The latest developments in the design and discovery of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of HIV DOI
Junyi Li, Bing Ye, Shenghua Gao

et al.

Expert Opinion on Drug Discovery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 18

Published: Oct. 13, 2024

Introduction This review encapsulates the recent strides in development of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV treatment, focusing on novel structural designs that promise to overcome limitations existing therapies, such as drug resistance and toxicity.

Language: Английский

Discovery of Novel Fused-heterocycle-bearing Diarypyrimidine Derivatives as HIV-1 Potent NNRTIs Targeting Tolerant Region I for Enhanced Antiviral Activity and Resistance Profile DOI

Jiaojiao Dai,

Xiangyi Jiang, Heng Gao

et al.

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 281, P. 117033 - 117033

Published: Nov. 7, 2024

Language: Английский

Citations

2
The latest developments in the design and discovery of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of HIV DOI
Junyi Li, Bing Ye, Shenghua Gao

et al.

Expert Opinion on Drug Discovery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 18

Published: Oct. 13, 2024

Introduction This review encapsulates the recent strides in development of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV treatment, focusing on novel structural designs that promise to overcome limitations existing therapies, such as drug resistance and toxicity.

Language: Английский

Citations

1