Association between pollinosis and obstructive sleep apnea hypopnea syndrome in the US population: evidence from the NHANES database 2005–2018

BMC Pulmonary Medicine, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 13, 2025

Rhinobyon and inflammation associated with pollinosis may elevate the risk of obstructive sleep apnea hypopnea syndrome (OSAHS). However, exact nature this association remains unclear, particularly in large-scale populations. This study aimed to examine relationship between OSAHS using data from National Health Nutrition Examination Survey (NHANES). Data NHANES spanning 2005 2018 were analyzed. Three multivariate generalized linear models (GLMs) employed explore OSAHS: one unadjusted model, minimally adjusted fully model. Stratified analyses conducted assess impact other covariates on OSAHS. Additionally, incorporated K-Nearest Neighbors (KNN) smoothed curves refine analysis. The identified significant demographic differences groups factors such as pollinosis, age, gender, weight (WT), body mass index (BMI), waist circumference (WC), protein, fat. In three models, a consistent was observed Specifically, Model 1 showed an odds ratio (OR) 1.31 [95% confidence interval (CI): 1.16–1.48, P < 0.001], 2 revealed OR 1.35 (95% CI: 1.19–1.54, 0.001), 3 indicated 1.29 1.10–1.50, = 0.002), suggesting that remained robust despite inclusion covariates. Risk stratification confirmed factor for (OR 1.28, 95% 0.002). KNN model further supported utility diagnostic marker Smoothing also demonstrated positive correlation prevalence incidence. established OSAHS, emphasizing need vigilance monitoring managing individuals risk.

Language: Английский

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Research on the Momentum of Tennis Players Based on the XGBoost Model and GA-RF Model

Highlights in Science Engineering and Technology, Journal Year: 2025, Volume and Issue: 136, P. 307 - 315

Published: March 31, 2025

In this paper, to better represent an athlete's performance using momentum, paper proposed indicator system assess a player's at different stages of match. The article tested both LightGBM and XGBoost classification models. By comparing the accuracy, recall, precision training sets for models, found that achieved 91.8% all these metrics, while impressive 98.4%. Therefore, used feature importance derived from model determine weight indicators. After obtaining weighted indicators players, essay comprehensive calculation formula momentum changes player during also applied genetic algorithm-optimized random forest regression (GA-RF) predict real-time in Additionally, utilized SHAP interpret predictions, providing specific recommendations players prepare

Language: Английский

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FOSB is a key factor in the genetic link between inflammatory bowel disease and acute myocardial infarction: multiple bioinformatics analyses and validation

BMC Medical Genomics, Journal Year: 2025, Volume and Issue: 18(1)

Published: April 3, 2025

Inflammatory Bowel Disease (IBD), which includes Crohn's disease and ulcerative colitis, is associated with an increased risk of Acute Myocardial Infarction (AMI). The genetic mechanisms underlying this link are not well understood. We downloaded IBD AMI-related microarray datasets from the NCBI Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified analyzed using enrichment analysis Weighted Co-expression Network Analysis (WGCNA). Machine learning techniques, including LASSO, random forest, Boruta, employed to screen for hub genes. These validated through qRT-PCR Western blotting. Single-cell sequencing was used confirm findings. Additionally, potential therapeutic targets Connectivity Map (CMap) Five key genes-THBD, FOSB, ADGPR3, IL1R2, PLAUR-were as significantly involved in both AMI pathogenesis. A diagnostic model constructed these demonstrated high predictive accuracy. several drugs targeting identified, offering new avenues. This study highlights crucial role FOSB other comorbidity AMI. findings provide novel insights early diagnosis strategies, emphasizing importance further investigation into links.

Language: Английский

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The mediating roles of obesity indicators and serum albumin in the association of DEET exposure with depression and sleep disorders in adults: evidence from NHANES 2007-2016

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: May 6, 2025

Language: Английский

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Dissecting the connection between volatile organic compounds and cardiovascular disease: immune cell-mediated mechanism

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 298, P. 118297 - 118297

Published: May 14, 2025

Language: Английский

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