Frontiers in Microbiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 7, 2023
Ketoprofen,
a
bicyclic
non-steroidal
anti-inflammatory
drug
commonly
used
in
human
and
veterinary
medicine,
has
recently
been
cited
as
an
environmental
contaminant
that
raises
concerns
for
ecological
well-being.
It
poses
growing
threat
due
to
its
racemic
mixture,
enantiomers,
transformation
products,
which
have
ecotoxicological
effects
on
various
organisms,
including
invertebrates,
vertebrates,
plants,
microorganisms.
Furthermore,
ketoprofen
is
bioaccumulated
biomagnified
throughout
the
food
chain,
threatening
ecosystem
function.
Surprisingly,
despite
these
concerns,
not
currently
considered
priority
substance.
While
targeted
eco-pharmacovigilance
proposed,
data
pharmaceutical
are
limited
incomplete.
This
review
aims
provide
comprehensive
summary
of
most
recent
findings
(from
2017
March
2023)
regarding
global
distribution
environment,
ecotoxicity
towards
aquatic
animals
available
removal
methods.
Special
emphasis
placed
understanding
how
affects
microorganisms
play
pivotal
role
Earth’s
ecosystems.
The
broadly
covers
approaches
biodegradation,
whole-cell
fungal
bacterial
systems
well
enzyme
biocatalysts.
Additionally,
it
explores
potential
adsorption
by
algae
phytoremediation
removing
ketoprofen.
will
be
interest
wide
range
readers,
ecologists,
microbiologists,
policymakers,
those
concerned
about
pollution.
Desalination and Water Treatment,
Journal Year:
2024,
Volume and Issue:
317, P. 100197 - 100197
Published: Jan. 1, 2024
Two
new
bio-adsorbents
were
successfully
synthesized
by
doping
method
with
zinc
chloride
salt
(ZnCl2)
of
raw
artichoke
leaves
(RAL)
and
orange
peels
waste
(ROP).
Different
analysis
techniques
(i.e.
BET,
SEM,
XRD,
FTIR)
used
for
characterizing
the
materials.
Ketoprofen
(KTF)
nonsteroidal
anti-inflammatory
drug
was
effectively
removed
from
water
using
bio-adsorbents,
under
different
operating
conditions.
The
specific
surface
areas
increased
1009.960
997.816
m2/g
ROP
RAL
natural
materials,
respectively,
to
1511.278
3415.951
ROP-
RAL-doped
More
interestingly,
maximum
removals
90%
96%
obtained
against
null
removal
kinetic
study
shows
that
pseudo-second
order
model
simulated
adequately
data
R2
superior
99%.
A
DOE
based
on
(23)
full
factorial
design
evaluate
effect
pH,
bio-adsorbent
dosage
initial
KTF
concentration
efficiency.
optimum
conditions
both
activated
wastes
pH=
2,
dose
0.1
g/L
C0,KTF=
5
mg/L
efficiency
98.14%
ROP-ZnCl2,
0.3
C0,KTF
=
20
a
99.84%
RAL-ZnCl2
bio-sorbent.
International Journal of Chemical Engineering,
Journal Year:
2024,
Volume and Issue:
2024, P. 1 - 14
Published: May 14, 2024
This
research
paper
focuses
on
the
removal
of
nonsteroidal
anti-inflammatory
drug,
ibuprofen,
from
an
aqueous
solution
using
a
dissolved
air
flotation
process.
The
comparison
different
types
cationic
surface-active
agents
such
as
cetyltrimethyl
ammonium
bromide
(CTAB),
tetrabutyl
(TBAB),
and
octyltrimethyl
(OTAB)
have
been
employed
to
scrutinize
effective
ecotoxic
pharmaceutically
active
compound.
work
included
influencing
parameters
pressure,
contact
time,
surfactant
dosage,
pH,
flow
rate,
initial
concentration
owing
best-optimized
conditions.
maximum
rate
96.09%
was
achieved
at
15
min
for
CTAB,
TBAB
had
62.36%
45
min,
89.6%
obtained
OTAB
30
with
50
mg
L−1
pH
=
4.
better
optimized
dosage
CTAB
0.6
g,
1.2
1.0
g.
It
observed
that
geometric
shape
greater
impacts
contaminants’
efficiency.
were
combined
find
out
best
possible
contaminants.
synergistic
effect
augments
surfactant-based
occurrence
be
in
forming
good
foaming
tends
lower
critical
micelle
(CMC).
From
evaluation
kinetic
models,
pseudo-second-order
kinetics
fitted
experimental
data
best.
Furthermore,
formed
metabolites
identified
gas
chromatography-mass
spectrometry
found
less
toxic
than
parenting
compounds.
