Fructilactobacillus frigidiflavus sp. nov., a pigmented species, and Levilactobacillus lettrarii sp. nov., a propionate-producing species isolated from sourdough

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Journal Year: 2025, Volume and Issue: 75(3)

Published: March 20, 2025

The sourdough isolates FUA3702, FUA3912 and FUA3913 T , as well FUA3695 FUA3914, could not be identified to known species of the Lactobacillaceae . 16S rRNA gene sequences FUA3702 FUA3913, FUA3914 were>99% identical Fructilactobacillus sanfranciscensis Levilactobacillus lanxiensis respectively. average nucleotide identity (ANI) digital DNA–DNA hybridization (dDDH) values strain when compared Fl. were 83.67 26.60%, In addition, strains produce different levels a yellow C30 carotenoid, but pigmentation has been described in ANI dDDH Lv. langxiensis 95.22 61.20%, convert lactate 1,2-propanediol further propionate. conversion propionate by single documented for any Based on genomic physiological characteristics, we proposed novel frigidiflavus sp. nov. (=DSM 118650 =LMG 33758 ) lettrarii 118651 33759 ).

Language: Английский

---

Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Aug. 7, 2024

Abstract Background Vitamin A is essential for physiological processes like vision and immunity. A’s effect on gut microbiome composition, which affects absorption metabolism of other vitamins, still unknown. Here we examined the relationship between metagenome composition six vitamin A-related metabolites (two retinoid: -retinol, 4 oxoretinoic acid (oxoRA) four carotenoid metabolites, including beta-cryptoxanthin three carotene diols). Methods We included 1053 individuals from TwinsUK cohort with measured in serum faeces, diet history, assessed by shotgun sequencing. Results were replicated 327 women ZOE PREDICT-1 study. Five positively correlated alpha diversity ( r = 0.15 to 0.20, p < × 10 −6 ). Carotenoid compounds short-chain fatty-acid-producing bacteria Faecalibacterium prausnitzii Coprococcus eutactus. Retinol was not associated any microbial species. found that could predict circulating levels carotenoids AUCs ranging 0.66 0.74 using random forest models, but retinol (AUC 0.52). The healthy eating index (HEI) strongly all compounds, retinoids. investigated mediating role a diversity, finding significantly mediated 18 25% HEI diversity. Conclusions Our results show strong links potential pattern.

Language: Английский

---

Multiomics analysis revealed anti-freezing mechanism ofStaphylococcus aureusin its anti-freezing strain

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

Frozen food is currently a common type. However, the presence of Staphylococcus aureus contamination caused serious challenge to frozen safety. In this study, we explored differences between sensitive strains and anti-freeze through multiomics analysis such as proteomics, phosphorylated metabolomics studies understand anti-freezing mechanism S. . This study compared proteomics metabolomic before after freezing. pre- post-freezing, antifreeze mainly responded low temperatures by enhancing antioxidant capacity, energy metabolism antibiotic synthesis freezing, while bacteria depended more on biofilm formation, nitrogen amino acid improve frost resistance adaptability. The ket gene sucD coaD in metabolic pathways, gapA1 tpiA glucose balance, asd gnd pathways protein synthesis, crtN context protective mechanisms stress response should be furthermore. research, arginine pathway, formation Adenosine triphosphate-binding cassette transporters other deserve special attention research. IMPORTANCE highlights importance understanding *Staphylococcus aureus* By analyzing metabolomics, it identifies key like metabolism, that enhance bacterial resistance, offering insights for improving preservation

Language: Английский

---

Evolution and ecology of C30 carotenoid synthesis in Lactobacillaceae and application of pigmented lactobacilli in pasta production

Food Microbiology, Journal Year: 2024, Volume and Issue: 127, P. 104688 - 104688

Published: Nov. 27, 2024

Language: Английский

---

Regulation of innate lymphoid cell by microbial metabolites

Journal of Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Language: Английский

---