Biological importance of bioactive phytochemical ‘Cimifugin’ as potential active pharmaceutical ingredients against human disorders: A natural phytochemical for new therapeutic alternatives DOI Creative Commons
Dinesh Kumar Patel

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2023, Volume and Issue: 7, P. 100232 - 100232

Published: March 4, 2023

Herbal medicines have been used in medicine against numerous kinds of human disorders and associated secondary complications since a very early age. huge biological potential mainly due to its therapeutic fewer side effects. composed with plant their derived pure phytochemicals. Coumarins are oxygenated heterocyclic class phytochemical, found be present the plants, bacteria fungi. were Ferulago campestris, Murraya paniculata, Aegle marmelos tonka beans. Cimifugin is an important coumarin phytochemical Saposhnikovia divaricata Cimicifuga racemosa. Scientific data medicinal importance, pharmacological activities analytical aspects cimifugin collected from Science Direct, PubMed, Google Scholar, Scopus analyzed work order know cimifugin. The importance furanocoumarins coumarins has also discussed understand Pharmacological different targets investigated work. However, techniques for determination samples Biological treatment types effects on hepatic disorders, bone disease, allergic reaction, inflammatory psoriasis, cancer, neurodegenerative diseases. Further, molecular mechanisms underlying curative presented. Analytical developments presented this will future.

Language: Английский

Synthesis and characterization of benzotriazole-functionalized 1,3,5-triazine-based luminescent high-performance polymers and their antibacterial efficacy DOI

Radha R. Rajput,

Saurabh K. Patel

Journal of Macromolecular Science Part A, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: Feb. 5, 2025

A straightforward approach in fabricating novel thermally stable fluorescent polymeric materials by incorporating 1,3,5-triazine as a core moiety, coumarin fluorophore and 1,2,3-benzotriazole synthetic auxiliary resulting the synthesis of 2-(1,2,3-benztriazolo)-4,6-bis-(7-hydroxy-coumarin-4-acetyl chloride)-s-triazine (4) key monomer. range aromatic aliphatic diols were introduced using cetrimide initiator under polar aprotic solvent to synthesize desired polyesters 5(a–j). Incorporation bulky pendent group structure increases thermal stability solubility polyesters. The intrinsic, reduced inherent viscosities determined Huggins Kraemer's method. detailed kinetic study based on thermogravimetric analysis has been carried out activation energy was calculated Broido, Horowitz Metzger methods. Moreover, FTIR, 1H NMR, photoluminescent behavior antibacterial efficacy have also evaluated. This contributes development multifunctional with fluorescence, capabilities, such bioimaging, drug delivery antimicrobial coatings for medical devices. selection these components is guided their distinctive features synergistic potential production high-performance polymers.

Language: Английский

Citations

0
Regioselective C3-N alkylation of coumarins under solvent-free conditions: a graphene oxide nanosheet promoted novel strategy for C-N bond formation via azide-alkene 1,3-dipolar cycloaddition reaction DOI

Nazia Kausar,

Mohd Afzal, Abdullah Alarifi

et al.

Chemical Papers, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Language: Английский

Citations

0
Exploring β-carboline hybrids and their derivatives: A review on synthesis and anticancer efficiency DOI

Nur Fatihah Sulaiman,

Siti Zafirah Zulkifli, Aimi Suhaily Saaidin

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 288, P. 117412 - 117412

Published: Feb. 18, 2025

Language: Английский

Citations

0
Green preparation of cu immobilized on CaZnFe2O4 MNPs (CaZnFe2O4@OLE-cu) as a biocatalyst in the synthesis of new coumarin derivatives DOI Creative Commons

Masoumeh Pouryavar,

Akbar Mobinikhaledi,

Najmieh Ahadi

et al.

Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102161 - 102161

Published: Feb. 1, 2025

Language: Английский

Citations

0
Biological importance of bioactive phytochemical ‘Cimifugin’ as potential active pharmaceutical ingredients against human disorders: A natural phytochemical for new therapeutic alternatives DOI Creative Commons
Dinesh Kumar Patel

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2023, Volume and Issue: 7, P. 100232 - 100232

Published: March 4, 2023

Herbal medicines have been used in medicine against numerous kinds of human disorders and associated secondary complications since a very early age. huge biological potential mainly due to its therapeutic fewer side effects. composed with plant their derived pure phytochemicals. Coumarins are oxygenated heterocyclic class phytochemical, found be present the plants, bacteria fungi. were Ferulago campestris, Murraya paniculata, Aegle marmelos tonka beans. Cimifugin is an important coumarin phytochemical Saposhnikovia divaricata Cimicifuga racemosa. Scientific data medicinal importance, pharmacological activities analytical aspects cimifugin collected from Science Direct, PubMed, Google Scholar, Scopus analyzed work order know cimifugin. The importance furanocoumarins coumarins has also discussed understand Pharmacological different targets investigated work. However, techniques for determination samples Biological treatment types effects on hepatic disorders, bone disease, allergic reaction, inflammatory psoriasis, cancer, neurodegenerative diseases. Further, molecular mechanisms underlying curative presented. Analytical developments presented this will future.

Language: Английский

Citations

10