Mealtime clocking versus calorie counting for weight loss DOI Open Access
Leinys S. Santos‐Báez, Blandine Laferrère

Obesity, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

Obesity affects one-half of US adults and is a costly public health issue [(1)]. Lifestyle intervention with focus on caloric restriction (CR) remains the first main recommendation for weight loss, but it tedious, imposes burden patients who do not always have resources to implement it, rarely sustainable in long term. Meal timing has recently been shown be key factor consider dietary interventions, addition calorie amount diet composition. Late eating, having prolonged eating windows, erratic patterns are associated obesity metabolic disorder [(2-4)]. Time restricted (TRE), i.e., limiting number hours during which one can eat day, may present useful less-cumbersome alternative CR achieve loss humans [(2, 5)]. In study by Oldenburg et al. [(6)], 88 participants mean age 43.2 years baseline window duration ~14 h were randomized 12-week intervention: either an 8-h TRE, 15% CR, or unrestricted (UE). A battery tests was performed at end assess total body fat dual x-ray absorptiometry, subcutaneous visceral adipose tissue abdominal magnetic resonance, insulin sensitivity flexibility two-step clamp indirect calorimetry, sleep physical activity actigraphy, glucose continuous monitoring. Calorie intake assessed recalls. Additionally, meal recorded real time 2-week intervention. The TRE UE groups required time-stamp their meals myCircadianClock phone application, whereas group could use MyFitnessPal monitor calories. established using data from application recalls, energy nutrient 24 authors including senior author Lisa Chow, should complimented this trial, used comprehensive composition measurements had excellent retention rate 92%. shortened ~4 10-h window, 2 short target, resulting 3 kg (95% confidence interval [CI]: −4.9 1.3). did change lost 4.1 1.6 kg, respectively, no difference between groups. There expenditure group, improve composition, glycemia (measured via clamp, hemoglobin A1c), when compared Although aimed reduction daily calories, effective only 9%, explain absence weight-loss differences TRE. Nevertheless, quality interpreted caution, as measured recalls only, notoriously inaccurate [(7)]. resulted greater more hunger than groups, decrease 1 h, 10%, effect tissue. results well-conducted trial state-of-the art measures metabolism show that applying self-selected modest reasonable [(6)]. However, significant cohort individuals without syndrome, bringing into question efficacy 3-month although possibly increasing adherence, necessarily aligned each participant chronotype, muddied results. there good sex distribution, young predominantly White, generalizability wider different ethnicity needs determined. More research needed elucidate impact optimal window; whether clinical obesity, rather simple [(8)], target population; longer intervention, perhaps coupled earlier distribution other lifestyle modification, metabolism. Blandine Laferrère disclosed financial relationship UpToDate membership Society Governing Board. Leinys S. Santos-Báez receives support Russell Berrie Foundation Fellow Award Leadership Education Advancement Program (LEAP) Early Career Scholars American Psychological Association.

Language: Английский

Chrononutrition in Chronic Kidney Disease DOI Open Access
Pilar C. Castro-Mata, Alfonso M. Cueto‐Manzano, Bárbara Vizmanos

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 389 - 389

Published: Jan. 22, 2025

Chrononutrition, the study of interaction between biological rhythms and nutrition, has emerged as a promising field for addressing metabolic health. However, its role in chronic kidney disease (CKD) remains underexplored. CKD patients often experience circadian disruptions due to renal, metabolic, treatment-related, lifestyle factors, which may influence their nutritional status clinical outcomes. Objective: synthesize analyze existing evidence on chrononutrition patients, identify knowledge gaps, propose directions future research across different stages CKD. Initially, this review contextualizes physiology, alignment, chronodisruption explore such factors focusing variables already studied general population. We discuss how dietary timing habit adjustments could outcomes, offering insights into impacts management. This new approach optimize patient care, encouraging further research, particularly development personalized strategies disease.

Language: Английский

Citations

0
Mealtime clocking versus calorie counting for weight loss DOI Open Access
Leinys S. Santos‐Báez, Blandine Laferrère

Obesity, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

Obesity affects one-half of US adults and is a costly public health issue [(1)]. Lifestyle intervention with focus on caloric restriction (CR) remains the first main recommendation for weight loss, but it tedious, imposes burden patients who do not always have resources to implement it, rarely sustainable in long term. Meal timing has recently been shown be key factor consider dietary interventions, addition calorie amount diet composition. Late eating, having prolonged eating windows, erratic patterns are associated obesity metabolic disorder [(2-4)]. Time restricted (TRE), i.e., limiting number hours during which one can eat day, may present useful less-cumbersome alternative CR achieve loss humans [(2, 5)]. In study by Oldenburg et al. [(6)], 88 participants mean age 43.2 years baseline window duration ~14 h were randomized 12-week intervention: either an 8-h TRE, 15% CR, or unrestricted (UE). A battery tests was performed at end assess total body fat dual x-ray absorptiometry, subcutaneous visceral adipose tissue abdominal magnetic resonance, insulin sensitivity flexibility two-step clamp indirect calorimetry, sleep physical activity actigraphy, glucose continuous monitoring. Calorie intake assessed recalls. Additionally, meal recorded real time 2-week intervention. The TRE UE groups required time-stamp their meals myCircadianClock phone application, whereas group could use MyFitnessPal monitor calories. established using data from application recalls, energy nutrient 24 authors including senior author Lisa Chow, should complimented this trial, used comprehensive composition measurements had excellent retention rate 92%. shortened ~4 10-h window, 2 short target, resulting 3 kg (95% confidence interval [CI]: −4.9 1.3). did change lost 4.1 1.6 kg, respectively, no difference between groups. There expenditure group, improve composition, glycemia (measured via clamp, hemoglobin A1c), when compared Although aimed reduction daily calories, effective only 9%, explain absence weight-loss differences TRE. Nevertheless, quality interpreted caution, as measured recalls only, notoriously inaccurate [(7)]. resulted greater more hunger than groups, decrease 1 h, 10%, effect tissue. results well-conducted trial state-of-the art measures metabolism show that applying self-selected modest reasonable [(6)]. However, significant cohort individuals without syndrome, bringing into question efficacy 3-month although possibly increasing adherence, necessarily aligned each participant chronotype, muddied results. there good sex distribution, young predominantly White, generalizability wider different ethnicity needs determined. More research needed elucidate impact optimal window; whether clinical obesity, rather simple [(8)], target population; longer intervention, perhaps coupled earlier distribution other lifestyle modification, metabolism. Blandine Laferrère disclosed financial relationship UpToDate membership Society Governing Board. Leinys S. Santos-Báez receives support Russell Berrie Foundation Fellow Award Leadership Education Advancement Program (LEAP) Early Career Scholars American Psychological Association.

Language: Английский

Citations

0