All roads lead to Rome: the plasticity of gut microbiome drives the extensive adaptation of the Yarkand toad-headed agama (Phrynocephalus axillaris) to different altitudes DOI Creative Commons

Jiang‐hao Du,

Peng Zheng, Weizhen Gao

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 8, 2025

The gut microbiome was involved in a variety of physiological processes and played key role host environmental adaptation. However, the mechanisms their response to altitudinal changes remain unclear. In this study, we used 16S rRNA sequencing LC-MS metabolomics investigate metabolism Yarkand toad-headed agama (Phrynocephalus axillaris) at different altitudes (-80 m 2000 m). results demonstrated that Firmicutes, Bacteroidetes, Proteobacteria were dominant phylum, Lachnospiraceae Oscillospiraceae most abundant family, low-altitude populations had higher richness than high-altitude populations; Akkermansiaceae appeared be enriched relative abundance tended increase with altitude. three P. axillaris clustered into two enterotypes, shared an enterotype dominated by Akkermansia, Kineothrix, Phocaeicola; intermediate-altitude Mesorhizobium, Bradyrhizobium. Metabolites amino acid lipid differed significantly altitudes. above suggest plasticity drives extensive adaptation multi-stress caused With global warming, recognizing adaptive capacity wide-ranging species altitude can help plan future conservation strategies.

Language: Английский

All roads lead to Rome: the plasticity of gut microbiome drives the extensive adaptation of the Yarkand toad-headed agama (Phrynocephalus axillaris) to different altitudes DOI Creative Commons

Jiang‐hao Du,

Peng Zheng, Weizhen Gao

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 8, 2025

The gut microbiome was involved in a variety of physiological processes and played key role host environmental adaptation. However, the mechanisms their response to altitudinal changes remain unclear. In this study, we used 16S rRNA sequencing LC-MS metabolomics investigate metabolism Yarkand toad-headed agama (Phrynocephalus axillaris) at different altitudes (-80 m 2000 m). results demonstrated that Firmicutes, Bacteroidetes, Proteobacteria were dominant phylum, Lachnospiraceae Oscillospiraceae most abundant family, low-altitude populations had higher richness than high-altitude populations; Akkermansiaceae appeared be enriched relative abundance tended increase with altitude. three P. axillaris clustered into two enterotypes, shared an enterotype dominated by Akkermansia, Kineothrix, Phocaeicola; intermediate-altitude Mesorhizobium, Bradyrhizobium. Metabolites amino acid lipid differed significantly altitudes. above suggest plasticity drives extensive adaptation multi-stress caused With global warming, recognizing adaptive capacity wide-ranging species altitude can help plan future conservation strategies.

Language: Английский

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