The global, regional, and national disease burden of breast cancer attributable to tobacco from 1990 to 2019: a global burden of disease study

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 6, 2024

Abstract Objective Tobacco has been identified as a significant contributory element to the development of breast cancer. Our objective was evaluate spatiotemporal trends tobacco-related cancer at global, regional, and national scales during 1990–2019. Methods We extracted data on mortality, disability adjusted life years (DALYs), age-standardized mortality rate (ASMR), DALYs (ASDR) from Global Burden Disease (GBD) study 2019. Estimated annual percentage change (EAPC) computed assess temporal in ASDR ASMR. Results In 2019, deaths attributed were estimated be 35,439 (95% UI: 22,179–48,119) 1,060,590 622,550–1,462,580), respectively. These figures accounted for 5.1% 5.2% total burden ASMR increased low SDI regions, remained stable low-middle middle regions declined high high-middle regions. The attributable tobacco varied notably among nations. Oceania, Southern Latin America, Central Europe GBD with highest number DALYs. There positive relationship between value 2019 across 204 nations or territories. A negative association observed EAPC human index (HDI) (R = -0.55, p < 0.01 ASMR; R -0.56, ASDR). Conclusion is one important modifiable risk factor heterogeneity both spatial distribution can factors such aging, population growth, SDI. findings substantiate necessity expediting enforcement tobacco-free legislation order safeguard populations detrimental effects tobacco.

Language: Английский

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Fires as a source of annual ambient PM2.5 exposure and chronic health impacts in Europe

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 922, P. 171314 - 171314

Published: Feb. 28, 2024

Chronic exposure to ambient PM2.5 is the largest environmental health risk in Europe. We used a chemical transport model and recent response functions simulate PM2.5, contribution from fires related impacts over Europe 1990 2019. Our estimation indicates that excess death burden declined across at rate of 10,000 deaths per year, 0.57 million (95 % confidence intervals: 0.44–0.75 million) 0.28 (0.19–0.42 specified period. Among these deaths, approximately 99 were among adults, while only around 1 occurred children. findings reveal steady increase fire mortality fractions (excess 1000 PM2.5) 2 13 Notably, countries Eastern exhibited significantly higher experienced more pronounced increases compared those Western Central performed sensitivity analyses by considering be toxic as other sources, indicated studies. By than sources results an increased relative reaching 2.5–13 indicate requirement larger mitigation adaptation efforts sustainable forest management policies avert rising fires.

Language: Английский

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Modelling Health Implications of Extreme PM2.5 Concentrations in Indian Sub-Continent: Comprehensive Review with Longitudinal Trends and Deep Learning Predictions

Technology in Society, Journal Year: 2025, Volume and Issue: unknown, P. 102843 - 102843

Published: Feb. 1, 2025

Language: Английский

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Multinational modelling of PM2.5 and CO exposures from household air pollution in peri-urban Cameroon, Ghana and Kenya

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 26, 2025

Abstract In sub-Saharan Africa, approximately 85% of the population uses polluting cooking fuels (e.g. wood, charcoal). Incomplete combustion these generates household air pollution (HAP), containing fine particulate matter (PM 2.5 ) and carbon monoxide (CO). Due to large spatial variability, increased quantification HAP levels is needed improve exposure assessment in Africa. The CLEAN-Air(Africa) study included 24-h monitoring PM CO kitchen concentrations (n pm2.5 = 248/n 207) female primary cook exposures 245/n 222) peri-urban households Obuasi (Ghana), Mbalmayo (Cameroon) Eldoret (Kenya). measurements were combined with survey data on patterns, socioeconomic characteristics ambient proxies walking time nearest road) separate mixed-effect log-linear regression models. Model coefficients applied a larger 937) only quantitatively scale up exposures. final models moderately explained variation mean (R 2 0.40) 0.26) concentration measurements, 0.27) 0.14) Primary/secondary fuel type was significant predictor all four Other predictors location size; financial security rental status predictive concentrations. Cooking location, Including objective (from temperature sensors) from 143) substantially improved (by 52%) variability model, but not model. Socioeconomic markers strongly associated while environment variables more levels.

Language: Английский

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Fine particulate matter manipulates immune response to exacerbate microbial pathogenesis in the respiratory tract

European Respiratory Review, Journal Year: 2024, Volume and Issue: 33(173), P. 230259 - 230259

Published: July 1, 2024

Particulate matter with a diameter ≤2.5 μm (PM 2.5 ) poses substantial global challenge, growing recognition of pathogens contributing to diseases associated exposure PM . Recent studies have focused on , which impairs the immune cells in response microbial infections and potentially contributes development severe respiratory tract. Accordingly, changes function microecology mediated by are important factors that enhance risk pathogenesis. These garnered significant interest. In this review, we summarise recent potential mechanisms involved -mediated system disruption exacerbation pathogenesis We also discuss crucial areas for future research address gaps our understanding develop effective strategies combat adverse health effects

Language: Английский

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Biomass fuels related-PM2.5 promotes lung fibroblast-myofibroblast transition through PI3K/AKT/TRPC1 pathway

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 276, P. 116309 - 116309

Published: April 10, 2024

Emerging evidence has suggested that exposure to PM

Language: Английский

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Air pollution we breathe: Assessing the air quality and human health impact in a megacity of Southeast Asia

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 942, P. 173403 - 173403

Published: June 5, 2024

Language: Английский

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Effect of double-layer filter cartridge with an inner cone on the pulse-jet cleaning performance of cartridge dust collectors

Separation and Purification Technology, Journal Year: 2023, Volume and Issue: 328, P. 125058 - 125058

Published: Sept. 12, 2023

Language: Английский

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PM2.5 induces a senescent state in mouse AT2 cells

Environmental Pollution, Journal Year: 2024, Volume and Issue: 347, P. 123686 - 123686

Published: Feb. 29, 2024

Language: Английский

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Elemental composition and health risk assessment of PM10, PM2.5, at different microenvironments: Addis Ababa, Ethiopia

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(10), P. e0309995 - e0309995

Published: Oct. 25, 2024

This study was designed to evaluate the health risks faced by inhabitants living in slum areas of Addis Ababa, Ethiopia. The levels PM2.5 and PM10 elemental composition were measured indoors (in kitchen room) outdoors (at roadside). A total 75 sampling locations (45 indoor 30 outdoor) selected for study. determined using an AROCET531S instrument, while universal air pump used determination trace elements inductively coupled plasma-optical emission spectroscopy (ICP‒OES). impacts PMs on twelve microenvironments (MEs), where they spend much their daily time, estimated. amounts PM10, metals found nine or MEs ranged from 10.6-119, 128-185, 0.007-0.197 μg m-3, respectively. According United States Environment Protection Agency (USEPA) guidelines, ten can cause significant problems (HI > 1) due PM10. Thus, special attention should be given stakeholders/inhabitants minimize long-term exposure. assessed risk who most lives. revealed that lifetime cancer values individual cumulative within tolerable range set USEPA guidelines.

Language: Английский

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