Deleted Journal,
Journal Year:
2024,
Volume and Issue:
1(1)
Published: July 21, 2024
Abstract
Aromatic
natural
products
are
important
for
improving
human
health
and
quality
of
life.
Large-scale
availability
these
compounds
from
plants
is
limited
by
low
yield
cumbersome
extraction.
Building
high-performance
microbial
cell
factories
to
produce
aromatic
means
metabolic
engineering
synthetic
biology
a
viable
option.
In
the
context
climate
change
global
resource
scarcity,
choosing
solar-powered
carbon-fixing
cyanobacteria
instead
chemical
heterotrophic
microorganisms
might
be
more
progressive
better
solution.
this
review,
we
summarize
principal
strategies
production
in
engineered
cyanobacteria,
including
regulation
metabolism,
optimization
pathway,
culture
process
development,
cooperation,
highlighting
potential
microbe
as
novel
chassis
cell.
Discover Chemistry.,
Journal Year:
2025,
Volume and Issue:
2(1)
Published: March 26, 2025
In
recent
years,
microbial
infections
have
become
the
most
common
and
leading
cause
of
death
worldwide.
From
them,
Gram-positive
bacterial
strain
Staphylococcus
aureus
is
a
highly
effective
pathogen
that
can
infect
almost
every
human
body
tissue,
from
minor
skin
diseases
to
life-threatening
infections.
Antibiotics
are
generally
used
treat
infections,
but
due
their
excessive
careless
usage,
microorganisms
gradually
developed
resistance
them.
Therefore,
it
necessary
develop
novel
drugs
minimize
drug
resistance.
Many
available
in
market
they
not
as
before.
Currently,
coumarin
derivatives
regarded
medicinal
chemistry
favored
by
new
researchers
diverse
pharmaceutical
properties,
including
antibacterial,
anticancer,
antitubercular,
antioxidant,
etc.
It
also
possesses
antibiotic
qualities
well.
Coumarines
commercially
long
been
utilized
clinical
treatment.
These
therapeutic
properties
help
antimicrobial
agents
Hence,
this
review
article
provides
significant
attention
developments
structure–activity
relationships
(SAR)
C-3
substituted
combat
infection
caused
S.
aureus.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
1(1)
Published: July 21, 2024
Abstract
Aromatic
natural
products
are
important
for
improving
human
health
and
quality
of
life.
Large-scale
availability
these
compounds
from
plants
is
limited
by
low
yield
cumbersome
extraction.
Building
high-performance
microbial
cell
factories
to
produce
aromatic
means
metabolic
engineering
synthetic
biology
a
viable
option.
In
the
context
climate
change
global
resource
scarcity,
choosing
solar-powered
carbon-fixing
cyanobacteria
instead
chemical
heterotrophic
microorganisms
might
be
more
progressive
better
solution.
this
review,
we
summarize
principal
strategies
production
in
engineered
cyanobacteria,
including
regulation
metabolism,
optimization
pathway,
culture
process
development,
cooperation,
highlighting
potential
microbe
as
novel
chassis
cell.
