Mechanism of action of “cistanche deserticola–Polygala” in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis DOI Creative Commons
Shaoqiang Wang, Yifan Wang

IET Systems Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 11, 2024

Abstract This article used network pharmacology, molecular docking, GEO analysis, and Gene Set Enrichment Analysis to obtain 38 main chemical components 66 corresponding targets involved in Alzheimer's disease (AD) treatment "Cistanche deserticola‐Polygala". Through further Ontology Kyoto Encyclopaedia of Genes Genomes enrichment we obtained AD signalling pathways, calcium other pathways related the with “Cistanche deserticola‐Polygala”. Molecular docking showed that most core had good binding ability targets. aims reveal mechanism deserticola‐Polygala” treating provide a basis for

Language: Английский

Enhanced lithology identification with few-shot well-logging data using a Confidence-Enhanced Semi-Supervised Meta-Learning Approach DOI
Hengxiao Li, Youzhuang Sun, Sibo Qiao

et al.

Measurement, Journal Year: 2025, Volume and Issue: unknown, P. 116762 - 116762

Published: Jan. 1, 2025

Language: Английский

Citations

4

The Artificial Intelligence-Enhanced Echocardiographic Detection of Congenital Heart Defects in the Fetus: A Mini-Review DOI Creative Commons

Khadiza Tun Suha,

Hugh Lubenow,

Stefania Soria-Zurita

et al.

Medicina, Journal Year: 2025, Volume and Issue: 61(4), P. 561 - 561

Published: March 21, 2025

Artificial intelligence (AI) is rapidly gaining attention in radiology and cardiology for accurately diagnosing structural heart disease. In this review paper, we first outline the technical background of AI echocardiography then present an array clinical applications, including image quality control, cardiac function measurements, defect detection, classifications. Collectively, answer how integrating technologies can help improve detection congenital defects. Particularly, superior sensitivity AI-based (CHD) fetus (>90%) allows it to be potentially translated into workflow as effective screening tool obstetric setting. However, current still have many limitations, more technological developments are required enable these reach their full potential. Also, diagnostic should resolve ethical concerns. Otherwise, deploying may not address low-resource populations’ healthcare access disadvantages. Instead, will further exacerbate disparities. We envision that, through combination tele-echocardiography AI, medical facilities gain CHD at prenatal stage.

Language: Английский

Citations

0

Mechanism of action of “cistanche deserticola–Polygala” in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis DOI Creative Commons
Shaoqiang Wang, Yifan Wang

IET Systems Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 11, 2024

Abstract This article used network pharmacology, molecular docking, GEO analysis, and Gene Set Enrichment Analysis to obtain 38 main chemical components 66 corresponding targets involved in Alzheimer's disease (AD) treatment "Cistanche deserticola‐Polygala". Through further Ontology Kyoto Encyclopaedia of Genes Genomes enrichment we obtained AD signalling pathways, calcium other pathways related the with “Cistanche deserticola‐Polygala”. Molecular docking showed that most core had good binding ability targets. aims reveal mechanism deserticola‐Polygala” treating provide a basis for

Language: Английский

Citations

0