The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
90(1), P. 908 - 912
Published: Dec. 31, 2024
A
three-component
reaction
of
alkenyl
thianthrenium
salts,
cyclopropan-1-ols
and
DABCO·(SO2)2
under
catalyst-
additive-free
conditions,
is
accomplished.
This
sulfonylation
with
the
insertion
sulfur
dioxide
works
efficiently
very
mild
leading
to
a
wide
range
1-substituted
vinyl
sulfones
in
moderate
good
yields.
In
this
protocol,
scope
generality
salts
cyclopropyl
alcohols
demonstrated.
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
9(14), P. 3781 - 3785
Published: Jan. 1, 2022
A
photoredox-catalyzed
reaction
of
thianthrenium
salts,
hydrazines
and
DABCO·(SO
2
)
is
accomplished,
providing
diverse
arenesulfonohydrazides
in
moderate
to
good
yields
under
mild
conditions.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(13), P. 9672 - 9680
Published: June 13, 2024
A
three-component
reaction
of
1-(1H-indol-1-yl)isoquinolines
or
1-(pyridin-2-yl)-1H-indoles,
DABCO·(SO2)2,
and
thianthrenium
salts
under
synergistic
photoredox
palladium
catalysis
is
accomplished.
This
direct
C–H
bond
sulfonylation
indoles
with
the
insertion
sulfur
dioxide
mild
conditions
works
efficiently,
giving
rise
to
a
wide
range
2-sulfonated
in
moderate
good
yields
conditions.
In
this
protocol,
generality
aryl/alkyl
demonstrated
as
well.
radical
process
combined
proposed.
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
10(4), P. 866 - 871
Published: Dec. 21, 2022
Synthesis
of
β-azido
alkylsulfones
through
a
photoredox-catalyzed
azido
sulfonylation
alkenes
with
DABCO·(SO
2
)
,
trimethylsilyl
azide
and
alkyl
thianthrenium
salts
is
developed.
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
10(1), P. 92 - 98
Published: Nov. 11, 2022
Synthesis
of
sulfonyl-containing
axially
chiral
styrenes
through
a
catalytic
asymmetric
reaction
4-substituted
Hantzsch
esters,
sodium
hydrogen
sulfite
and
1-(arylethynyl)naphthalen-2-ols
is
reported.
Expert Opinion on Drug Discovery,
Journal Year:
2023,
Volume and Issue:
19(2), P. 239 - 251
Published: Nov. 18, 2023
Introduction
Vinyl
sulfones
are
a
special
sulfur-containing
structural
unit
that
have
attracted
considerable
attention,
owing
to
their
important
role
in
serving
as
key
motifs
of
various
biologically
active
compounds
well
versatile
building
blocks
for
organic
transformations.
The
synthetic
strategy
vinyl
sulfone
derivatives
has
been
substantially
upgraded
over
the
past
30
years,
and
wide
application
this
functional
group
drug
design
discovery
promoted.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
365(4), P. 555 - 567
Published: Jan. 18, 2023
Abstract
A
direct,
visible‐light‐mediated,
radical‐cascade
addition/sulfonylation/cyclization
reaction
with
DABCO
⋅
(SO
2
)
and
thianthrenium
salts
is
reported
herein.
This
protocol
provides
operationally‐convenient
access
to
various
sulfonated
functionalized
indole
[2,1‐a]
isoquinolines
under
mild
conditions.
transformation
features
high
functional‐group
tolerance,
operational
ease,
broad
substrate
scope.
Preliminary
studies
reveal
that
the
method
undergoes
a
radical
pathway.
magnified
image
