Adaptive multi-view learning method for enhanced drug repurposing using chemical-induced transcriptional profiles, knowledge graphs, and large language models DOI Creative Commons
Yudong Yan,

Yinqi Yang,

Zhuohao Tong

et al.

Journal of Pharmaceutical Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 101275 - 101275

Published: March 1, 2025

Language: Английский

Global Regulatory Frameworks for the Use of Artificial Intelligence (AI) in the Healthcare Services Sector DOI Open Access
Kavitha Palaniappan,

Elaine Yan Ting Lin,

Silke Vogel

et al.

Healthcare, Journal Year: 2024, Volume and Issue: 12(5), P. 562 - 562

Published: Feb. 28, 2024

The healthcare sector is faced with challenges due to a shrinking workforce and rise in chronic diseases that are worsening demographic epidemiological shifts. Digital health interventions include artificial intelligence (AI) being identified as some of the potential solutions these challenges. ultimate aim AI systems improve patient’s outcomes satisfaction, overall population’s health, well-being professionals. applications services vast expected assist, automate, augment several services. Like any other emerging innovation, also comes its own risks requires regulatory controls. A review literature was undertaken study existing landscape for developed nations. In global landscape, most regulations revolve around Software Medical Device (SaMD) regulated under digital products. However, it necessary note current may not suffice AI-based technologies capable working autonomously, adapting their algorithms, improving performance over time based on new real-world data they have encountered. Hence, convergence healthcare, similar voluntary code conduct by US-EU Trade Technology Council, would be beneficial all nations, developing or developed.

Language: Английский

Citations

44

Antimicrobial resistance crisis: could artificial intelligence be the solution? DOI Creative Commons
Guangyu Liu, Dan Yu,

Mei-Mei Fan

et al.

Military Medical Research, Journal Year: 2024, Volume and Issue: 11(1)

Published: Jan. 23, 2024

Abstract Antimicrobial resistance is a global public health threat, and the World Health Organization (WHO) has announced priority list of most threatening pathogens against which novel antibiotics need to be developed. The discovery introduction are time-consuming expensive. According WHO’s report antibacterial agents in clinical development, only 18 have been approved since 2014. Therefore, critically needed. Artificial intelligence (AI) rapidly applied drug development its recent technical breakthrough dramatically improved efficiency antibiotics. Here, we first summarized recently marketed antibiotics, antibiotic candidates development. In addition, systematically reviewed involvement AI utilization, including small molecules, antimicrobial peptides, phage therapy, essential oils, as well mechanism prediction, stewardship.

Language: Английский

Citations

39

Supervised machine learning in drug discovery and development: Algorithms, applications, challenges, and prospects DOI Creative Commons
George Obaido, Ibomoiye Domor Mienye, Oluwaseun Francis Egbelowo

et al.

Machine Learning with Applications, Journal Year: 2024, Volume and Issue: 17, P. 100576 - 100576

Published: July 24, 2024

Language: Английский

Citations

20

Revolutionizing Prostate Cancer Therapy: Artificial intelligence – based Nanocarriers for Precision Diagnosis and Treatment DOI
Moein Shirzad,

Afsaneh Salahvarzi,

Sobia Razzaq

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104653 - 104653

Published: Feb. 1, 2025

Language: Английский

Citations

3

Advances in Artificial Intelligence (AI)-assisted approaches in drug screening DOI Creative Commons
Samvedna Singh, Himanshi Gupta, Priyanshu Sharma

et al.

Artificial Intelligence Chemistry, Journal Year: 2023, Volume and Issue: 2(1), P. 100039 - 100039

Published: Dec. 19, 2023

Artificial intelligence (AI) is revolutionizing the current process of drug design and development, addressing challenges encountered in its various stages. By utilizing AI, efficiency significantly improved through enhanced precision, reduced time cost, high-performance algorithms AI-enabled computer-aided (CADD). Effective screening techniques are crucial for identifying potential hit compounds from large volumes data compound repositories. The inclusion AI discovery, including lead molecules, has proven to be more effective than traditional vitro assays. This articlereviews advancements methods achieved AI-enhanced applications, machine learning (ML), deep (DL) algorithms. It specifically focuses on applications discovery phase, exploring strategies optimization such as Quantitative structure-activity relationship (QSAR) modeling, pharmacophore de novo designing, high-throughput virtual screening. Valuable insights into different aspects discussed, highlighting role AI-based tools, pipelines, case studies simplifying complexities associated with discovery.

Language: Английский

Citations

38

Strategies of Artificial intelligence tools in the domain of nanomedicine DOI

Mohammad Habeeb,

Huay Woon You, Mutheeswaran Umapathi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 91, P. 105157 - 105157

Published: Nov. 10, 2023

Language: Английский

Citations

27

Continuous flow synthesis enabling reaction discovery DOI Creative Commons
Antonella Ilenia Alfano, Jorge García‐Lacuna, Oliver Griffiths

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(13), P. 4618 - 4630

Published: Jan. 1, 2024

This article defines the role that continuous flow chemistry can have in new reaction discovery, thereby creating molecular assembly opportunities beyond our current capabilities. Most notably focus is based upon photochemical, electrochemical and temperature sensitive processes where methods machine assisted processing significant impact on chemical reactivity patterns. These platforms are ideally placed to exploit future innovation data acquisition, feed-back control through artificial intelligence (AI) learning (ML) techniques.

Language: Английский

Citations

15

Advanced Design of Soft Robots with Artificial Intelligence DOI Creative Commons
Ying Cao, Bingang Xu, Bin Li

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: June 13, 2024

In recent years, breakthrough has been made in the field of artificial intelligence (AI), which also revolutionized industry robotics. Soft robots featured with high-level safety, less weight, lower power consumption have always one research hotspots. Recently, multifunctional sensors for perception soft robotics rapidly developed, while more algorithms and models machine learning high accuracy optimized proposed. Designs AI advanced ranging from multimodal sensing, human–machine interaction to effective actuation robotic systems. Nonetheless, comprehensive reviews concerning new developments strategies ingenious design systems equipped are rare. Here, development is systematically reviewed AI. First, background mechanisms briefed, after focused on how endow AI, including aspects feeling, thought reaction, illustrated. Next, applications summarized discussed together proposed performance enhancement. Design thoughts future intelligent pointed out. Finally, some perspectives put forward.

Language: Английский

Citations

12

Deep learning assisted prediction of osteogenic capability of orthopedic implant surfaces based on early cell morphology DOI
Andi Li, Xinyi Li, Zhiwen Zhang

et al.

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

1

Two heads are better than one: Unravelling the potential Impact of Artificial Intelligence in nanotechnology DOI Creative Commons
Gaurav Gopal Naik,

Vijay A. Jagtap

Nano TransMed, Journal Year: 2024, Volume and Issue: 3, P. 100041 - 100041

Published: July 9, 2024

Artificial Intelligence (AI) and Nanotechnology are two cutting-edge fields that hold immense promise for revolutionizing various aspects of science, technology, everyday life. This review delves into the intersection these disciplines, highlighting synergistic relationship between AI Nanotechnology. It explores how techniques such as machine learning, deep neural networks being employed to enhance efficiency, precision, scalability nanotechnology applications. Furthermore, it discusses challenges, opportunities, future prospects integrating with nanotechnology, paving way transformative advancements in diverse domains ranging from healthcare materials science environmental sustainability beyond.

Language: Английский

Citations

7