New Cu(II), Cu(I) and Ag(I) Complexes of Phenoxy-Ketimine Schiff Base Ligands: Synthesis, Structures and Antibacterial Activity DOI Creative Commons
Miriam Caviglia, Zhenzhen Li, Carlo Santini

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(9), P. 1893 - 1893

Published: April 24, 2025

Two phenoxy-ketimines ligands, 2-(1-(benzylimino)ethyl)phenol (HLBSMe) and 2-((benzylimino)(phenyl)methyl)phenol (HLBSPh), were synthesized used as supporting ligands of new copper(II), copper(I), silver(I) complexes. In order to confer different solubility properties the metal complexes stabilize Cu Ag in their +1 oxidation state, lipophilic triphenylphosphine (PPh3) hydrophilic 1,3,5-triaza-7-phosphaadamantane (PTA) selected co-ligands syntheses Cu(I) Ag(I) All compounds characterized by CHN analysis, NMR, FT-IR spectroscopy, electrospray ionization mass spectrometry (ESI-MS); molecular structure copper(II) complex [Cu(LBSPh)2] was also determined single-crystal X-ray diffraction. Finally, antibacterial activity complexes, Schiff base phosphane co-ligands, assessed determining minimum inhibitory concentration (MIC) bactericidal (MBC) against Gram-negative (Escherichia coli) Gram-positive bacteria (Staphylococcus aureus).

Language: Английский

Ruthenium(ii) and copper(ii) polyamine complexes as promising antitumor agents: synthesis, characterization, and biological evaluation DOI Creative Commons

Yoel Garrosa-Miró,

Laura Muñoz‐Moreno, Gerardino D’Errico

et al.

Dalton Transactions, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

New Ru( ii ) and Cu( complexes with polyamine ligands show high cytotoxicity against prostate cancer cells, inhibit adhesion/migration, reduce ROS, offering promising, selective, less toxic alternatives to cisplatin.

Language: Английский

Citations

0
New Cu(II), Cu(I) and Ag(I) Complexes of Phenoxy-Ketimine Schiff Base Ligands: Synthesis, Structures and Antibacterial Activity DOI Creative Commons
Miriam Caviglia, Zhenzhen Li, Carlo Santini

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(9), P. 1893 - 1893

Published: April 24, 2025

Two phenoxy-ketimines ligands, 2-(1-(benzylimino)ethyl)phenol (HLBSMe) and 2-((benzylimino)(phenyl)methyl)phenol (HLBSPh), were synthesized used as supporting ligands of new copper(II), copper(I), silver(I) complexes. In order to confer different solubility properties the metal complexes stabilize Cu Ag in their +1 oxidation state, lipophilic triphenylphosphine (PPh3) hydrophilic 1,3,5-triaza-7-phosphaadamantane (PTA) selected co-ligands syntheses Cu(I) Ag(I) All compounds characterized by CHN analysis, NMR, FT-IR spectroscopy, electrospray ionization mass spectrometry (ESI-MS); molecular structure copper(II) complex [Cu(LBSPh)2] was also determined single-crystal X-ray diffraction. Finally, antibacterial activity complexes, Schiff base phosphane co-ligands, assessed determining minimum inhibitory concentration (MIC) bactericidal (MBC) against Gram-negative (Escherichia coli) Gram-positive bacteria (Staphylococcus aureus).

Language: Английский

Citations

0