language: Английский

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Self-reported short and long sleep duration, sleep debt and insomnia are associated with several types of infections: Results from the Norwegian practice-based research network in general practice – PraksisNett

Sleep Medicine X, Journal Year: 2023, Volume and Issue: 5, P. 100074 - 100074

Published: May 5, 2023

The objective was to assess the association between self-reported infections and sleep duration, debt, chronic insomnia, insomnia severity.

Language: Английский

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The association between self-reported sleep problems, infection, and antibiotic use in patients in general practice

Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14

Published: March 2, 2023

There is emerging evidence that sleep problems and short duration increase the risk of infection. We aimed to assess whether chronic insomnia disorder, problems, circadian preference based on self-report were associated with infections antibiotic use among patients visiting their general practitioner (GP).We conducted a cross-sectional study 1,848 unselected in Norway GP during 2020.The completed one-page questionnaire while waiting for consultation, included validated Bergen Insomnia Scale (BIS), questions self-assessed problem, they have had any or used antibiotics last 3 months. Relative risks (RR) estimated using modified Poisson regression models.The infection was 27% (95% CI RR 1.11-1.46) 44% higher 1.12-1.84) sleeping < 6 h >9 h, respectively, compared those 7-8 h. The also increased disorder problem. For use, problem.Among GP, duration, problem prevalence use. These findings support notion strong association between

Language: Английский

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No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses

European Journal of Clinical Investigation, Journal Year: 2024, Volume and Issue: 54(6)

Published: March 1, 2024

Abstract Background Disturbances in habitual sleep have been associated with multiple age‐associated diseases. However, the biological mechanisms underpinning these associations remain largely unclear. We assessed possible involvement of circulating immune system by determining between traits and white blood cell counts using multivariable‐adjusted linear regression Mendelian randomization. Methods Cross‐sectional analyses were done participants within normal range total (>4.5 × 10 9 <11.0 /μL) from UK Biobank. For traits, we examined (short long) duration, chronotype, insomnia symptoms daytime dozing. Two‐sample randomization instruments for derived European‐ancestry Biobank (over 410,000 participants) SNP‐outcome data Blood Cell Consortium ( N = 563,946) to which no contributed. Results Using 357,656 (mean [standard deviation] age: 56.5 [8.1] years, 44.4% men), did not find evidence that disturbances any studied differences (total, lymphocytes, neutrophiles, eosinophiles basophiles). Also, Randomization. Conclusion Based on results two different methodologies, are unlikely cause changes thereby be underlying observed sleep‐disease associations.

Language: Английский

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