Paternal Effects in Mammalian Reproduction: Functional, Environmental, and Clinical Relevance of Sperm Components in Early Embryos and Beyond
Molecular Reproduction and Development,
Journal Year:
2025,
Volume and Issue:
92(3)
Published: March 1, 2025
ABSTRACT
In
addition
to
widely
recognized
contributions
of
the
paternal
genome,
centriole,
and
oocyte‐activation
factors,
sperm
deliver
a
wide
range
macromolecules
fertilized
embryo.
The
impacts
these
factors
on
embryo,
progeny,
even
subsequent
generations
have
become
increasingly
apparent,
along
with
an
understanding
extensive
potential
for
male
health
environmental
exposures
exert
both
immediate
long‐term
mammalian
reproduction.
Available
data
reveal
that
interact
regulate
actions
oocyte
as
well
exerting
additional
direct
effects
early
This
review
provides
summary
nature
mechanisms
in
embryos,
susceptibility
components
diverse
approaches
mitigate
adverse
such
exposures.
Language: Английский
Climate Change and Human Health: Time to Recognize the New Threat
Y. J. Anupama
No information about this author
APIK Journal of Internal Medicine,
Journal Year:
2024,
Volume and Issue:
13(1), P. 13 - 22
Published: Dec. 27, 2024
Climate
change
(CC)
is
an
important,
emerging
global
threat
to
human
health.
The
temperature
on
the
surface
of
earth
has
been
increasing
rapidly
over
last
few
decades.
Global
warming
(GW)
cascading
effects
environment
affecting
rainfall,
precipitation,
and
sea
water
levels.
Much
GW
due
activity
linked
large
scale
industrialization,
urbanization,
combustion
fossil
fuels.
essential
requisites
for
life
namely,
clean
air,
water,
good
quality
food
are
getting
depleted
rapidly.
air
pollution
influences
quantity.
These
changes
compromise
many
aspects
health
resulting
in
malnutrition,
infections,
rising
burden
cardiometabolic
diseases.
There
also
socioeconomic
consequences
CC
extreme
weather
events
which
have
impact
security
mental
Efforts
combat
involve
measures
control
primarily.
Global,
loco-regional
individual
efforts
at
adaptation
mitigation
must
be
carried
out
a
war-footing
prevent
surge
Language: Английский