Molecular pathway approach in biotechnology DOI
Anton Buzdin,

Denis Kuzmin,

Ivana Jovčevska

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 339 - 352

Published: Dec. 6, 2024

Language: Английский

A topological review on protein–protein interactions: the development and promises in the era of omics DOI

Ananya Kapoor,

Sourjadeep Mondal,

Anubha Chaudhary

et al.

Journal of Proteins and Proteomics, Journal Year: 2024, Volume and Issue: 15(3), P. 523 - 544

Published: Aug. 2, 2024

Language: Английский

Citations

0
Editorial Overview: EJCB Special Issue - Cell Host-Pathogen Interactions DOI Creative Commons
Serge Mostowy, Theresia E. B. Stradal

European Journal of Cell Biology, Journal Year: 2024, Volume and Issue: unknown, P. 151462 - 151462

Published: Oct. 1, 2024

Language: Английский

Citations

0
Graph-based machine learning model for weight prediction in protein–protein networks DOI Creative Commons

Hajer Akid,

Kirsley Chennen, Gabriel Frey

et al.

BMC Bioinformatics, Journal Year: 2024, Volume and Issue: 25(1)

Published: Nov. 8, 2024

Proteins interact with each other in complex ways to perform significant biological functions. These interactions, known as protein-protein interactions (PPIs), can be depicted a graph where proteins are nodes and their edges. The development of high-throughput experimental technologies allows for the generation numerous data which permits increasing sophistication PPI models. However, despite progress, current networks remain incomplete. Discovering missing through techniques costly, time-consuming, challenging. Therefore, computational approaches have emerged valuable tools predicting interactions. In networks, is usually used model between proteins. An edge two indicates interaction, while absence an means interaction not or missed. this binary representation overlooks reliability when new ones. To address challenge, we propose novel approach link prediction weighted weights denote confidence scores. By leveraging from yeast Saccharomyces cerevisiae obtained STRING database, introduce that combines similarity-based algorithms aggregated score accurate purposes. Our significantly improves accuracy, surpassing traditional terms Mean Absolute Error, Relative Root Square Error. proposed holds potential improved accuracy PPIs, crucial better understanding underlying processes.

Language: Английский

Citations

0
Getting started with the molecular pathway analysis DOI
Anton Buzdin, Xinmin Li

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 179 - 202

Published: Dec. 6, 2024

Language: Английский

Citations

0
Molecular data for the pathway analysis DOI
Xinmin Li, Anton Buzdin

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 43 - 62

Published: Dec. 6, 2024

Language: Английский

Citations

0
Molecular pathway approach in biotechnology DOI
Anton Buzdin,

Denis Kuzmin,

Ivana Jovčevska

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 339 - 352

Published: Dec. 6, 2024

Language: Английский

Citations

0