Obstructive Sleep Apnea in Women DOI

Atul Khullar,

Jennifer Swainson

Canadian Women s Health Today, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Obstructive sleep apnea (OSA) is a common disease with large public health burden. Due to several anatomical and physiological differences, OSA has traditionally thought be much less in women than men. These differences include variations craniofacial anatomy, sex hormone greater peripheral fat distribution, as well having shorter collapsible airways respiratory drive instability. However the recruitment bias from clinical samples early studies fostered this difference an exaggerated degree. One community-based sample of adults aged 21–80 indicated point prevalence clinically significant sleepiness 3–7% males 2–5% females. Another larger worldwide community study lifetime 27.3% men 22.5% narrower population 30–69. Both show approximate 1:5–1 ratio which lower that previous showing 9 or 10:1. In pediatric elderly populations, male female close equal.

Language: Английский

Influence of Obstructive Sleep Apnea on Oxidative Stress in Pregnancy DOI Open Access

Laura Cànaves-Gómez,

Paloma Giménez, Ainhoa Álvarez Ruiz De Larrínaga

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 886 - 886

Published: Jan. 21, 2025

Obstructive sleep apnea (OSA) is common during pregnancy and linked to adverse outcomes. While oxidative stress a proposed pathogenic mechanism, evidence in pregnant populations remains limited. This multicenter, prospective study evaluated through protein carbonyl levels 171 women 86 cord blood samples. Polysomnography (PSG) performed categorized participants with the apnea–hypopnea index (AHI) OSA, rapid eye movement (REM) supine OSA. Protein were measured by dinitrophenyl hydrazine (DNPH) method. No significant differences found maternal or between OSA non-OSA groups, REM subgroups. Interestingly, shorter (AH) length showed both higher lower nocturnal oxygen saturation. Overall, was not associated increased as levels. However, duration hypoxia may influence stress, pointing complex relationship pregnancy, beyond traditional metrics like AHI. Future studies should explore additional biomarkers diverse molecular pathways that could play role, special attention emerging factors such hypoxic burden elucidate interrelationships more comprehensively.

Language: Английский

Citations

0
Obstructive Sleep Apnea in Women DOI

Atul Khullar,

Jennifer Swainson

Canadian Women s Health Today, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Obstructive sleep apnea (OSA) is a common disease with large public health burden. Due to several anatomical and physiological differences, OSA has traditionally thought be much less in women than men. These differences include variations craniofacial anatomy, sex hormone greater peripheral fat distribution, as well having shorter collapsible airways respiratory drive instability. However the recruitment bias from clinical samples early studies fostered this difference an exaggerated degree. One community-based sample of adults aged 21–80 indicated point prevalence clinically significant sleepiness 3–7% males 2–5% females. Another larger worldwide community study lifetime 27.3% men 22.5% narrower population 30–69. Both show approximate 1:5–1 ratio which lower that previous showing 9 or 10:1. In pediatric elderly populations, male female close equal.

Language: Английский

Citations

0