Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(12)
Published: Nov. 19, 2024
Language: Английский
Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(12)
Published: Nov. 19, 2024
Language: Английский
Egyptian Journal of Basic and Applied Sciences, Journal Year: 2024, Volume and Issue: 11(1), P. 659 - 684
Published: Aug. 31, 2024
Tartrazine (TAZ), a synthetic lemon-yellow azo dye, finds uses in food ingredients, pharmaceuticals, and cosmetics. Treatment with TAZ during pregnancy Wistar rats will be investigated to assess its impact on embryonic development. Eighteen pregnant were divided into three groups: the control group two groups administered via gavage at doses of 7.5 mg/kg 15 from day 5 18. At 19 days gestation, female euthanised their foetuses extracted for assessment. Analysis was conducted evaluate mortality, growth, morphological, skeletal abnormalities. Furthermore, maternal fetal tissues subjected histological analysis oxidative state evaluated. No observed corrected body weight by TAZ. However, it resulted inhibited development, morphological defects, resorption, delayed ossification. Daily administration altered histology placenta, liver, kidney. Malonaldehyde increased antioxidant markers such as glutathione, catalase superoxide dismutase decreased, causing hepatic stress. Our study indicates that is embryotoxic rats. Therefore, should avoided process organogenesis crucial gestational time.
Language: Английский
Citations
0Child and Adolescent Psychiatry and Mental Health, Journal Year: 2024, Volume and Issue: 18(1)
Published: Sept. 11, 2024
Language: Английский
Citations
0Reproductive Toxicology, Journal Year: 2024, Volume and Issue: unknown, P. 108718 - 108718
Published: Sept. 1, 2024
Citations
0Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(12)
Published: Nov. 19, 2024
Language: Английский
Citations
0