Physicochemical Parameters’ Effects on the Freshwater Cyanobacterium Microcystis Sp. and Their Toxins DOI Creative Commons
Hichèm Nasri,

Loubna Ghodbane,

Amina Amrani

et al.

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Microcystis sp. are ubiquitous and highly prevalent Cyanobacteria found in freshwater ecosystems. They known for episodic, large-scale proliferations as “blooms”, which driven by factors such elevated nitrogen phosphorus concentrations, enhanced water column stability, increased temperatures. infamous producing a class of potent hepatotoxins “microcystins (MCs)”, exert their toxicity primarily through the inhibition serine/threonine protein phosphatases 1 (PP1) 2A (PP2A). This disrupts cellular signal transduction pathways affects numerous processes preventing dephosphorylation proteins. As result, there is significant disruption cytoskeleton, altered signaling, and, ultimately, cell apoptosis. Additionally, microcystins interfere with antioxidant defense mechanisms, causing oxidative stress generating reactive oxygen species (ROS). can lead to damage across various organs tissues, including liver, particularly susceptible microcystin toxicity. chapter provides comprehensive overview how physicochemical parameters influence proliferation production microcystins. It explores intricate relationship between environmental biosynthesis these toxins, thereby elucidating conditions that intensified production.

Language: Английский

Extensive Genomic Rearrangement of Catalase-Less Cyanobloom-Forming Microcystis aeruginosa in Freshwater Ecosystems DOI
Minkyung Kim, Jaejoon Jung, Wonjae Kim

et al.

The Journal of Microbiology, Journal Year: 2024, Volume and Issue: 62(11), P. 933 - 950

Published: Oct. 8, 2024

Language: Английский

Citations

0
Physicochemical Parameters’ Effects on the Freshwater Cyanobacterium Microcystis Sp. and Their Toxins DOI Creative Commons
Hichèm Nasri,

Loubna Ghodbane,

Amina Amrani

et al.

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Microcystis sp. are ubiquitous and highly prevalent Cyanobacteria found in freshwater ecosystems. They known for episodic, large-scale proliferations as “blooms”, which driven by factors such elevated nitrogen phosphorus concentrations, enhanced water column stability, increased temperatures. infamous producing a class of potent hepatotoxins “microcystins (MCs)”, exert their toxicity primarily through the inhibition serine/threonine protein phosphatases 1 (PP1) 2A (PP2A). This disrupts cellular signal transduction pathways affects numerous processes preventing dephosphorylation proteins. As result, there is significant disruption cytoskeleton, altered signaling, and, ultimately, cell apoptosis. Additionally, microcystins interfere with antioxidant defense mechanisms, causing oxidative stress generating reactive oxygen species (ROS). can lead to damage across various organs tissues, including liver, particularly susceptible microcystin toxicity. chapter provides comprehensive overview how physicochemical parameters influence proliferation production microcystins. It explores intricate relationship between environmental biosynthesis these toxins, thereby elucidating conditions that intensified production.

Language: Английский

Citations

0