Association of sarcopenia, ambient air pollution and cognitive function in a community-dwelling middle-aged and elderly Korean population: a community-based cohort study DOI Creative Commons
Jane Lee, Hae Dong Woo, Ji Hyun Kim

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(12), P. e092448 - e092448

Published: Dec. 1, 2024

Objectives To investigate the association of sarcopenia, exposure to medium-term long-term ambient particulate matter 2.5 µm and 10 (PM PM ) pollution cognitive function in a community-dwelling cohort middle-aged older adults South Korea. Design A community-based prospective study. Setting In Korean Genome Epidemiology Study (KoGES). Participants The participants were drawn from seventh follow-up visit conducted between 2015 2016 KoGES Ansung who had participated an ageing substudy. Outcome measures Cognitive was evaluated by version Mini-Mental State Examination (K-MMSE) decreased defined as K-MMSE score 23 or less. Results Of 2274 (mean age 70.1 years, 58.3% women mean annual levels 30.7 52.2 μg/m 3 , respectively), 8.7% (n=197) sarcopenic, 35.8% (n=814) possible sarcopenic 55.5% (n=1263) non-sarcopenic. predictors sarcopenia included body mass index, function, age, marital status, hypertension physical activity. Exposure for average duration 1 month years not selected predictor sarcopenia. with associated lower scores (β=−1.51, p<0.0001) compared those without (OR 2.34, 95% CI 1.56 3.52). effect modification on generally detected. Conclusions this observational study aged 50 older, function. However, did modify relationship

Language: Английский

Association of residential green space with risk of sarcopenia and the role of air pollution: evidence from UK Biobank DOI
Xiaoyu Zhao,

Jinqi Wang,

Zhiyuan Wu

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 125857 - 125857

Published: Feb. 1, 2025

Language: Английский

Citations

0
Association between indoor ventilation frequency and low muscle mass among older adults in China: a national cross-sectional research DOI Creative Commons
Jun Wei, Yunfeng Lin,

Xiaobing Xian

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 26, 2025

Previous studies have established associations between indoor air pollution and loss of muscle mass. While ventilation improves quality, its association with low mass (LMM) remains unexplored. We investigated the frequency (IVF) LMM in older Chinese adults. Utilizing data from China Longitudinal Healthy Longevity Survey (CLHLS), IVF was assessed via self-reported weekly window-opening each season past year. defined using appendicular skeletal (ASM) prediction equations. Binary logistic regression models were employed to evaluate LMM, subgroup sensitivity analyses conducted. After adjusting for covariates, participants intermediate (OR: 0.805; 95% CI: 0.669–0.969) high 0.818; 0.684–0.979) 19.5% 18.2% less likely develop compared IVF. The probability spring 25.3% 0.747; 0.581–0.961) 23.3% 0.767; 0.597–0.985) lower middle elderly populations, respectively, whereas 36.5% 0.625; 0.474–0.824) 34.1% 0.659; 0.501–0.868). statistically significant (p < 0.05) gender, age, residence, living arrangement, marital status, economic situation, work, smoking, drinking, exercise, cooking ventilation, life satisfaction, self-rated health, hypertension, diabetes, heart disease, dementia, NO2. Interaction showed a interaction effect drinking (P 0.05). Higher is significantly associated risk LMM. Optimizing practices may mitigate burden adults, informing personalized health strategies.

Language: Английский

Citations

0
Association between urinary volatile organic compound metabolites and sarcopenia in the US general population: a cross-sectional NHANES study from 2011 to 2018 DOI Creative Commons
Wei Tang,

Tuotuo Chen,

Zixuan Luo

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 28, 2025

Volatile organic compound (VOC) is a prevalent form of pollutant that has been linked to various human ailments, yet their connection sarcopenia remains uncertain. This study seeks examine the potential association between exposure mixtures metabolites volatile compounds (mVOCs) and sarcopenia, while also investigating mediating effects oxidative stress inflammation. Data from 2011-2018 National Health Nutrition Examination Survey (NHANES) were utilized for analysis relationship mVOCs through logistic regression. The least absolute shrinkage selection operator (LASSO) regression model was employed identify key mVOCs, quantile-g computation (qgcomp) bayesian kernel machine (BKMR) models mVOC sarcopenia. Potential factors explored analysis. Of 2908 participants included in study, 246 individuals (8.5%) found have Logistic revealed five urinary VOC positively correlated with an increased risk identified LASSO method further analyzed using qgcomp, which showed 47% average increase when exposed mixture (OR = 1.47, 95% CI 1.14-1.91). Four components (DHBMA, 3HPMA, ATCA 3,4MHA) largest weight. BKMR results confirm this joint association. Furthermore, Mediation inflammation mediate In conclusion, our provides evidence suggesting heightened potentially serving as mediators relationship. It recommended additional cohort studies be conducted validate these findings.

Language: Английский

Citations

0
Health effect of multiple air pollutant mixture on sarcopenia among middle-aged and older adults in China DOI Creative Commons
Yinqiao Dong, Wangnan Cao, Jing Wei

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 281, P. 116634 - 116634

Published: June 25, 2024

As the global aging process accelerates, health challenges posed by sarcopenia among middle-aged and older adults are becoming increasingly prominent. However, available evidence on adverse effects of air pollution is limited, particularly in Western Pacific region. This study aimed to explore relationships multiple pollutants with related biomarkers using nationally representative database.

Language: Английский

Citations

2
Association of sarcopenia, ambient air pollution and cognitive function in a community-dwelling middle-aged and elderly Korean population: a community-based cohort study DOI Creative Commons
Jane Lee, Hae Dong Woo, Ji Hyun Kim

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(12), P. e092448 - e092448

Published: Dec. 1, 2024

Objectives To investigate the association of sarcopenia, exposure to medium-term long-term ambient particulate matter 2.5 µm and 10 (PM PM ) pollution cognitive function in a community-dwelling cohort middle-aged older adults South Korea. Design A community-based prospective study. Setting In Korean Genome Epidemiology Study (KoGES). Participants The participants were drawn from seventh follow-up visit conducted between 2015 2016 KoGES Ansung who had participated an ageing substudy. Outcome measures Cognitive was evaluated by version Mini-Mental State Examination (K-MMSE) decreased defined as K-MMSE score 23 or less. Results Of 2274 (mean age 70.1 years, 58.3% women mean annual levels 30.7 52.2 μg/m 3 , respectively), 8.7% (n=197) sarcopenic, 35.8% (n=814) possible sarcopenic 55.5% (n=1263) non-sarcopenic. predictors sarcopenia included body mass index, function, age, marital status, hypertension physical activity. Exposure for average duration 1 month years not selected predictor sarcopenia. with associated lower scores (β=−1.51, p<0.0001) compared those without (OR 2.34, 95% CI 1.56 3.52). effect modification on generally detected. Conclusions this observational study aged 50 older, function. However, did modify relationship

Language: Английский

Citations

0