Real-time heart rate variability according to ambulatory glucose profile in patients with diabetes mellitus DOI Creative Commons
Sung Il Im,

Su Hyun Bae,

Soo Jin Kim

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 5, 2023

Abstract Background Autonomic neuropathy commonly occurs as a long-term complication of diabetes mellitus (DM) and can be diagnosed based on heart rate variability (HRV), calculated from electrocardiogram (ECG) recordings. There are limited data HRV using real-time ECG ambulatory glucose monitoring in patients with DM. Methods Results A total 43 (66.3±7.5 years) DM underwent continuous (225.7±107.3 hours) for remote system. We compared the according to profile. Data were analyzed target range (TIR). no significant differences baseline characteristics TIR. During monitoring, we checked levels (a 15,090 times) simultaneously all patients. Both time- frequency-domain HRVs lower when had poorly controlled (>200 mg/dL) TIR<70% normally (<200 TIR>70%. In addition, respiratory rates increased (P<0.001). Conclusions Poorly independently associated This was further substantiated by independent association between measurements hyperglycemia HRV. These strongly suggest that cardiac autonomic dysfunction is caused elevated blood sugar levels.

Language: Английский

Angiotensin II: A novel biomarker in vascular diseases DOI
Qinyi Zhou, Jing Pan, Wang Liu

et al.

Clinica Chimica Acta, Journal Year: 2025, Volume and Issue: 568, P. 120154 - 120154

Published: Jan. 22, 2025

Language: Английский

Citations

1
Real-time heart rate variability according to ambulatory glucose profile in patients with diabetes mellitus DOI Creative Commons
Sung Il Im, Soo Jin Kim,

Su Hyun Bae

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Nov. 16, 2023

Autonomic neuropathy commonly occurs as a long-term complication of diabetes mellitus (DM) and can be diagnosed based on heart rate variability (HRV), calculated from electrocardiogram (ECG) recordings. There are limited data HRV using real-time ECG ambulatory glucose monitoring in patients with DM. The aim this study was to investigate according levels A total 43 (66.3 ± 7.5 years) DM underwent continuous (225.7 107.3 h) for remote system. We compared the profile. Data were analyzed target range (TIR). no significant differences baseline characteristics TIR. During monitoring, we checked (a 15,090 times) simultaneously all patients. Both time- frequency-domain HRVs lower when had poorly controlled (TIR < 70%) well > 70%). In addition, respiratory rates increased (P 0.001). Poorly independently associated This further substantiated by independent association between measurements hyperglycemia HRV. These strongly suggest that cardiac autonomic dysfunction is caused elevated blood sugar levels.

Language: Английский

Citations

5
The Benefits of Oral Glucose-Lowering Agents: GLP-1 Receptor Agonists, DPP-4 and SGLT-2 Inhibitors on Myocardial Ischaemia/Reperfusion Injury DOI

Xudong Huang,

Ding‐Sheng Jiang,

Xin Feng

et al.

European Journal of Pharmacology, Journal Year: 2024, Volume and Issue: 976, P. 176698 - 176698

Published: May 29, 2024

Language: Английский

Citations

1
Environmental exposures and blood pressure in adolescents and adults in the T1D exchange clinic registry DOI
Stephanie Griggs, Grant A. Pignatiello, Issam Motairek

et al.

Journal of Diabetes and its Complications, Journal Year: 2023, Volume and Issue: 37(10), P. 108594 - 108594

Published: Aug. 25, 2023

Language: Английский

Citations

2
The new face of diabetes mellitus — rhythm and conduction disorders DOI Open Access

Mark S. Tyurypov,

Polina O. Odnokol, Г. Г. Кутелев

et al.

Russian Military Medical Academy Reports, Journal Year: 2024, Volume and Issue: 43(2), P. 193 - 201

Published: July 31, 2024

This review article is devoted to changes in heart rhythm against the background of type 2 diabetes mellitus, which one most common endocrine diseases. In recent years, there has been an increasing association between mellitus and disorders. Arrhythmias such as tachycardia, bradycardia atrial fibrillation are patients with can have serious consequences on health quality life. Type DM increasingly worldwide due rise sedentary lifestyles, overweight, abdominal forms obesity, diets containing too much fat carbohydrates. Insulin-independent a metabolic disease responsible for autonomic neuropathy that affects both sympathetic parasympathetic fibers, be explained by adverse effect blood glucose levels rate variability (HRV). Although gold standard cardiovascular reflex tests assess neuropathy, important measurement HRV variation two consecutive contractions: higher variation, activity nervous system. A high reflects fact person constantly adapt microenvironment. Thus, low marker risk.

Language: Английский

Citations

0
Real-time heart rate variability according to ambulatory glucose profile in patients with diabetes mellitus DOI Creative Commons
Sung Il Im,

Su Hyun Bae,

Soo Jin Kim

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 5, 2023

Abstract Background Autonomic neuropathy commonly occurs as a long-term complication of diabetes mellitus (DM) and can be diagnosed based on heart rate variability (HRV), calculated from electrocardiogram (ECG) recordings. There are limited data HRV using real-time ECG ambulatory glucose monitoring in patients with DM. Methods Results A total 43 (66.3±7.5 years) DM underwent continuous (225.7±107.3 hours) for remote system. We compared the according to profile. Data were analyzed target range (TIR). no significant differences baseline characteristics TIR. During monitoring, we checked levels (a 15,090 times) simultaneously all patients. Both time- frequency-domain HRVs lower when had poorly controlled (>200 mg/dL) TIR<70% normally (<200 TIR>70%. In addition, respiratory rates increased (P<0.001). Conclusions Poorly independently associated This was further substantiated by independent association between measurements hyperglycemia HRV. These strongly suggest that cardiac autonomic dysfunction is caused elevated blood sugar levels.

Language: Английский

Citations

0