Modified SPPS Protocol for the Synthesis of Novel Antimicrobial Peptides DOI
Dinesh Kumar Anguraj,

Shivani Chaudhary,

Mukesh Pasupuleti

et al.

International Journal of Peptide Research and Therapeutics, Journal Year: 2025, Volume and Issue: 31(4)

Published: April 21, 2025

Language: Английский

Two Step Synthesis of Octreotide-doxorubicin Conjugates Based on Disulfide Bond Linker DOI

Qian-Yao Yu,

Ming Meng,

Jing-Fang Yao

et al.

Acta Chimica Sinica, Journal Year: 2025, Volume and Issue: 83(4), P. 341 - 341

Published: Jan. 1, 2025

Language: Английский

Citations

0
On-Resin Acetamidomethyl (Acm) Removal and Disulfide Formation in Cysteinyl Peptides Using N-Chlorosuccinimide (NCS) in the Presence of Other Cys-Protecting Groups DOI Open Access
Amit Chakraborty, Fernando Alberício, Beatriz G. de la Torre

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2523 - 2523

Published: March 11, 2025

Acetamidomethyl (Acm)-protected cysteine derivatives are essential components of multi-disulfide synthesis, particularly due to the availability multimodal removal conditions for Acm protection. Most these harsh and commonly used remove protection at last step regioselective synthesis a multi-disulfide, implying that is performed in absence other Cys thiol protections. In this context, N-chlorosuccinimide (NCS)-mediated concomitant disulfide bridge formation provides fast reliable way synthesize multi-disulfides. present study, we demonstrate NCS-mediated bond can be presence Interestingly, removed with NCS without affecting Trt group, which also I2. Later, successfully employ NCS-based method peptides like α-conotoxin SI.

Language: Английский

Citations

0
A Comprehensive Review of Magnetic Nanocatalysts for C−S, C−Se Bond Formation DOI Creative Commons
Radwan Ali, Jianlin Han, Mosstafa Kazemi

et al.

ChemistryOpen, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract This review manuscript examines magnetic nanocatalysts and their pivotal role in forming carbon‐sulfur (C−S) carbon‐selenium (C−Se) bonds. The study delves into the latest advancements synthesis, characterization, application of nanocatalysts, highlighting unique advantages, including enhanced catalytic activity, superior selectivity, easy recovery through separation, which align with principles green chemistry. Through a critical analysis recent research findings, this also explores mechanistic pathways facilitated by these offering insights operational efficiency potential for recyclability. aims not only to catalog current achievements burgeoning field but identify challenges propose future directions developing more efficient, sustainable, versatile systems C−S C−Se bond formation. By encompassing broad spectrum ranging from bare magnets functionalized composite materials, is comprehensive resource researchers engaged organic catalysis, sustainable

Language: Английский

Citations

0
A comprehensive investigation into the spectroscopic properties, solvent effects on electronic properties, structural characteristics, topological insights, reactive sites, and molecular docking of racecadotril: A potential antiviral and antiproliferative agent DOI

R. Manjula,

C. Pavithra,

A. Ram Kumar

et al.

Journal of the Indian Chemical Society, Journal Year: 2025, Volume and Issue: unknown, P. 101702 - 101702

Published: April 1, 2025

Language: Английский

Citations

0
Modified SPPS Protocol for the Synthesis of Novel Antimicrobial Peptides DOI
Dinesh Kumar Anguraj,

Shivani Chaudhary,

Mukesh Pasupuleti

et al.

International Journal of Peptide Research and Therapeutics, Journal Year: 2025, Volume and Issue: 31(4)

Published: April 21, 2025

Language: Английский

Citations

0