THE EARLY STAGE ADENOCARCINOMA OF THE GALLBLADDER INCIDENTALLY DIAGNOSED DOI Creative Commons
Octavian Cătălin Ciobotaru, Elena Stamate, Gabriela Stoleriu

et al.

Published: Sept. 15, 2024

Aim of the study: Adenocarcinoma gallbladder diagnosed incidentally can reach up to 50% cancer cases, but with a life expectancy double that those non-incidentally. Gallstones represent risk factor for this pathology. Material and method. We conducted retrospective study, between 2011-2016, on number 341 patients, over 18 years old, cholecystectomized bladder lithiasis. Acute cholecystitis, patients acute or chronic inflammatory diseases, open surgical interventions, choledocholithiasis, cholelithiasis associated liver pathology were excluded. Results: The histopathological examination identified 8 cases adenocarcinoma, 2 well differentiated, 6 moderately differentiated. represented 2.35% total studied. average age appearance well-differentiated adenocarcinoma was lower than differentiated (50.00 ± 2.828 vs 58.00 3.347). most frequent in female (87.5%). Urban origin common, only 12.5% neoplasms came from rural areas. Conclusions: All gallstones should undergo cholecystectomy followed by order identify an early gallbladder.

Language: Английский

Case report: Cancer-free survival after chemotherapy, targeted immunotherapy combination with proton therapy following space making technique in a patient with cholangiocarcinoma after choledochal cyst resection DOI Creative Commons
Jian Kong, Qi Xia, Li Xu

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 8, 2025

Choledochal cysts (CCs) are rare cystic dilations of the intrahepatic and/or extrahepatic bile ducts. Malignancies arising during follow-up after excision CCs have been reported in both children and adults, with no typical time frame for malignancy development. We present a case patient diagnosed 36 years ago, who underwent resection subsequently developed cancer. The received chemotherapy, targeted therapy, immunotherapy, efficacy evaluation indicating state stable disease. Considering tumor resistance continuous systemic therapy an unresectable tumor, proton was selected next treatment. To prevent gastrointestinal side effects bile-enteric anastomosis dismantled, greater omentum strip used to fill subhepatic space, creating barrier between biliary duct intestine. successfully without any complications. As CC-associated poses lifelong risk even complete resection, surveillance should be maintained throughout period. Comprehensive treatment adopted improve prognosis CC resection.

Language: Английский

Citations

0
Biliary tract cancers: a descriptive study in the population treated at the Centre Hospitalier Universitaire de Sherbrooke (CHUS) between 2009 and 2021 DOI Creative Commons

Belinda Jiao,

Mandy Malick,

Samuel Lemaire‐Paquette

et al.

Academia oncology., Journal Year: 2025, Volume and Issue: 2(1)

Published: Feb. 19, 2025

Introduction: Biliary tract cancers (BTCs) are associated with a poor prognosis and lack of standardized management guidelines in Canada, resulting variable care influenced by age, ethnicity, region. This study analyzes BTC demographics, diagnostics, treatment modalities, survival outcomes at the Centre Hospitalier Universitaire de Sherbrooke (CHUS), Quebec. Methods: A retrospective from 2009 to 2021 included patients aged 18 older diagnosed carcinoma-type BTCs treated CHUS. Results: total 218 were our study. The median age diagnosis was 70.7 years, 48.6% being male 51.4% female. In population, extrahepatic cholangiocarcinomas most frequently (31.7%), followed intrahepatic (29.8%), gallbladder carcinomas (19.7%), Ampulla Vater (16.1%). Identifiable risk factors very rare. Computed tomography (CT) scans primary diagnostic tool (98.1%). Surgical resection performed 35.3% patients, 40.4% received chemotherapy. overall 10.2 months, 1-year rate 46%. Patients cancer had longest 55 months. improved for all biliary subtypes, reaching 52 Conclusions: CHUS show diverse demographics types, mirroring national trends. Early detection surgical enhance survival. Ongoing research is essential improve explore its complex causes.

Language: Английский

Citations

0
Liver Metastases from Colorectal Cancer: a joint ESSO–EAHPBA–UEMS core curriculum collaboration DOI Creative Commons
Lucía Carrión-Álvarez, Florian Primavesi, Kjetil Søreide

et al.

European Journal of Surgical Oncology, Journal Year: 2025, Volume and Issue: 51(6), P. 109728 - 109728

Published: Feb. 25, 2025

Language: Английский

Citations

0
Comparative diagnostic performance of [68 Ga]Ga-FAPI PET/CT and [18 F]FDGPET/CT in biliary tract cancers: a systematic review and meta-analysis DOI
Ahmed Msherghi, Mohannad Abuajamieh,

Moad Ekreer

et al.

European Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Language: Английский

Citations

0
Preoperative management and resectability criteria in perihilar cholangiocarcinoma DOI
Christian Sturesson, Kjetil Søreide

British journal of surgery, Journal Year: 2025, Volume and Issue: 112(4)

Published: March 28, 2025

Language: Английский

Citations

0
THE EARLY STAGE ADENOCARCINOMA OF THE GALLBLADDER INCIDENTALLY DIAGNOSED DOI Creative Commons
Octavian Cătălin Ciobotaru, Elena Stamate, Gabriela Stoleriu

et al.

Published: Sept. 15, 2024

Aim of the study: Adenocarcinoma gallbladder diagnosed incidentally can reach up to 50% cancer cases, but with a life expectancy double that those non-incidentally. Gallstones represent risk factor for this pathology. Material and method. We conducted retrospective study, between 2011-2016, on number 341 patients, over 18 years old, cholecystectomized bladder lithiasis. Acute cholecystitis, patients acute or chronic inflammatory diseases, open surgical interventions, choledocholithiasis, cholelithiasis associated liver pathology were excluded. Results: The histopathological examination identified 8 cases adenocarcinoma, 2 well differentiated, 6 moderately differentiated. represented 2.35% total studied. average age appearance well-differentiated adenocarcinoma was lower than differentiated (50.00 ± 2.828 vs 58.00 3.347). most frequent in female (87.5%). Urban origin common, only 12.5% neoplasms came from rural areas. Conclusions: All gallstones should undergo cholecystectomy followed by order identify an early gallbladder.

Language: Английский

Citations

0