Radiotherapy-induced alterations in tumor microenvironment: metabolism and immunity DOI Creative Commons

Jinpeng Chen,

Sheng Wang, Yue Ding

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2025, Volume and Issue: 13

Published: April 28, 2025

Tumor metabolism plays a pivotal role in shaping immune responses within the tumor microenvironment influencing progression, evasion, and efficacy of cancer therapies. Radiotherapy has been shown to impact both modulation, often inducing activation through damage-associated molecular patterns STING pathway. In this study, we analyse particular characteristics tumour metabolic its effect on microenvironment. We also review changes that are induced by radiotherapy, with focus sensitisation effects radiotherapy. Our aim is contribute development research ideas field radiotherapy metabolic-immunological studies.

Language: Английский

Radiotherapy-induced alterations in tumor microenvironment: metabolism and immunity DOI Creative Commons

Jinpeng Chen,

Sheng Wang, Yue Ding

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2025, Volume and Issue: 13

Published: April 28, 2025

Tumor metabolism plays a pivotal role in shaping immune responses within the tumor microenvironment influencing progression, evasion, and efficacy of cancer therapies. Radiotherapy has been shown to impact both modulation, often inducing activation through damage-associated molecular patterns STING pathway. In this study, we analyse particular characteristics tumour metabolic its effect on microenvironment. We also review changes that are induced by radiotherapy, with focus sensitisation effects radiotherapy. Our aim is contribute development research ideas field radiotherapy metabolic-immunological studies.

Language: Английский

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