From Preformulative Design to in Vivo Tests: A Complex Path of Requisites and Studies for Nanoparticle Ocular Application. Part 2: In Vitro, Ex Vivo, and In Vivo Studies DOI
Cinzia Cimino, Lorena Bonilla, Federica Conti

et al.

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(12), P. 6062 - 6099

Published: Nov. 8, 2024

The incidence of ocular pathologies is constantly increasing, as the interest researchers in developing new strategies to ameliorate treatment these conditions. Nowadays, drug delivery systems are considered among most relevant approaches due their applicability a great variety inner and outer eye through painless topical administrations. design such nanocarriers requires deep study many aspects related administration route but also consideration authorities pharmacopeial requirements, order achieve clinical outcome. On bases, scope this review describe path analyses that could be performed on nanoparticles, along with assessment for ophthalmic treatments. Preformulation studies, physicochemical technological characterization, preliminary noncellular

Language: Английский

From Preformulative Design to in Vivo Tests: A Complex Path of Requisites and Studies for Nanoparticle Ocular Application. Part 2: In Vitro, Ex Vivo, and In Vivo Studies DOI
Cinzia Cimino, Lorena Bonilla, Federica Conti

et al.

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(12), P. 6062 - 6099

Published: Nov. 8, 2024

The incidence of ocular pathologies is constantly increasing, as the interest researchers in developing new strategies to ameliorate treatment these conditions. Nowadays, drug delivery systems are considered among most relevant approaches due their applicability a great variety inner and outer eye through painless topical administrations. design such nanocarriers requires deep study many aspects related administration route but also consideration authorities pharmacopeial requirements, order achieve clinical outcome. On bases, scope this review describe path analyses that could be performed on nanoparticles, along with assessment for ophthalmic treatments. Preformulation studies, physicochemical technological characterization, preliminary noncellular

Language: Английский

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